iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000419.3	ENSMMUT00000040918.2	ENSMMUP00000033948.2
ENSMMUG00000000419.3	ENSMMUT00000000613.3	ENSMMUP00000000564.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-12	47.6	705	757

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++++G v + + + +q+ gWl+g  +l+gk Gl+Pen+ve
   Q: 705  KAKALYACKAEHDSELSFTAGTVFDNV-HPSQEPGWLEG--TLNGKTGLIPENYVE 757
           679************************.***********..8*************8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MGLPALEFSD CCLDSPHFRE TLKSHEAELD KTNKFIKELI KDGKSLITAL KNLSSAKRKF 60
ADSLNEFKFQ CIGDAETDDE MCIARSLQEF ATVLRNLEDE RIRMIENASE VLITPLEKFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGGGCGGC CCGGGTCCCG GGGGAGGCGC GCCCCCGCGG CTGGGCGCCG CGGGCACTAT 60
GGGGCTCCCA GCTCTCGAGT TCAGCGACTG CTGCCTCGAT AGCCCGCACT TCCGAGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

KEGG

mcc:706084

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	98.56	0.00e+00	1212.00
IUUC-Apl-003321	Anas platyrhynchos	90.47	0.00e+00	1019.00
IUUC-Aca-004570	Anolis carolinensis	90.54	0.00e+00	1279.00
IUUC-Ame-011422	Astyanax mexicanus	78.69	0.00e+00	854.00
IUUC-Bta-013262	Bos taurus	98.61	0.00e+00	1109.00
IUUC-Cel-018542	Caenorhabditis elegans	43.31	3.00e-131	462.00
IUUC-Cja-019208	Callithrix jacchus	99.60	0.00e+00	1320.00
IUUC-Cfa-020928	Canis familiaris	97.76	0.00e+00	1318.00
IUUC-Cpo-021338	Cavia porcellus	98.02	0.00e+00	1221.00
IUUC-Csa-023570	Chlorocebus sabaeus	99.60	0.00e+00	1320.00
IUUC-Dno-029143	Dasypus novemcinctus	98.33	0.00e+00	1215.00
IUUC-Dor-030697	Dipodomys ordii	98.32	0.00e+00	1202.00
IUUC-Dme-032147	Drosophila melanogaster	45.64	2.00e-138	487.00
IUUC-Ete-032645	Echinops telfairi	88.34	0.00e+00	1045.00
IUUC-Eca-033791	Equus caballus	99.04	0.00e+00	1213.00
IUUC-Eeu-035202	Erinaceus europaeus	78.34	4.00e-128	452.00
IUUC-Fca-036131	Felis catus	98.85	0.00e+00	1184.00
IUUC-Fal-037129	Ficedula albicollis	91.58	0.00e+00	1233.00
IUUC-Gga-041023	Gallus gallus	91.58	0.00e+00	1276.00
IUUC-Ggo-044863	Gorilla gorilla	99.39	0.00e+00	1210.00
IUUC-Hsa-046471	Homo sapiens	99.54	0.00e+00	1213.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	98.02	0.00e+00	1234.00
IUUC-Lch-050300	Latimeria chalumnae	80.82	0.00e+00	946.00
IUUC-Loc-052782	Lepisosteus oculatus	80.88	0.00e+00	1052.00
IUUC-Laf-053585	Loxodonta africana	97.76	0.00e+00	1181.00
IUUC-Meu-056107	Macropus eugenii	77.29	0.00e+00	951.00
IUUC-Mga-059914	Meleagris gallopavo	89.22	0.00e+00	1144.00
IUUC-Mmr-060728	Microcebus murinus	98.84	0.00e+00	1100.00
IUUC-Mdo-062387	Monodelphis domestica	92.39	0.00e+00	1212.00
IUUC-Mmu-063756	Mus musculus	97.89	0.00e+00	1218.00
IUUC-Nle-069043	Nomascus leucogenys	95.51	0.00e+00	1002.00
IUUC-Opr-071168	Ochotona princeps	82.31	0.00e+00	993.00
IUUC-Ont-072338	Oreochromis niloticus	77.49	0.00e+00	899.00
IUUC-Oan-073441	Ornithorhynchus anatinus	93.15	0.00e+00	1083.00
IUUC-Ocu-073915	Oryctolagus cuniculus	96.36	0.00e+00	1224.00
IUUC-Ola-086319	Oryzias latipes	76.85	0.00e+00	937.00
IUUC-Oar-089349	Ovis aries	98.40	0.00e+00	1208.00
IUUC-Ptr-091027	Pan troglodytes	99.54	0.00e+00	1214.00
IUUC-Pan-092791	Papio anubis	99.87	0.00e+00	1324.00
IUUC-Psi-093144	Pelodiscus sinensis	91.45	0.00e+00	1318.00
IUUC-Pab-097783	Pongo abelii	99.39	0.00e+00	1214.00
IUUC-Pva-102980	Pteropus vampyrus	98.24	0.00e+00	1246.00
IUUC-Rno-105142	Rattus norvegicus	97.76	0.00e+00	1350.00
IUUC-Sha-107213	Sarcophilus harrisii	92.98	0.00e+00	1220.00
IUUC-Tru-117767	Takifugu rubripes	74.65	0.00e+00	973.00
IUUC-Tsy-119150	Tarsius syrichta	96.05	0.00e+00	1178.00
IUUC-Tni-119893	Tetraodon nigroviridis	73.38	0.00e+00	773.00
IUUC-Ttr-129028	Tursiops truncatus	85.02	0.00e+00	907.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence