iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071595

Ensembl Protein ID

ENSONIP00000006171.1

UniProt Accession

I3JBD1; I3JBD1_ORENI

Genbank Protein ID

ENSONIP00000006171

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01012242

Gene Name

UBE2K (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000004908.1	ENSONIT00000006175.1	ENSONIP00000006171.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.20e-46	156.9	8	146
UBD/Alpha-Helix/UBA	1.30e-09	38.3	161	199
UBD/UBC-like/UBD_UBC	1.50e-72	242.6	8	149

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 146
           *9..**********************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+++l++MGF++++++ aL + ++++e A+e+Ll+
   Q: 161  EYTRKIDKLCAMGFEKNAVIVALSSKSWDVETATELLLS 199
           57889********************************97 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++el+++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELKGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++ar+w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWS 149
           ****************************************************5 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELK GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTTTTCT ACACCTTTTC TACGCATATG TTTGTGTCAT CAAAATGCAT ATAAGGCCTT 60
TGGTCTGATC ATCAGATGAA AACGCCTCCT TGCTTGTCTA ATGTGTTAGA GGCAGTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	51.55	4.00e-28	118.00
IUUC-Aml-001286	Ailuropoda melanoleuca	96.50	7.00e-107	379.00
IUUC-Apl-004122	Anas platyrhynchos	89.00	1.00e-94	338.00
IUUC-Ath-006637	Arabidopsis thaliana	46.86	2.00e-41	162.00
IUUC-Ago-007714	Ashbya gossypii	45.70	1.00e-38	152.00
IUUC-Ame-011454	Astyanax mexicanus	99.50	2.00e-109	387.00
IUUC-Bta-012992	Bos taurus	96.50	7.00e-107	379.00
IUUC-Cel-018353	Caenorhabditis elegans	53.77	2.00e-58	218.00
IUUC-Cja-019051	Callithrix jacchus	96.00	5.00e-106	376.00
IUUC-Cfa-020016	Canis familiaris	96.50	7.00e-107	379.00
IUUC-Cpo-022026	Cavia porcellus	96.50	7.00e-107	379.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.47	2.00e-41	162.00
IUUC-Csa-023059	Chlorocebus sabaeus	96.50	7.00e-107	379.00
IUUC-Cho-024276	Choloepus hoffmanni	92.52	5.00e-71	259.00
IUUC-Cin-025598	Ciona intestinalis	60.71	6.00e-56	210.00
IUUC-Csv-025831	Ciona savignyi	62.24	3.00e-54	204.00
IUUC-Cne-027068	Cryptococcus neoformans	40.89	1.00e-40	159.00
IUUC-Dre-028139	Danio rerio	98.50	1.00e-108	385.00
IUUC-Eca-033428	Equus caballus	96.50	7.00e-107	379.00
IUUC-Eeu-035103	Erinaceus europaeus	68.75	2.00e-46	177.00
IUUC-Fca-035366	Felis catus	96.50	7.00e-107	379.00
IUUC-Fal-037016	Ficedula albicollis	96.50	7.00e-107	379.00
IUUC-Gmo-039135	Gadus morhua	99.50	7.00e-109	385.00
IUUC-Ggr-039768	Gaeumannomyces graminis	40.10	3.00e-26	111.00
IUUC-Gac-041503	Gasterosteus aculeatus	100.00	8.00e-110	389.00
IUUC-Ggo-045032	Gorilla gorilla	96.50	7.00e-107	379.00
IUUC-Hsa-046490	Homo sapiens	96.50	7.00e-107	379.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	96.50	7.00e-107	379.00
IUUC-Kpa-049297	Komagataella pastoris	49.67	3.00e-34	138.00
IUUC-Laf-053688	Loxodonta africana	88.73	4.00e-97	347.00
IUUC-Mcc-055606	Macaca mulatta	96.50	7.00e-107	379.00
IUUC-Mor-056946	Magnaporthe oryzae	37.93	9.00e-24	103.00
IUUC-Mpo-057441	Magnaporthe poae	41.59	3.00e-26	112.00
IUUC-Mvi-060346	Microbotryum violaceum	42.00	6.00e-34	137.00
IUUC-Mmr-061211	Microcebus murinus	96.50	7.00e-107	379.00
IUUC-Mdo-062458	Monodelphis domestica	95.50	3.00e-104	370.00
IUUC-Mmu-063648	Mus musculus	96.50	7.00e-107	379.00
IUUC-Mlu-067682	Myotis lucifugus	89.39	4.00e-97	347.00
IUUC-Ncr-068749	Neurospora crassa	48.08	2.00e-38	152.00
IUUC-Nle-069712	Nomascus leucogenys	96.11	2.00e-95	341.00
IUUC-Opr-070651	Ochotona princeps	96.50	7.00e-107	379.00
IUUC-Oan-073058	Ornithorhynchus anatinus	95.95	3.00e-76	276.00
IUUC-Ocu-074939	Oryctolagus cuniculus	96.50	7.00e-107	379.00
IUUC-Obr-076838	Oryza brachyantha	48.99	8.00e-32	130.00
IUUC-Ola-087043	Oryzias latipes	100.00	8.00e-110	389.00
IUUC-Olu-087846	Ostreococcus lucimarinus	47.15	2.00e-42	165.00
IUUC-Oar-089673	Ovis aries	89.39	1.00e-97	348.00
IUUC-Ptr-091295	Pan troglodytes	96.50	7.00e-107	379.00
IUUC-Psi-093498	Pelodiscus sinensis	96.50	7.00e-107	379.00
IUUC-Ppa-095326	Physcomitrella patens	46.19	5.00e-40	157.00
IUUC-Pfo-096174	Poecilia formosa	99.00	3.00e-109	387.00
IUUC-Pab-098279	Pongo abelii	96.50	7.00e-107	379.00
IUUC-Pca-100782	Procavia capensis	96.00	7.00e-105	372.00
IUUC-Pva-102147	Pteropus vampyrus	67.61	2.00e-55	207.00
IUUC-Rno-104984	Rattus norvegicus	96.50	7.00e-107	379.00
IUUC-Sce-106394	Saccharomyces cerevisiae	43.68	3.00e-36	144.00
IUUC-Sit-110639	Setaria italica	48.48	5.00e-40	157.00
IUUC-Sbi-113986	Sorghum bicolor	48.48	8.00e-40	156.00
IUUC-Sre-115046	Sporisorium reilianum	39.22	2.00e-37	148.00
IUUC-Ssc-116314	Sus scrofa	96.50	7.00e-107	379.00
IUUC-Tru-118196	Takifugu rubripes	87.56	6.00e-105	373.00
IUUC-Tsy-119208	Tarsius syrichta	94.44	2.00e-103	368.00
IUUC-Tni-119667	Tetraodon nigroviridis	99.50	1.00e-109	388.00
IUUC-Tme-127024	Tuber melanosporum	50.32	1.00e-38	153.00
IUUC-Uma-129512	Ustilago maydis	40.20	2.00e-37	149.00
IUUC-Vda-129947	Verticillium dahliae	37.86	2.00e-31	129.00
IUUC-Vpa-130481	Vicugna pacos	96.45	6.00e-105	372.00
IUUC-Xma-134165	Xiphophorus maculatus	99.50	2.00e-109	387.00
IUUC-Yli-134523	Yarrowia lipolytica	44.00	3.00e-34	138.00
IUUC-Zma-135733	Zea mays	47.62	3.00e-38	151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence