iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117895

UUCD1 version

UUC-TaR-00470

Ensembl Protein ID

ENSTRUP00000022853.1

UniProt Accession

H2TDW1; H2TDW1_TAKRU

Protein Name

Uncharacterized protein

Gene Name

brca1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009091.1	ENSTRUT00000022946.1	ENSTRUP00000022851.1
ENSTRUG00000009091.1	ENSTRUT00000022947.1	ENSTRUP00000022852.1
ENSTRUG00000009091.1	ENSTRUT00000022948.1	ENSTRUP00000022853.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.40e-08	34.8	22	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ +   p+++ C H+f++ C+ k+  l+n ++++++CP+C+
   Q: 22   CPICLDILTA-PVSTKCDHQFCKFCISKL--LSNTKQNKANCPVCK 64
           ********99.***************999..8999**********7 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MEAAKAADVK KGISVLWESL QCPICLDILT APVSTKCDHQ FCKFCISKLL SNTKQNKANC 60
PVCKSKITKR SLQESPGFQR LVTGLQGMIL AYENDTGTNY FTGLSRQTQQ PHVADIKNAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACCATGG AAGCAGCAAA AGCCGCAGAT GTTAAGAAAG GGATTTCAGT GCTTTGGGAG 60
AGTCTACAGT GTCCAATATG GTGACTAATA TTCCATTGAA TTTTATATCT GGTAACATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011364--BRCA1
IPR031099--BRCA1-associated
IPR001357--BRCT_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50172--BRCT
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00533--BRCT

SMART

SM00292--BRCT
SM00184--RING

Gene Ontology

GO:0070531--C:BRCA1-A complex
GO:0031436--C:BRCA1-BARD1 complex
GO:0005886--C:plasma membrane
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043009--P:chordate embryonic development
GO:0000724--P:double-strand break repair via homologous recombination
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0035067--P:negative regulation of histone acetylation
GO:0071158--P:positive regulation of cell cycle arrest
GO:0035066--P:positive regulation of histone acetylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000225	Aegilops tauschii	30.51	1.00e-17	85.90
IUUC-Aml-002388	Ailuropoda melanoleuca	42.98	9.00e-54	206.00
IUUC-Atr-002625	Amborella trichopoda	24.89	2.00e-18	88.60
IUUC-Apl-003252	Anas platyrhynchos	50.97	7.00e-60	226.00
IUUC-Aca-004526	Anolis carolinensis	46.34	1.00e-50	194.00
IUUC-Ath-006986	Arabidopsis thaliana	29.08	1.00e-16	82.40
IUUC-Ago-007781	Ashbya gossypii	48.21	5.00e-12	65.50
IUUC-Ame-011720	Astyanax mexicanus	33.29	3.00e-86	313.00
IUUC-Bta-013433	Bos taurus	45.97	5.00e-54	207.00
IUUC-Bdi-014760	Brachypodium distachyon	26.67	6.00e-19	90.10
IUUC-Bol-016476	Brassica oleracea	27.59	2.00e-19	91.30
IUUC-Bra-017176	Brassica rapa	26.76	3.00e-19	90.90
IUUC-Cja-019149	Callithrix jacchus	42.17	7.00e-52	200.00
IUUC-Cfa-020322	Canis familiaris	39.45	6.00e-53	203.00
IUUC-Cpo-021583	Cavia porcellus	44.66	5.00e-50	194.00
IUUC-Cre-022955	Chlamydomonas reinhardtii	26.97	1.00e-09	59.30
IUUC-Csa-024227	Chlorocebus sabaeus	54.70	3.00e-32	133.00
IUUC-Cho-024530	Choloepus hoffmanni	49.33	2.00e-43	172.00
IUUC-Cin-025364	Ciona intestinalis	35.63	2.00e-12	66.20
IUUC-Csv-026245	Ciona savignyi	34.94	5.00e-12	64.30
IUUC-Dno-029247	Dasypus novemcinctus	52.94	3.00e-17	85.10
IUUC-Ete-032472	Echinops telfairi	33.45	4.00e-37	150.00
IUUC-Eca-033446	Equus caballus	46.23	1.00e-52	202.00
IUUC-Eeu-034858	Erinaceus europaeus	51.72	2.00e-30	129.00
IUUC-Fca-035991	Felis catus	42.80	8.00e-54	206.00
IUUC-Fal-036803	Ficedula albicollis	48.54	1.00e-56	216.00
IUUC-Gmo-038782	Gadus morhua	65.78	6.00e-72	266.00
IUUC-Ggr-039833	Gaeumannomyces graminis	40.00	3.00e-07	50.10
IUUC-Gga-040969	Gallus gallus	48.86	1.00e-59	226.00
IUUC-Gac-042296	Gasterosteus aculeatus	43.96	9.00e-161	561.00
IUUC-Ggo-044740	Gorilla gorilla	40.24	1.00e-45	179.00
IUUC-Hsa-046086	Homo sapiens	42.74	1.00e-49	192.00
IUUC-Itr-048512	Ictidomys tridecemlineatus	42.63	6.00e-52	200.00
IUUC-Lch-049789	Latimeria chalumnae	47.87	1.00e-59	225.00
IUUC-Lpe-050895	Leersia perrieri	28.26	6.00e-19	89.70
IUUC-Loc-051952	Lepisosteus oculatus	29.73	6.00e-119	422.00
IUUC-Laf-053648	Loxodonta africana	47.42	5.00e-55	210.00
IUUC-Mcc-055210	Macaca mulatta	46.45	5.00e-54	207.00
IUUC-Meu-056342	Macropus eugenii	39.75	3.00e-24	108.00
IUUC-Mtr-058400	Medicago truncatula	28.93	2.00e-16	81.60
IUUC-Mga-060163	Meleagris gallopavo	48.40	4.00e-59	224.00
IUUC-Mdo-062209	Monodelphis domestica	46.70	2.00e-53	204.00
IUUC-Mmu-064003	Mus musculus	40.57	2.00e-44	175.00
IUUC-Mac-065131	Musa acuminata	26.64	8.00e-18	86.30
IUUC-Mpu-065825	Mustela putorius furo	42.80	4.00e-54	206.00
IUUC-Mlu-068176	Myotis lucifugus	41.63	5.00e-48	187.00
IUUC-Nle-069178	Nomascus leucogenys	39.64	2.00e-49	192.00
IUUC-Opr-070574	Ochotona princeps	36.49	2.00e-35	145.00
IUUC-Ont-072380	Oreochromis niloticus	46.11	0.00e+00	959.00
IUUC-Oan-073243	Ornithorhynchus anatinus	40.57	1.00e-19	88.60
IUUC-Ocu-074424	Oryctolagus cuniculus	38.41	3.00e-51	197.00
IUUC-Oba-075676	Oryza barthii	26.77	4.00e-13	70.50
IUUC-Obr-076308	Oryza brachyantha	24.69	4.00e-17	84.00
IUUC-Ogl-077654	Oryza glaberrima	26.77	4.00e-13	70.50
IUUC-Ogu-078659	Oryza glumaepatula	26.77	4.00e-13	70.50
IUUC-Oin-079086	Oryza indica	26.77	4.00e-13	70.90
IUUC-Olo-080264	Oryza longistaminata	26.77	1.00e-12	69.70
IUUC-Ome-081445	Oryza meridionalis	24.27	1.00e-14	75.50
IUUC-Oni-082502	Oryza nivara	26.77	4.00e-13	70.90
IUUC-Opu-083700	Oryza punctata	27.78	4.00e-16	80.50
IUUC-Oru-085093	Oryza rufipogon	26.77	4.00e-13	70.50
IUUC-Osa-086087	Oryza sativa	26.77	4.00e-13	70.90
IUUC-Ola-086863	Oryzias latipes	57.99	5.00e-111	396.00
IUUC-Oar-089938	Ovis aries	45.97	8.00e-54	206.00
IUUC-Ptr-090960	Pan troglodytes	42.74	1.00e-49	192.00
IUUC-Pan-092609	Papio anubis	51.14	1.00e-23	106.00
IUUC-Pfo-096328	Poecilia formosa	44.47	0.00e+00	833.00
IUUC-Pab-097982	Pongo abelii	42.34	6.00e-49	190.00
IUUC-Pop-099956	Populus trichocarpa	27.56	1.00e-18	89.00
IUUC-Pca-100698	Procavia capensis	42.11	2.00e-53	205.00
IUUC-Ppe-101676	Prunus persica	25.11	6.00e-17	83.20
IUUC-Pva-102631	Pteropus vampyrus	42.08	1.00e-48	189.00
IUUC-Rno-105879	Rattus norvegicus	37.97	1.00e-43	172.00
IUUC-Sha-106701	Sarcophilus harrisii	54.05	1.00e-19	92.40
IUUC-Sit-110609	Setaria italica	30.77	3.00e-17	84.30
IUUC-Sar-113047	Sorex araneus	56.00	5.00e-18	87.80
IUUC-Sbi-114470	Sorghum bicolor	26.25	1.00e-18	89.00
IUUC-Ssc-115846	Sus scrofa	46.38	2.00e-48	188.00
IUUC-Tgu-116785	Taeniopygia guttata	37.26	1.00e-56	215.00
IUUC-Tsy-118885	Tarsius syrichta	53.33	4.00e-17	84.70
IUUC-Tni-119654	Tetraodon nigroviridis	66.74	0.00e+00	1526.00
IUUC-Tca-121809	Theobroma cacao	30.36	4.00e-20	93.20
IUUC-Tae-124838	Triticum aestivum	31.95	5.00e-18	87.00
IUUC-Tur-126725	Triticum urartu	31.95	4.00e-18	87.00
IUUC-Tbe-127421	Tupaia belangeri	34.54	1.00e-32	135.00
IUUC-Ttr-128685	Tursiops truncatus	44.86	7.00e-49	190.00
IUUC-Vpa-130216	Vicugna pacos	40.93	7.00e-54	206.00
IUUC-Vvi-131586	Vitis vinifera	34.74	6.00e-15	77.00
IUUC-Xtr-132398	Xenopus tropicalis	43.32	5.00e-51	197.00
IUUC-Xma-133651	Xiphophorus maculatus	43.51	0.00e+00	762.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence