iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041195

UUCD1 version

UUC-GaG-00663

Ensembl Protein ID

ENSGALP00000052001.1

UniProt Accession

A0A1D5PGS8; A0A1D5PGS8_CHICK

Genbank Protein ID

ENSGALP00000052001

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000359

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000031282.1	ENSGALT00000057246.1	ENSGALP00000052001.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.70e-79	265.9	2459	2781

Active Site

Position(s)	Description	Evidence
2751	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 17   egldlgGvtreflallskelqnpd..lglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
           e+ + +G++r ++++ ++++ + d  ++lf +  +++ +t +p +++      +l++F+ +Gr+lg++l +++l++++l+++++k l
   Q: 2459 ENRKRHGSSRSVVDMELDDTDDGDdnAPLFyQPGKRGFYTPRPGKNTE----ARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVL 2541
           556777999999999999999988777888234444777777777765....89********************************* PP
   S: 101  lgkklsledleevdpelyks.lkeikena..esdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           lg+k++++d++ +dp +y+s  + i++++  ++d   +++dl+f ++ ++ +   ++eL+++G nipVt +N +eYv++++e+r+  
   Q: 2542 LGRKVNWHDFAFFDPVMYESlRQLILASQstDADAVFAAMDLAFAIDLCKEEGGGQVELISNGVNIPVTPQNVYEYVRKYAEHRMLV 2628
           ********************5555666655566889999************************************************ PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai....qwFwevleefsseerkafLqF 267
             ++ ++a+r+G+ +v+p+++l+ +t+e+++ll++G+ e++v++l ++t+++++  e+ +++    +wFw+++e++s++er++++ F
   Q: 2629 VAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLlqfkRWFWSIVEKMSMTERQDLVYF 2715
           ***************************************************9999999999989999******************** PP
   S: 268  vTgssrlPl..gGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +T+s++lP+  +Gf++++  +++ir   +d++lP++nTC+++L +P Yssk+ilk+kLl+Ai++ k+F++
   Q: 2716 WTSSPSLPAseEGFQPMP--SITIRP-PDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKT-KNFGF 2781
           *********999******..799999.99**********************************9.99875 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MTSIHFVVHP LPGTEDQLND RLREVSEKLN KYNLNSHPPL NVLEQATIKQ CVVGPNHAAF 60
LLEDGRVCRI GFSVQPDRLE LGKPDNSDGS KLSSGSGAGR TSRPGRTSDS PWFLSGSETL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCTCGA TCCACTTCGT GGTGCACCCG CTGCCGGGCA CCGAGGATCA GCTCAATGAC 60
CGGTGAGGGG CAGGCCCCGC GCGGCGGGGG GCGGAGGGGA GGGGCCGCCG GCGCGGCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR024725--E3_UbLigase_EDD_UBA
IPR000569--HECT_dom
IPR002004--PABP_HYD
IPR009091--RCC1/BLIP-II
IPR003126--Znf_UBR

PROSITE

PS50237--HECT
PS51309--PABC
PS51157--ZF_UBR

Pfam

PF11547--E3_UbLigase_EDD
PF00632--HECT
PF00658--PABP

SMART

SM00119--HECTc
SM00517--PolyA
SM00396--ZnF_UBR1

Gene Ontology

GO:0003723--F:RNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002217	Ailuropoda melanoleuca	96.11	0.00e+00	4437.00
IUUC-Apl-004165	Anas platyrhynchos	96.37	0.00e+00	4446.00
IUUC-Aca-004577	Anolis carolinensis	95.24	0.00e+00	3848.00
IUUC-Ame-010702	Astyanax mexicanus	83.10	0.00e+00	2416.00
IUUC-Bta-012313	Bos taurus	96.64	0.00e+00	4486.00
IUUC-Cel-018165	Caenorhabditis elegans	35.24	3.00e-68	255.00
IUUC-Cja-019858	Callithrix jacchus	96.55	0.00e+00	4464.00
IUUC-Cfa-020973	Canis familiaris	96.78	0.00e+00	4492.00
IUUC-Cpo-022108	Cavia porcellus	92.99	0.00e+00	1815.00
IUUC-Csa-023985	Chlorocebus sabaeus	96.43	0.00e+00	4516.00
IUUC-Cho-025034	Choloepus hoffmanni	88.75	0.00e+00	982.00
IUUC-Cin-025715	Ciona intestinalis	39.67	0.00e+00	916.00
IUUC-Csv-026088	Ciona savignyi	39.58	3.00e-148	518.00
IUUC-Dre-027730	Danio rerio	87.28	0.00e+00	3973.00
IUUC-Dno-029123	Dasypus novemcinctus	95.14	0.00e+00	4394.00
IUUC-Dor-030757	Dipodomys ordii	91.27	0.00e+00	2759.00
IUUC-Dme-032192	Drosophila melanogaster	51.67	6.00e-173	602.00
IUUC-Ete-032292	Echinops telfairi	91.53	0.00e+00	2065.00
IUUC-Eca-034347	Equus caballus	96.36	0.00e+00	4400.00
IUUC-Eeu-034873	Erinaceus europaeus	92.01	0.00e+00	4211.00
IUUC-Fca-036485	Felis catus	95.26	0.00e+00	4340.00
IUUC-Fal-037071	Ficedula albicollis	97.62	0.00e+00	4462.00
IUUC-Gmo-039589	Gadus morhua	87.75	0.00e+00	3919.00
IUUC-Gac-042538	Gasterosteus aculeatus	87.15	0.00e+00	3932.00
IUUC-Ggo-045351	Gorilla gorilla	95.65	0.00e+00	4493.00
IUUC-Hsa-045941	Homo sapiens	96.53	0.00e+00	4530.00
IUUC-Itr-048635	Ictidomys tridecemlineatus	96.40	0.00e+00	4435.00
IUUC-Lch-050480	Latimeria chalumnae	93.01	0.00e+00	4229.00
IUUC-Loc-052664	Lepisosteus oculatus	89.04	0.00e+00	4066.00
IUUC-Laf-053960	Loxodonta africana	95.94	0.00e+00	1542.00
IUUC-Mcc-054703	Macaca mulatta	96.43	0.00e+00	4517.00
IUUC-Meu-056431	Macropus eugenii	83.95	0.00e+00	719.00
IUUC-Mga-059289	Meleagris gallopavo	97.34	0.00e+00	3571.00
IUUC-Mmr-061737	Microcebus murinus	96.15	0.00e+00	4373.00
IUUC-Mdo-062499	Monodelphis domestica	96.76	0.00e+00	4418.00
IUUC-Mmu-063273	Mus musculus	95.46	0.00e+00	4388.00
IUUC-Mpu-066907	Mustela putorius furo	96.39	0.00e+00	4093.00
IUUC-Mlu-067942	Myotis lucifugus	96.12	0.00e+00	4449.00
IUUC-Nle-069527	Nomascus leucogenys	96.51	0.00e+00	4492.00
IUUC-Opr-070626	Ochotona princeps	81.48	0.00e+00	1328.00
IUUC-Ont-071951	Oreochromis niloticus	86.72	0.00e+00	3906.00
IUUC-Oan-072958	Ornithorhynchus anatinus	96.67	0.00e+00	4085.00
IUUC-Ocu-074503	Oryctolagus cuniculus	93.93	0.00e+00	4370.00
IUUC-Ola-086757	Oryzias latipes	87.86	0.00e+00	4011.00
IUUC-Oga-088781	Otolemur garnettii	96.43	0.00e+00	4473.00
IUUC-Oar-089274	Ovis aries	96.33	0.00e+00	4426.00
IUUC-Ptr-090669	Pan troglodytes	96.09	0.00e+00	3893.00
IUUC-Pan-092226	Papio anubis	96.43	0.00e+00	4487.00
IUUC-Psi-093502	Pelodiscus sinensis	97.38	0.00e+00	4444.00
IUUC-Pma-094454	Petromyzon marinus	71.83	0.00e+00	659.00
IUUC-Pfo-096173	Poecilia formosa	87.40	0.00e+00	3684.00
IUUC-Pab-098355	Pongo abelii	96.03	0.00e+00	3067.00
IUUC-Pca-100570	Procavia capensis	91.33	0.00e+00	1070.00
IUUC-Pva-102572	Pteropus vampyrus	89.23	0.00e+00	1251.00
IUUC-Rno-104916	Rattus norvegicus	93.55	0.00e+00	3828.00
IUUC-Sha-106653	Sarcophilus harrisii	96.90	0.00e+00	4463.00
IUUC-Sar-113517	Sorex araneus	90.25	0.00e+00	1270.00
IUUC-Ssc-115470	Sus scrofa	95.75	0.00e+00	2427.00
IUUC-Tgu-116932	Taeniopygia guttata	97.34	0.00e+00	4443.00
IUUC-Tru-117682	Takifugu rubripes	86.63	0.00e+00	2516.00
IUUC-Tsy-119417	Tarsius syrichta	91.30	0.00e+00	2365.00
IUUC-Tni-120442	Tetraodon nigroviridis	83.57	0.00e+00	3574.00
IUUC-Tbe-127456	Tupaia belangeri	82.65	0.00e+00	1988.00
IUUC-Ttr-128606	Tursiops truncatus	93.80	0.00e+00	1559.00
IUUC-Vpa-130112	Vicugna pacos	93.62	0.00e+00	3622.00
IUUC-Xtr-131929	Xenopus tropicalis	93.04	0.00e+00	4364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence