• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Dre-027884
Ensembl Protein ID ENSDARP00000120675.1
UniProt Accession F2Z4T6; F2Z4T6_DANRE
Genbank Protein ID ENSDARP00000120675
Protein Name Ubiquitin-related modifier 1
Genbank Nucleotide ID BX323065
Gene Name urm1; URM1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000091198.3 ENSDART00000142895.2 ENSDARP00000120675.1
ENSDARG00000091198.3 ENSDART00000129952.2 ENSDARP00000108653.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 39.39 1.00e-15 75.50 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Danio rerio
Functional Description
(View)

Functional Description


     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
 Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MAAPLGLHLE FGGGAELLFD GVKNHHVTLP DQSNPWDMKQ LLAWIRGNML KERPELFMQG 60
DTVRPGILVL INDADWELMG ELDYQLQDKD NVVFISTLHG G 101
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-027884|ULD,UBQ_Other|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTCCTGAGG ATGTGAGATT ACTTCCGGGT TTTACAACAA CATGGCAGCG CCCTTAGGTC 60
TGCATCTGGA GTTTGGGTTT GTATTTATTG TTTCCTTTAT CATTAATCTA TTTTTTTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027884|ULD,UBQ_Other|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway
Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1
Pfam

PF09138--Urm1
Gene Ontology

GO:0005829--C:cytosol
GO:0032447--P:protein urmylation
GO:0034227--P:tRNA thio-modification
GO:0002098--P:tRNA wobble uridine modification
KEGG dre:558120
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 76.24 3.00e-44 169.00
IUUC-Atr-003089 Amborella trichopoda 60.82 7.00e-31 124.00
IUUC-Apl-003382 Anas platyrhynchos 80.22 2.00e-40 156.00
IUUC-Aca-004981 Anolis carolinensis 79.21 2.00e-45 173.00
IUUC-Aly-005517 Arabidopsis lyrata 63.04 1.00e-30 124.00
IUUC-Ath-006718 Arabidopsis thaliana 63.10 6.00e-27 111.00
IUUC-Ago-007917 Ashbya gossypii 41.24 1.00e-18 84.00
IUUC-Acl-008054 Aspergillus clavatus 66.04 8.00e-16 74.70
IUUC-Afl-008704 Aspergillus flavus 56.67 6.00e-21 91.70
IUUC-Aor-009890 Aspergillus oryzae 55.88 3.00e-24 103.00
IUUC-Bta-012448 Bos taurus 77.23 1.00e-44 170.00
IUUC-Bci-013865 Botrytis cinerea 44.55 3.00e-20 90.10
IUUC-Bdi-014980 Brachypodium distachyon 70.31 2.00e-24 103.00
IUUC-Bol-016055 Brassica oleracea 60.53 4.00e-25 105.00
IUUC-Bra-016845 Brassica rapa 60.53 4.00e-25 105.00
IUUC-Cel-018485 Caenorhabditis elegans 32.04 3.00e-10 56.60
IUUC-Cja-019587 Callithrix jacchus 78.22 1.00e-44 170.00
IUUC-Cfa-020653 Canis familiaris 76.24 2.00e-44 169.00
IUUC-Cpo-021622 Cavia porcellus 78.22 1.00e-44 170.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 57.29 8.00e-26 108.00
IUUC-Csa-023756 Chlorocebus sabaeus 74.68 3.00e-32 130.00
IUUC-Cgl-026518 Colletotrichum gloeosporioides 43.56 2.00e-19 87.00
IUUC-Cne-026953 Cryptococcus neoformans 53.47 5.00e-26 110.00
IUUC-Cme-027314 Cyanidioschyzon merolae 43.30 3.00e-18 82.80
IUUC-Dno-029262 Dasypus novemcinctus 75.00 1.00e-33 135.00
IUUC-Dor-030601 Dipodomys ordii 51.49 8.00e-22 94.70
IUUC-Dme-031893 Drosophila melanogaster 62.75 3.00e-31 125.00
IUUC-Ete-032773 Echinops telfairi 75.25 1.00e-41 160.00
IUUC-Eca-034187 Equus caballus 77.23 2.00e-44 169.00
IUUC-Eeu-034808 Erinaceus europaeus 73.27 3.00e-43 166.00
IUUC-Fca-036107 Felis catus 76.24 1.00e-44 170.00
IUUC-Fal-036607 Ficedula albicollis 79.12 7.00e-40 154.00
IUUC-Fox-037698 Fusarium oxysporum 47.12 8.00e-21 91.70
IUUC-Gmo-039492 Gadus morhua 85.15 6.00e-47 178.00
IUUC-Ggr-039965 Gaeumannomyces graminis 48.08 4.00e-20 90.50
IUUC-Gga-041268 Gallus gallus 79.21 3.00e-45 172.00
IUUC-Gac-042111 Gasterosteus aculeatus 83.17 2.00e-47 179.00
IUUC-Gma-043240 Glycine max 61.18 5.00e-25 105.00
IUUC-Ggo-045176 Gorilla gorilla 74.68 3.00e-26 110.00
IUUC-Hsa-046077 Homo sapiens 77.23 2.00e-38 150.00
IUUC-Itr-048111 Ictidomys tridecemlineatus 79.78 2.00e-33 133.00
IUUC-Kpa-049157 Komagataella pastoris 47.47 1.00e-19 87.40
IUUC-Lch-049889 Latimeria chalumnae 80.20 2.00e-46 176.00
IUUC-Lpe-050783 Leersia perrieri 68.25 4.00e-23 99.00
IUUC-Loc-052400 Lepisosteus oculatus 87.13 2.00e-49 186.00
IUUC-Lma-053259 Leptosphaeria maculans 45.45 8.00e-19 85.10
IUUC-Laf-053596 Loxodonta africana 75.73 1.00e-42 163.00
IUUC-Mcc-054845 Macaca mulatta 73.47 3.00e-39 152.00
IUUC-Meu-055968 Macropus eugenii 78.22 5.00e-45 172.00
IUUC-Mor-057126 Magnaporthe oryzae 44.23 6.00e-18 82.80
IUUC-Mpo-057311 Magnaporthe poae 47.52 5.00e-20 90.10
IUUC-Mtr-058266 Medicago truncatula 60.47 3.00e-25 106.00
IUUC-Mla-058847 Melampsora laricipopulina 38.61 2.00e-11 60.80
IUUC-Mga-059468 Meleagris gallopavo 80.22 2.00e-40 156.00
IUUC-Mvi-060235 Microbotryum violaceum 37.09 3.00e-19 87.40
IUUC-Mdo-061948 Monodelphis domestica 77.23 2.00e-44 169.00
IUUC-Mmu-063946 Mus musculus 76.24 1.00e-43 167.00
IUUC-Mac-064812 Musa acuminata 70.31 4.00e-25 105.00
IUUC-Mpu-066763 Mustela putorius furo 76.24 2.00e-43 166.00
IUUC-Mlu-066970 Myotis lucifugus 75.95 6.00e-33 131.00
IUUC-Ncr-068824 Neurospora crassa 42.57 1.00e-17 81.30
IUUC-Nle-069849 Nomascus leucogenys 74.68 3.00e-32 130.00
IUUC-Opr-070227 Ochotona princeps 78.22 1.00e-44 170.00
IUUC-Ont-072530 Oreochromis niloticus 84.16 4.00e-47 178.00
IUUC-Oan-073191 Ornithorhynchus anatinus 73.20 3.00e-39 152.00
IUUC-Ocu-074460 Oryctolagus cuniculus 76.53 6.00e-43 164.00
IUUC-Oba-075499 Oryza barthii 70.31 1.00e-23 102.00
IUUC-Obr-076896 Oryza brachyantha 65.62 2.00e-22 99.00
IUUC-Ogl-077834 Oryza glaberrima 70.31 4.00e-24 102.00
IUUC-Ogu-078622 Oryza glumaepatula 70.31 4.00e-24 102.00
IUUC-Oin-079358 Oryza indica 70.31 1.00e-23 102.00
IUUC-Olo-081035 Oryza longistaminata 57.58 4.00e-25 107.00
IUUC-Oni-082425 Oryza nivara 70.31 4.00e-24 102.00
IUUC-Opu-083461 Oryza punctata 69.84 3.00e-23 100.00
IUUC-Oru-084875 Oryza rufipogon 63.38 4.00e-22 95.50
IUUC-Oga-089128 Otolemur garnettii 77.23 2.00e-44 169.00
IUUC-Oar-089896 Ovis aries 77.23 1.00e-44 170.00
IUUC-Ptr-091618 Pan troglodytes 74.68 3.00e-26 110.00
IUUC-Pan-092238 Papio anubis 74.68 2.00e-32 130.00
IUUC-Psi-093879 Pelodiscus sinensis 79.21 1.00e-44 170.00
IUUC-Pma-094484 Petromyzon marinus 75.25 1.00e-33 134.00
IUUC-Ppa-095801 Physcomitrella patens 57.33 9.00e-23 97.80
IUUC-Pfo-097192 Poecilia formosa 86.14 2.00e-48 183.00
IUUC-Pab-098203 Pongo abelii 77.23 3.00e-38 149.00
IUUC-Pop-099614 Populus trichocarpa 58.33 4.00e-25 105.00
IUUC-Pca-100507 Procavia capensis 74.68 9.00e-33 130.00
IUUC-Ppe-101174 Prunus persica 61.62 4.00e-31 125.00
IUUC-Pva-102735 Pteropus vampyrus 77.23 3.00e-41 159.00
IUUC-Pgr-103510 Puccinia graminis 37.86 5.00e-11 59.70
IUUC-Ptt-103918 Puccinia triticina 37.62 4.00e-11 60.10
IUUC-Pte-104173 Pyrenophora teres 48.54 2.00e-21 94.00
IUUC-Pyt-104806 Pyrenophora triticirepentis 48.54 2.00e-21 94.00
IUUC-Rno-105820 Rattus norvegicus 77.23 2.00e-44 169.00
IUUC-Sce-106366 Saccharomyces cerevisiae 39.39 5.00e-16 75.50
IUUC-Sja-107727 Schizosaccharomyces japonicus 41.67 1.00e-16 78.20
IUUC-Spo-108074 Schizosaccharomyces pombe 39.00 2.00e-09 53.90
IUUC-Smo-108944 Selaginella moellendorffii 62.92 3.00e-27 112.00
IUUC-Sit-110277 Setaria italica 58.33 1.00e-24 103.00
IUUC-Sly-111505 Solanum lycopersicum 59.52 3.00e-26 109.00
IUUC-Stu-112076 Solanum tuberosum 59.52 3.00e-26 109.00
IUUC-Sbi-114274 Sorghum bicolor 60.53 4.00e-24 102.00
IUUC-Sre-114953 Sporisorium reilianum 57.00 1.00e-25 107.00
IUUC-Ssc-115418 Sus scrofa 77.23 3.00e-44 169.00
IUUC-Tgu-117311 Taeniopygia guttata 78.02 2.00e-39 153.00
IUUC-Tru-118598 Takifugu rubripes 84.27 1.00e-40 157.00
IUUC-Tni-120109 Tetraodon nigroviridis 82.35 6.00e-45 171.00
IUUC-Tca-120942 Theobroma cacao 57.50 4.00e-25 105.00
IUUC-Tre-122099 Trichoderma reesei 46.81 3.00e-14 69.30
IUUC-Tvi-122285 Trichoderma virens 50.96 1.00e-18 84.70
IUUC-Tae-125193 Triticum aestivum 63.38 2.00e-23 100.00
IUUC-Tur-126677 Triticum urartu 57.89 8.00e-21 92.00
IUUC-Tme-127120 Tuber melanosporum 46.15 9.00e-23 98.60
IUUC-Tbe-128050 Tupaia belangeri 59.41 5.00e-28 115.00
IUUC-Ttr-129019 Tursiops truncatus 74.26 4.00e-41 159.00
IUUC-Uma-129483 Ustilago maydis 56.00 3.00e-24 103.00
IUUC-Vda-129690 Verticillium dahliae 38.39 8.00e-15 72.00
IUUC-Vvi-131174 Vitis vinifera 59.04 3.00e-25 105.00
IUUC-Xma-133862 Xiphophorus maculatus 86.14 2.00e-48 183.00
IUUC-Yli-134398 Yarrowia lipolytica 45.26 5.00e-18 82.00
IUUC-Zma-134964 Zea mays 61.84 3.00e-23 99.80
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved