iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000007151.5	ENSGALT00000060609.1	ENSGALP00000046307.1
ENSGALG00000007151.5	ENSGALT00000011586.5	ENSGALP00000011572.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-29	99.6	307	345
UBD/Beta-Prp	6.00e-53	180.3	409	668

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll 
   Q: 307  GHLSSVYCIAFdrSGRRIFTGSDDCLVKIWATDDGRLLS 345
           8**********96669******************99875 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v+++
   Q: 409  TRYLTSTGADGTICFWQWHANTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKMAELESHTDKVVAV 497
           689***************997776677764444444444449************************88888****************** PP
   S: 101  sfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           +f+ +g   ++vsGs+d t+rvw+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W+++tg+l
   Q: 498  QFCNNGdsLRFVSGSRDGTARVWQYHQQEWKSVvldmatkmtgnnvasgEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQL 586
           ****8832468**************9999998899**********8888888888899******************************* PP
   S: 172  lrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           l+ l+g h+d v  l+   fd+  + ++s+++dg + +wd+ +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 587  LHSLSG-HDDEVFVLEahpFDQ--RIVLSAGHDGNIFIWDIDKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 668
           *****9.*********554544..8999******************988877554555577777899999999999998887765 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MATAAAPTQL EAELYYLIAR FLQSGPCKKS AQVSGAAGRA GREGKGRDGE RSREGKQKGR 60
GRTAAGGLGL GGARRCAAGS GLTSFVCVLC VSPGAGGGAG GAPGKGRRCP ARPGPSRHCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACAG CGGCCGCCCC GACCCAGCTG GAAGCCGGTG GGTAGCGCTG GCCGCGGGGG 60
CTCCGCCGCT GTCCGCCCGC TTTGTAACCG TGTCCCCTTC TCCCGTTCCC CTCCCTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	82.75	0.00e+00	2518.00
IUUC-Apl-004016	Anas platyrhynchos	93.65	0.00e+00	2564.00
IUUC-Aca-004722	Anolis carolinensis	88.40	0.00e+00	2383.00
IUUC-Ame-010602	Astyanax mexicanus	68.96	0.00e+00	1880.00
IUUC-Bta-013198	Bos taurus	80.89	0.00e+00	2337.00
IUUC-Cfa-020963	Canis familiaris	82.56	0.00e+00	2511.00
IUUC-Cpo-022448	Cavia porcellus	78.24	0.00e+00	2358.00
IUUC-Csa-023166	Chlorocebus sabaeus	83.07	0.00e+00	2493.00
IUUC-Cin-025553	Ciona intestinalis	42.31	8.00e-120	424.00
IUUC-Csv-025813	Ciona savignyi	44.86	0.00e+00	637.00
IUUC-Dre-028508	Danio rerio	68.08	0.00e+00	1868.00
IUUC-Dno-030070	Dasypus novemcinctus	80.97	0.00e+00	2400.00
IUUC-Dor-031052	Dipodomys ordii	74.45	0.00e+00	1078.00
IUUC-Ete-032650	Echinops telfairi	78.14	0.00e+00	1632.00
IUUC-Eca-033953	Equus caballus	83.60	0.00e+00	2312.00
IUUC-Eeu-034871	Erinaceus europaeus	75.32	0.00e+00	1179.00
IUUC-Fca-036099	Felis catus	82.51	0.00e+00	2501.00
IUUC-Fal-037246	Ficedula albicollis	96.19	0.00e+00	2746.00
IUUC-Gmo-039116	Gadus morhua	67.37	9.00e-163	568.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.47	0.00e+00	1793.00
IUUC-Ggo-045500	Gorilla gorilla	64.87	0.00e+00	1818.00
IUUC-Hsa-045666	Homo sapiens	83.07	0.00e+00	2496.00
IUUC-Lch-050646	Latimeria chalumnae	63.46	0.00e+00	1821.00
IUUC-Loc-051802	Lepisosteus oculatus	71.46	0.00e+00	2080.00
IUUC-Laf-053942	Loxodonta africana	83.13	0.00e+00	2536.00
IUUC-Mcc-054645	Macaca mulatta	83.20	0.00e+00	2498.00
IUUC-Meu-056321	Macropus eugenii	73.29	0.00e+00	1095.00
IUUC-Mga-060063	Meleagris gallopavo	97.76	0.00e+00	2845.00
IUUC-Mmr-061262	Microcebus murinus	83.53	0.00e+00	2526.00
IUUC-Mdo-062320	Monodelphis domestica	74.12	0.00e+00	2207.00
IUUC-Mmu-063163	Mus musculus	82.81	0.00e+00	2479.00
IUUC-Mpu-066628	Mustela putorius furo	82.21	0.00e+00	2525.00
IUUC-Mlu-068082	Myotis lucifugus	82.27	0.00e+00	2460.00
IUUC-Nle-069609	Nomascus leucogenys	83.20	0.00e+00	2507.00
IUUC-Ont-071589	Oreochromis niloticus	67.63	0.00e+00	1796.00
IUUC-Oan-072954	Ornithorhynchus anatinus	65.02	0.00e+00	1814.00
IUUC-Ocu-074122	Oryctolagus cuniculus	83.07	0.00e+00	1835.00
IUUC-Ogu-078641	Oryza glumaepatula	30.82	8.00e-49	189.00
IUUC-Ola-086580	Oryzias latipes	66.40	0.00e+00	1829.00
IUUC-Oga-089053	Otolemur garnettii	83.28	0.00e+00	2502.00
IUUC-Oar-090042	Ovis aries	81.60	0.00e+00	2504.00
IUUC-Ptr-091268	Pan troglodytes	82.84	0.00e+00	2450.00
IUUC-Pan-092376	Papio anubis	83.20	0.00e+00	2498.00
IUUC-Psi-093408	Pelodiscus sinensis	90.45	0.00e+00	2713.00
IUUC-Pfo-096515	Poecilia formosa	66.74	0.00e+00	1751.00
IUUC-Pab-097672	Pongo abelii	81.20	0.00e+00	2459.00
IUUC-Pva-102512	Pteropus vampyrus	87.73	0.00e+00	2088.00
IUUC-Rno-105797	Rattus norvegicus	82.49	0.00e+00	2464.00
IUUC-Sha-107061	Sarcophilus harrisii	74.43	0.00e+00	2367.00
IUUC-Sar-113004	Sorex araneus	68.28	0.00e+00	1221.00
IUUC-Tgu-117254	Taeniopygia guttata	94.47	0.00e+00	2724.00
IUUC-Tru-118186	Takifugu rubripes	65.86	0.00e+00	1772.00
IUUC-Tsy-119003	Tarsius syrichta	78.74	0.00e+00	2308.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.49	0.00e+00	1755.00
IUUC-Ttr-129265	Tursiops truncatus	82.71	0.00e+00	2425.00
IUUC-Vpa-130736	Vicugna pacos	73.95	0.00e+00	1186.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence