iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133695

Ensembl Protein ID

ENSXMAP00000008149.1

UniProt Accession

M4A105; M4A105_XIPMA

Genbank Protein ID

ENSXMAP00000008149

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AGAJ01033347

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008116.1	ENSXMAT00000008159.1	ENSXMAP00000008149.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.40e-17	62.4	811	851

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 811  WCFVCSKGGQ----LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCR 851
           8*********....*******************....9***8.******8 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

LQFHLKKAAI LKRICQSGII MKQPPESLST LKGRADMGSD PALLMDKAAA QLAATLQDGV 60
LQKMSGHNHS HERLKDLTSL VLNGDQDALP KLCTPEPPML KGDEAPATND AHQHNRTPHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACAGTTCC ACCTTAAAAA AGCAGCCATT TTAAAGAGGA TCTGCCAATC AGGCATCATG 60
TCTGATCAAA GAAGAATTAG CCTGTTGTGT TTGAAAGGGC CAATATTATG GAAAATTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	52.39	0.00e+00	1209.00
IUUC-Apl-003677	Anas platyrhynchos	50.79	0.00e+00	1225.00
IUUC-Aca-004278	Anolis carolinensis	68.09	0.00e+00	1051.00
IUUC-Ame-011932	Astyanax mexicanus	74.03	0.00e+00	1118.00
IUUC-Bta-012522	Bos taurus	50.85	0.00e+00	1189.00
IUUC-Bra-017864	Brassica rapa	34.38	1.00e-12	70.10
IUUC-Cja-018908	Callithrix jacchus	50.15	0.00e+00	1209.00
IUUC-Cfa-020894	Canis familiaris	51.62	0.00e+00	1226.00
IUUC-Cpo-021982	Cavia porcellus	51.06	0.00e+00	1220.00
IUUC-Csa-023807	Chlorocebus sabaeus	50.19	0.00e+00	1210.00
IUUC-Dre-027492	Danio rerio	80.64	0.00e+00	1149.00
IUUC-Dor-031103	Dipodomys ordii	67.91	0.00e+00	895.00
IUUC-Dme-032193	Drosophila melanogaster	37.05	5.00e-118	419.00
IUUC-Ete-032488	Echinops telfairi	47.98	0.00e+00	1095.00
IUUC-Eca-034066	Equus caballus	50.99	0.00e+00	1222.00
IUUC-Eeu-035199	Erinaceus europaeus	44.44	5.00e-116	412.00
IUUC-Fca-035434	Felis catus	53.36	0.00e+00	1108.00
IUUC-Fal-037113	Ficedula albicollis	50.78	0.00e+00	1241.00
IUUC-Gmo-039686	Gadus morhua	80.46	0.00e+00	1136.00
IUUC-Gga-040273	Gallus gallus	49.74	0.00e+00	1216.00
IUUC-Gac-042123	Gasterosteus aculeatus	67.11	0.00e+00	1663.00
IUUC-Ggo-044643	Gorilla gorilla	50.50	0.00e+00	1220.00
IUUC-Hsa-046380	Homo sapiens	50.11	0.00e+00	1208.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	71.58	0.00e+00	1004.00
IUUC-Lch-050217	Latimeria chalumnae	50.92	0.00e+00	1204.00
IUUC-Loc-052766	Lepisosteus oculatus	58.79	0.00e+00	1263.00
IUUC-Laf-053780	Loxodonta africana	51.18	0.00e+00	1237.00
IUUC-Mcc-054928	Macaca mulatta	50.72	0.00e+00	1223.00
IUUC-Mga-059576	Meleagris gallopavo	50.72	0.00e+00	1226.00
IUUC-Mmr-061045	Microcebus murinus	50.15	0.00e+00	1211.00
IUUC-Mdo-062576	Monodelphis domestica	50.53	0.00e+00	1202.00
IUUC-Mmu-063640	Mus musculus	50.15	0.00e+00	1204.00
IUUC-Mpu-066512	Mustela putorius furo	51.62	0.00e+00	1208.00
IUUC-Nle-069896	Nomascus leucogenys	49.96	0.00e+00	1175.00
IUUC-Ont-072197	Oreochromis niloticus	67.16	0.00e+00	1679.00
IUUC-Ocu-074758	Oryctolagus cuniculus	50.54	0.00e+00	1182.00
IUUC-Obr-076085	Oryza brachyantha	44.44	1.00e-10	62.80
IUUC-Olo-080702	Oryza longistaminata	41.01	2.00e-44	174.00
IUUC-Opu-083371	Oryza punctata	43.72	2.00e-44	174.00
IUUC-Oar-089736	Ovis aries	74.46	0.00e+00	959.00
IUUC-Ptr-091055	Pan troglodytes	50.19	0.00e+00	1209.00
IUUC-Pan-092752	Papio anubis	74.77	0.00e+00	1018.00
IUUC-Psi-093620	Pelodiscus sinensis	51.69	0.00e+00	1254.00
IUUC-Pfo-097464	Poecilia formosa	84.79	0.00e+00	2019.00
IUUC-Pab-098051	Pongo abelii	50.34	0.00e+00	1212.00
IUUC-Pca-100273	Procavia capensis	52.65	0.00e+00	1195.00
IUUC-Pva-102473	Pteropus vampyrus	69.94	0.00e+00	932.00
IUUC-Rno-105056	Rattus norvegicus	50.61	0.00e+00	1204.00
IUUC-Sha-107494	Sarcophilus harrisii	50.72	0.00e+00	1203.00
IUUC-Sar-113310	Sorex araneus	53.95	0.00e+00	1066.00
IUUC-Sbi-114581	Sorghum bicolor	31.30	1.00e-09	57.40
IUUC-Ssc-116344	Sus scrofa	50.70	0.00e+00	1183.00
IUUC-Tgu-116786	Taeniopygia guttata	51.25	0.00e+00	1235.00
IUUC-Tru-117638	Takifugu rubripes	68.08	0.00e+00	1612.00
IUUC-Tsy-118937	Tarsius syrichta	74.92	0.00e+00	1029.00
IUUC-Tni-120452	Tetraodon nigroviridis	83.53	0.00e+00	1285.00
IUUC-Tae-125237	Triticum aestivum	30.12	6.00e-06	44.70
IUUC-Tbe-127291	Tupaia belangeri	71.27	0.00e+00	974.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence