iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ogu-078620

Ensembl Protein ID

OGLUM11G00210.1

UniProt Accession

A0A0E0BEE2; A0A0E0BEE2_9ORYZ

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OGLUM11G00210	OGLUM11G00210.1	OGLUM11G00210.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.30e-123	413.1	195	682

Active Site

Position(s)	Description	Evidence
376	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           YD Qi ++G++ q+kl++ak+++vG g+lGcE+lKnL+l+G+     g++tv+D+d +e+snl+rqFLfr++++g++K+ vaa a+  +np+ +
   Q: 195  YDAQISVFGSNLQKKLEQAKIFMVGSGALGCEFLKNLALMGIscnqnGKLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMAINPKLH 288
           ********************************************************************************************** PP
   S: 90   veaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketp 180
           vea +++ ++++e+++   F + +d Vv+aldn+ ar++++++c++ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p
   Q: 289  VEALQNRASPETENVFndaFWESLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFP 382
           **************9999**************************************************************************** PP
   S: 181  naaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfec 262
            +++h+++wa              +n +l++  g  +v+     ++ ++ +++v + l+ e+ e+f+++i++a+ +f+ +++n +kql+  f+ 
   Q: 383  HNIDHCLTWArsefegllektpTEVNAFLSNPGGYATVARTAGDAQARDQLERVIECLEREKCETFQDCITWARLKFEDYFSNRVKQLTYTFPE 476
           *********************9999********************************************************************* PP
   S: 263  divtkskspfwv..........................................................sfcsnaealqvpekvekdeevvka 298
           d +t+s++pfw+                                                            +++  ++ ++ek+++   ++ +
   Q: 477  DAMTSSGAPFWSapkrfprplefstsdpsqlnfilaaailraetfgipipdwvknpakmaeavdkvivpdFQPKQGVKIVTDEKATSLSSASVD 570
           **************************************************99999997777777765553333333444444555555444444 PP
   S: 299  sap.lylllralerfek..kkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKv 387
           +a+ ++ l+++le  +k  ++g +++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv
   Q: 571  DAAvIEELIAKLEAISKtlQPGFQMKPIQFEKDDDTnyHMDVIAGFANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKV 663
           444899999999999985579*************************************.*********************************** PP
   S: 388  vsg..kfeplknfflfdae 404
           + g  k e ++n+f ++a+
   Q: 664  LGGghKVEDYRNTFANLAI 682
           ***999********99876 PP

Organism

Oryza glumaepatula

Protein Sequence
(Fasta)

MSELNDGKPR KIKNARPYSF TLEEDTTSYG TYVRGGIVTQ VKPPKVLKFK TLKDAIKEPG 60
EFLMSDFSKF DRPPLLHLAF QALDKFRNDL RRFPIAGSSD DVQRLIDFAI SINESLGDSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTATTGCA TATTTTCTTA TTCTTGGAAT AACCATTTCC ATGTGAACAT ACAGGCTGTG 60
GTCTTTACTG ATATCAGCTT AGAGAAAGCA GTTGAGTTTG ACAGTTACTG CCACAACCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR023366--ATP_synth_asu-like
IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-032514	Echinops telfairi	33.91	1.00e-100	361.00
IUUC-Eeu-034717	Erinaceus europaeus	34.74	9.00e-103	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence