iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045356

Ensembl Protein ID

ENSGGOP00000010455.2

UniProt Accession

G3R585; G3R585_GORGO

Protein Name

Uncharacterized protein

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010703.2	ENSGGOT00000023397.1	ENSGGOP00000017224.1
ENSGGOG00000010703.2	ENSGGOT00000023829.1	ENSGGOP00000027857.1
ENSGGOG00000010703.2	ENSGGOT00000010763.2	ENSGGOP00000010455.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-12	47.4	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MRAVLTWRDK AEHCINDIAF KPDGTQLILA AGSRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY TSWSVMSSLH LHLTFLGLHK TVRVTATNKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCTTTTG CTGCTTTTCT CGCTTTCCCT TTCGGACATG CGCGCTCGGA GCAAGGCGCC 60
CTCGCACTTA GCTTACCGCG CATGTACGTT GCCAGGGGTA ACGCAGGTAG CCAAAGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	88.78	0.00e+00	2229.00
IUUC-Apl-003504	Anas platyrhynchos	85.41	0.00e+00	1754.00
IUUC-Aca-004767	Anolis carolinensis	80.06	0.00e+00	2066.00
IUUC-Ame-011642	Astyanax mexicanus	70.95	0.00e+00	1845.00
IUUC-Bta-012969	Bos taurus	86.43	0.00e+00	2169.00
IUUC-Cel-018670	Caenorhabditis elegans	36.53	0.00e+00	853.00
IUUC-Cja-019249	Callithrix jacchus	87.77	0.00e+00	2201.00
IUUC-Cfa-020915	Canis familiaris	89.24	0.00e+00	2201.00
IUUC-Cpo-021888	Cavia porcellus	88.00	0.00e+00	1803.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	46.55	0.00e+00	1085.00
IUUC-Csa-023533	Chlorocebus sabaeus	94.34	0.00e+00	2387.00
IUUC-Cin-025121	Ciona intestinalis	54.89	0.00e+00	1456.00
IUUC-Csv-026240	Ciona savignyi	55.78	0.00e+00	1401.00
IUUC-Dno-029685	Dasypus novemcinctus	78.31	0.00e+00	1936.00
IUUC-Dme-032005	Drosophila melanogaster	26.74	6.00e-09	57.00
IUUC-Ete-032682	Echinops telfairi	82.66	0.00e+00	1637.00
IUUC-Eca-033831	Equus caballus	89.07	0.00e+00	2277.00
IUUC-Eeu-034919	Erinaceus europaeus	83.02	0.00e+00	977.00
IUUC-Fca-036559	Felis catus	88.68	0.00e+00	2263.00
IUUC-Fal-037340	Ficedula albicollis	83.27	0.00e+00	1687.00
IUUC-Gga-040595	Gallus gallus	84.99	0.00e+00	1748.00
IUUC-Hsa-046135	Homo sapiens	99.23	0.00e+00	2538.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	82.65	0.00e+00	1992.00
IUUC-Lch-050183	Latimeria chalumnae	79.77	0.00e+00	1131.00
IUUC-Loc-052049	Lepisosteus oculatus	75.42	0.00e+00	1959.00
IUUC-Laf-053728	Loxodonta africana	87.93	0.00e+00	2253.00
IUUC-Mcc-054971	Macaca mulatta	97.36	0.00e+00	2481.00
IUUC-Meu-056446	Macropus eugenii	82.28	0.00e+00	2088.00
IUUC-Mga-059296	Meleagris gallopavo	79.46	0.00e+00	2047.00
IUUC-Mmr-061232	Microcebus murinus	88.99	0.00e+00	2237.00
IUUC-Mdo-062115	Monodelphis domestica	86.73	0.00e+00	2216.00
IUUC-Mmu-063664	Mus musculus	87.60	0.00e+00	2276.00
IUUC-Mpu-066136	Mustela putorius furo	85.05	0.00e+00	2149.00
IUUC-Mlu-068238	Myotis lucifugus	85.58	0.00e+00	2198.00
IUUC-Nle-069003	Nomascus leucogenys	91.80	0.00e+00	2301.00
IUUC-Ont-072080	Oreochromis niloticus	71.71	0.00e+00	1883.00
IUUC-Oan-072891	Ornithorhynchus anatinus	75.08	0.00e+00	878.00
IUUC-Ocu-074262	Oryctolagus cuniculus	85.98	0.00e+00	2169.00
IUUC-Ola-086538	Oryzias latipes	70.62	0.00e+00	1816.00
IUUC-Oga-088722	Otolemur garnettii	89.62	0.00e+00	2218.00
IUUC-Oar-089249	Ovis aries	77.85	0.00e+00	1912.00
IUUC-Ptr-090752	Pan troglodytes	97.76	0.00e+00	2484.00
IUUC-Pan-092472	Papio anubis	94.50	0.00e+00	2388.00
IUUC-Psi-093335	Pelodiscus sinensis	79.44	0.00e+00	2050.00
IUUC-Pma-094520	Petromyzon marinus	67.39	0.00e+00	1585.00
IUUC-Ppa-095600	Physcomitrella patens	45.40	2.00e-32	131.00
IUUC-Pfo-096526	Poecilia formosa	68.90	0.00e+00	1761.00
IUUC-Pab-098428	Pongo abelii	98.12	0.00e+00	1234.00
IUUC-Pca-100233	Procavia capensis	71.45	0.00e+00	967.00
IUUC-Pva-103064	Pteropus vampyrus	80.31	0.00e+00	1958.00
IUUC-Rno-105764	Rattus norvegicus	87.83	0.00e+00	2246.00
IUUC-Sha-106649	Sarcophilus harrisii	86.02	0.00e+00	2183.00
IUUC-Smo-109287	Selaginella moellendorffii	38.70	0.00e+00	857.00
IUUC-Tgu-116870	Taeniopygia guttata	78.46	0.00e+00	1968.00
IUUC-Tru-118661	Takifugu rubripes	69.37	0.00e+00	1781.00
IUUC-Tsy-119640	Tarsius syrichta	93.03	3.00e-110	393.00
IUUC-Tni-120812	Tetraodon nigroviridis	68.54	0.00e+00	1761.00
IUUC-Ttr-128862	Tursiops truncatus	88.35	0.00e+00	2264.00
IUUC-Vpa-130049	Vicugna pacos	85.59	2.00e-151	530.00
IUUC-Xtr-131914	Xenopus tropicalis	74.27	0.00e+00	1924.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence