iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000057706.1	ENSRNOT00000082902.1	ENSRNOP00000070936.1
ENSRNOG00000057706.1	ENSRNOT00000078617.1	ENSRNOP00000075375.1
ENSRNOG00000057706.1	ENSRNOT00000086952.1	ENSRNOP00000069719.1
ENSRNOG00000057706.1	ENSRNOT00000079909.1	ENSRNOP00000071836.1
ENSRNOG00000057706.1	ENSRNOT00000082725.1	ENSRNOP00000074522.1

Annotation

DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.80e-12	46.6	107	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vC +C +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 107  VCRMCSRGDEDD-KLLLCDGCDDNYHIFCLLPP-LPEIPKGV-WRCPKCV 153
           8*********88.6*******************.*******8.******6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

PEPTEEDIEK NPELKKLQIY GAGPKMMGLG LMAKDKNLRK KDKEGPECPP TVGGKEELGG 60
EWKMESASPK TFLEGKEELS HSPEPCTKMT MRLRRNHSNA QFIESYVCRM CSRGDEDDKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTTCCTCC GCCAATTAGA TGAACTATTT TCTCTCAGCT TGAGAAATGT TTCTAACTAA 60
CCACTCTCAA ATAGGGGGCA TATACAATCC GATTTCTCTC GTTCATCACA GGATGAAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD
PF08429--PLU-1

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0009636--P:response to toxic substance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bra-017998	Brassica rapa	54.00	4.00e-13	72.00
IUUC-Eeu-034692	Erinaceus europaeus	87.07	0.00e+00	1810.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence