iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037246

Ensembl Protein ID

ENSFALP00000004241.1

UniProt Accession

U3JN87; U3JN87_FICAL

Genbank Protein ID

ENSFALP00000004241

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021011

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000004071.1	ENSFALT00000004262.1	ENSFALP00000004241.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-29	100.7	142	180
UBD/Beta-Prp	6.70e-53	179.5	244	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll 
   Q: 142  GHLSSVYCIAFdrSGRRIFTGSDDCLVKIWATDDGRLLS 180
           8**********96669******************99875 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v+++
   Q: 244  TRYLTSTGADGTICFWQWHANTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKMAELESHTDKVVAV 332
           589***************997776677764444444444449************************88888****************** PP
   S: 101  sfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           +f+ +g   ++vsGs+d t+r+w+ ++  + +                  +++++  v++v+++  +  ++++ ++  +++W+++tg+l
   Q: 333  QFCNNGdsLRFVSGSRDGTARIWHYHQHDWKSLvldmatkmtgnnvasgEDKVTKLKVTMVAWDRYDATVITAVNNFLLKVWNSSTGQL 421
           ****8832468*************999988877899*********8888888888899******************************* PP
   S: 172  lrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           l+ l+g h+d v  l+   fd+  + ++s+++dg + +wd+ +g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 422  LHSLSG-HDDEVFVLEahpFDQ--RIVLSAGHDGNIFVWDIDKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 503
           *****9.*********554544..8999******************988877554555577778899999999999999887766 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MPVKCAEWRL LLRHKPFGCV SLRKVAVNAH IPPDYLLRIC ERLGPLLDKE IPQSVLGVQT 60
LLGVGRQSLL RAAKDFRHTL WKGSAFAALH RGRPPELPVN YGKPPNVVHI LSARQLTGCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCCCCCCC CCCCCCCCCC CCCCCCCGGC CTGCGGCGGC CTGCGCGAAA CCCGCCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	82.06	0.00e+00	2447.00
IUUC-Apl-004016	Anas platyrhynchos	92.10	0.00e+00	2509.00
IUUC-Aca-004722	Anolis carolinensis	86.55	0.00e+00	2387.00
IUUC-Ame-010602	Astyanax mexicanus	68.54	0.00e+00	1871.00
IUUC-Bta-013198	Bos taurus	80.47	0.00e+00	2309.00
IUUC-Cfa-020963	Canis familiaris	81.99	0.00e+00	2441.00
IUUC-Cpo-022448	Cavia porcellus	76.13	0.00e+00	2307.00
IUUC-Csa-023166	Chlorocebus sabaeus	80.26	0.00e+00	2417.00
IUUC-Cin-025553	Ciona intestinalis	42.12	6.00e-119	421.00
IUUC-Dre-028508	Danio rerio	67.48	0.00e+00	1828.00
IUUC-Dno-030070	Dasypus novemcinctus	77.91	0.00e+00	2331.00
IUUC-Ete-032650	Echinops telfairi	80.69	0.00e+00	1590.00
IUUC-Eca-033953	Equus caballus	81.00	0.00e+00	2278.00
IUUC-Eeu-034871	Erinaceus europaeus	73.94	0.00e+00	1124.00
IUUC-Fca-036099	Felis catus	81.82	0.00e+00	2435.00
IUUC-Gmo-039116	Gadus morhua	66.74	7.00e-161	561.00
IUUC-Gga-041097	Gallus gallus	96.06	0.00e+00	2792.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.22	0.00e+00	1762.00
IUUC-Hsa-045666	Homo sapiens	80.26	0.00e+00	2421.00
IUUC-Loc-051802	Lepisosteus oculatus	71.57	0.00e+00	2055.00
IUUC-Laf-053942	Loxodonta africana	82.04	0.00e+00	2462.00
IUUC-Mcc-054645	Macaca mulatta	80.33	0.00e+00	2420.00
IUUC-Meu-056321	Macropus eugenii	72.77	0.00e+00	1061.00
IUUC-Mga-060063	Meleagris gallopavo	94.54	0.00e+00	2773.00
IUUC-Mmr-061262	Microcebus murinus	80.94	0.00e+00	2450.00
IUUC-Mdo-062320	Monodelphis domestica	74.89	0.00e+00	2138.00
IUUC-Mmu-063163	Mus musculus	79.54	0.00e+00	2414.00
IUUC-Mpu-066628	Mustela putorius furo	81.53	0.00e+00	2453.00
IUUC-Mlu-068082	Myotis lucifugus	81.58	0.00e+00	2392.00
IUUC-Nle-069609	Nomascus leucogenys	80.39	0.00e+00	2433.00
IUUC-Ont-071589	Oreochromis niloticus	64.95	0.00e+00	1773.00
IUUC-Ola-086580	Oryzias latipes	66.79	0.00e+00	1797.00
IUUC-Oga-089053	Otolemur garnettii	81.19	0.00e+00	2445.00
IUUC-Oar-090042	Ovis aries	81.09	0.00e+00	2437.00
IUUC-Ptr-091268	Pan troglodytes	80.15	0.00e+00	2419.00
IUUC-Pan-092376	Papio anubis	80.33	0.00e+00	2421.00
IUUC-Psi-093408	Pelodiscus sinensis	90.12	0.00e+00	2697.00
IUUC-Pfo-096515	Poecilia formosa	67.08	0.00e+00	1725.00
IUUC-Pab-097672	Pongo abelii	78.38	0.00e+00	2389.00
IUUC-Pva-102512	Pteropus vampyrus	86.28	0.00e+00	2021.00
IUUC-Rno-105797	Rattus norvegicus	79.86	0.00e+00	2401.00
IUUC-Sha-107061	Sarcophilus harrisii	74.54	0.00e+00	2241.00
IUUC-Sar-113004	Sorex araneus	67.17	0.00e+00	1198.00
IUUC-Tgu-117254	Taeniopygia guttata	97.76	0.00e+00	2818.00
IUUC-Tru-118186	Takifugu rubripes	66.55	0.00e+00	1748.00
IUUC-Tsy-119003	Tarsius syrichta	77.73	0.00e+00	2241.00
IUUC-Tni-120110	Tetraodon nigroviridis	66.38	0.00e+00	1726.00
IUUC-Ttr-129265	Tursiops truncatus	81.81	0.00e+00	2363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence