iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012327

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box/LRR-repeat protein 8; F-box and leucine-rich repeat protein 8

Genbank Nucleotide ID

BC123762

Gene Name

FBXL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000023632.3	ENSBTAT00000032340.3	ENSBTAP00000032274.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	7.60e-06	26.2	5	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 103  ldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           +++lpee+l  i+++l+ ++  +aarvcr w  +a  +a+w++ 
   Q: 5    GEQLPEEVLALIFRHLPLPDRAAAARVCRAWAAAATCSAVWHDT 48
           789*****************************99999****975 PP

Organism

Bos taurus

Functional Description
(View)

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Protein Sequence
(Fasta)

MAEPGEQLPE EVLALIFRHL PLPDRAAAAR VCRAWAAAAT CSAVWHDTSI SCDCELEGML 60
PPYLSACLDH VQNLWLEFEP SRKSSRRAAT DLLTALTGRT PGLRGLCLEC RGEKPLFDAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGAACCG CACCGCGCCT GTGCTCCTGA GTCAGGACCC GCCTCGGCTC CTGCCGGCAA 60
CGGAAAGCCC ACCCACCCTC TGCACTAACC TGGCCGCCTG GGCCCGGCCT GGATTCCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

KEGG

bta:614765

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019275	Callithrix jacchus	82.89	9.00e-122	429.00
IUUC-Cin-025430	Ciona intestinalis	24.35	8.00e-16	77.80
IUUC-Dor-030117	Dipodomys ordii	81.40	4.00e-140	490.00
IUUC-Eeu-034813	Erinaceus europaeus	86.36	1.00e-48	187.00
IUUC-Fca-035409	Felis catus	80.53	7.00e-59	219.00
IUUC-Gga-041226	Gallus gallus	40.76	6.00e-70	257.00
IUUC-Hsa-046153	Homo sapiens	92.00	4.00e-06	43.50
IUUC-Mcc-054642	Macaca mulatta	90.00	4.00e-10	55.50
IUUC-Mga-059266	Meleagris gallopavo	40.49	3.00e-69	255.00
IUUC-Mmu-063155	Mus musculus	70.00	3.00e-05	39.30
IUUC-Ocu-074339	Oryctolagus cuniculus	82.35	2.00e-127	448.00
IUUC-Oga-089027	Otolemur garnettii	80.95	6.00e-128	450.00
IUUC-Psi-093260	Pelodiscus sinensis	40.11	7.00e-78	283.00
IUUC-Pva-102347	Pteropus vampyrus	81.21	7.00e-99	353.00
IUUC-Sar-113473	Sorex araneus	81.82	2.00e-120	425.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence