iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072902

UUCD1 version

UUC-OrA-00241

Ensembl Protein ID

ENSOANP00000009574.2

UniProt Accession

F6W0M3; F6W0M3_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006018.2	ENSOANT00000009576.2	ENSOANP00000009574.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.20e-19	68.2	210	277
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.50e-07	28.7	309	335

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 210  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 277
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 309  PSNCLGIRAFADAQGCIELMKVAHSYT 335
           89***********************95 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSGSARKDFD VKHILRLRWK LFSHPSSSPG GPAGGGCLQR DGGAGFEHWG PSQSRLLKSQ 60
ERGSQDGGRG VFWKKPSAAS SSSPASSSSS SSCSPLDGTP GQGQGQPPPP PRTIFYVETL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGGCT CGGCCAGGAA AGACTTCGAT GTGAAGCACA TCCTGCGGCT CCGCTGGAAA 60
CTCTTCAGCC ACCCTTCCTC GTCGCCGTCC TCGCCCTGCG CCGCCTGCTC GTCCTCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024648	Choloepus hoffmanni	83.91	0.00e+00	822.00
IUUC-Dor-030497	Dipodomys ordii	82.58	0.00e+00	786.00
IUUC-Eeu-035121	Erinaceus europaeus	70.00	4.00e-92	331.00
IUUC-Rno-105900	Rattus norvegicus	77.24	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence