iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000013505.10	ENSDART00000139003.1	ENSDARP00000120324.1
ENSDARG00000013505.10	ENSDART00000025770.8	ENSDARP00000018676.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.90e-44	151.1	30	154
UBD/Alpha-Helix/UBA	7.80e-10	39.5	169	207

Active Site

Position(s)	Description	Evidence
100	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 12   dppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsve 99
           +++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a++++
   Q: 30   TSKNQIKVDLVDE-NFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTLR 115
           456899*******.9***************************************************99********9..********** PP
   S: 100  svllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 116  TVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 154
           ************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+++l++MGFd+++++ aL + ++++e A+e+Ll+
   Q: 169  EYTRKIDKLCAMGFDKNAVIVALSSKSWDVETATELLLS 207
           57889********************************97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEESQENTGI HPFHYFRLRR ERWSGQPKCT SKNQIKVDLV DENFTELKGE IAGPPDTPYE 60
GGRYQLEIKI PETYPFNPPK VRFITKIWHP NISSVTGAIC LDILKDQWAA AMTLRTVLLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCAGATGA TGACAACATT CACAGAGTCA TGACTACATG GAGGAGAGTC AAGAAAATAC 60
TGGAATACAC CCATTTCATT ATTTCCGTCT GCGCAGAGAA AGGTGGTCTG GTCAACCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024276	Choloepus hoffmanni	93.20	7.00e-71	259.00
IUUC-Eeu-035103	Erinaceus europaeus	69.53	1.00e-46	178.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence