iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001606

Ensembl Protein ID

ENSAMEP00000013921.1

UniProt Accession

G1M3K9; G1M3K9_AILME

Genbank Protein ID

ENSAMEP00000013921

Protein Name

Small ubiquitin-related modifier

Genbank Nucleotide ID

ACTA01024341

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000013225.1	ENSAMET00000014500.1	ENSAMEP00000013921.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	3.40e-31	107.9	17	94
ULD/UDP/UBQ/UBQ_Other	6.10e-07	29.3	25	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
           ++++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i++++tp+el++e+ed+ie++++++GG
   Q: 17   EYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGG 94
           69*****************************.**********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++ 
   Q: 25   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQT 92
           445557778899999*************************************************9875 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QEAKPSTEDL GDKKEGEYIK LKVIGQDSSE IHFKVKMTTH LKKLKESYCQ RQGVPMNSLR 60
FLFEGQRIAD NHTPKELGME EEDVIEVYQE QTGGHSTI 98

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGGCAA AACCTTCAAC TGAGGACTTG GGGGATAAGA AGGAAGGAGA ATACATTAAA 60
CTCAAAGTCA TTGGACAGGT GAGTTTCATT GTTTTTCTCC TTTAACTCTC TAAAGTGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0001741--C:XY body
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003638	Anas platyrhynchos	96.94	7.00e-53	197.00
IUUC-Aca-004710	Anolis carolinensis	97.94	2.00e-52	196.00
IUUC-Ago-007749	Ashbya gossypii	47.87	2.00e-18	82.80
IUUC-Ame-011662	Astyanax mexicanus	86.17	3.00e-43	165.00
IUUC-Bta-013491	Bos taurus	98.98	4.00e-54	202.00
IUUC-Cel-018251	Caenorhabditis elegans	65.82	2.00e-28	116.00
IUUC-Cja-019109	Callithrix jacchus	98.98	4.00e-54	201.00
IUUC-Cfa-020657	Canis familiaris	100.00	3.00e-54	202.00
IUUC-Cpo-022508	Cavia porcellus	100.00	1.00e-53	200.00
IUUC-Cre-022970	Chlamydomonas reinhardtii	48.24	1.00e-19	87.00
IUUC-Csa-023026	Chlorocebus sabaeus	97.96	7.00e-44	167.00
IUUC-Cho-024767	Choloepus hoffmanni	98.61	7.00e-39	152.00
IUUC-Dre-028383	Danio rerio	87.10	2.00e-42	162.00
IUUC-Dno-029820	Dasypus novemcinctus	98.98	4.00e-54	202.00
IUUC-Ete-032782	Echinops telfairi	74.23	9.00e-35	137.00
IUUC-Eca-033958	Equus caballus	100.00	3.00e-54	202.00
IUUC-Eeu-034822	Erinaceus europaeus	100.00	3.00e-53	199.00
IUUC-Fca-035601	Felis catus	100.00	3.00e-54	202.00
IUUC-Fal-036740	Ficedula albicollis	96.94	1.00e-52	198.00
IUUC-Gmo-038847	Gadus morhua	91.18	3.00e-33	132.00
IUUC-Gga-040129	Gallus gallus	96.94	4.00e-53	198.00
IUUC-Gac-042112	Gasterosteus aculeatus	88.17	5.00e-45	171.00
IUUC-Ggo-045413	Gorilla gorilla	98.98	4.00e-54	202.00
IUUC-Hsa-046108	Homo sapiens	98.98	4.00e-54	202.00
IUUC-Itr-047968	Ictidomys tridecemlineatus	100.00	9.00e-54	200.00
IUUC-Lch-049881	Latimeria chalumnae	84.04	2.00e-37	146.00
IUUC-Loc-052189	Lepisosteus oculatus	91.49	6.00e-48	181.00
IUUC-Laf-053478	Loxodonta africana	97.96	2.00e-53	199.00
IUUC-Mcc-055059	Macaca mulatta	64.86	6.00e-47	179.00
IUUC-Meu-056112	Macropus eugenii	95.92	2.00e-52	197.00
IUUC-Mga-060035	Meleagris gallopavo	96.94	5.00e-53	198.00
IUUC-Mmr-060903	Microcebus murinus	98.98	4.00e-54	202.00
IUUC-Mdo-062633	Monodelphis domestica	95.92	1.00e-52	197.00
IUUC-Mmu-063272	Mus musculus	98.98	4.00e-54	202.00
IUUC-Mpu-066505	Mustela putorius furo	98.98	2.00e-53	200.00
IUUC-Mlu-067469	Myotis lucifugus	98.98	5.00e-54	201.00
IUUC-Nle-069344	Nomascus leucogenys	98.63	9.00e-40	154.00
IUUC-Opr-070351	Ochotona princeps	48.98	2.00e-16	77.80
IUUC-Ont-071436	Oreochromis niloticus	88.17	5.00e-45	171.00
IUUC-Oan-072986	Ornithorhynchus anatinus	98.08	3.00e-25	105.00
IUUC-Ocu-073781	Oryctolagus cuniculus	95.92	6.00e-52	194.00
IUUC-Ola-086373	Oryzias latipes	87.10	2.00e-43	166.00
IUUC-Olu-087670	Ostreococcus lucimarinus	44.29	1.00e-16	77.00
IUUC-Oga-088024	Otolemur garnettii	88.78	2.00e-48	183.00
IUUC-Oar-089991	Ovis aries	98.98	5.00e-54	201.00
IUUC-Ptr-090688	Pan troglodytes	96.94	6.00e-53	198.00
IUUC-Pan-092204	Papio anubis	98.98	4.00e-54	202.00
IUUC-Psi-093396	Pelodiscus sinensis	96.94	6.00e-53	198.00
IUUC-Pfo-096306	Poecilia formosa	86.46	3.00e-44	170.00
IUUC-Pab-098393	Pongo abelii	98.98	4.00e-54	204.00
IUUC-Pca-100237	Procavia capensis	97.96	6.00e-52	195.00
IUUC-Pva-102353	Pteropus vampyrus	100.00	2.00e-41	160.00
IUUC-Pgr-103683	Puccinia graminis	40.74	4.00e-15	72.80
IUUC-Rno-105286	Rattus norvegicus	98.98	4.00e-54	202.00
IUUC-Sce-106231	Saccharomyces cerevisiae	47.92	5.00e-19	85.50
IUUC-Sha-106712	Sarcophilus harrisii	97.22	1.00e-38	150.00
IUUC-Sja-107710	Schizosaccharomyces japonicus	50.00	4.00e-22	96.30
IUUC-Spo-108261	Schizosaccharomyces pombe	52.13	5.00e-22	95.90
IUUC-Sit-110664	Setaria italica	30.86	8.00e-08	49.30
IUUC-Sar-113550	Sorex araneus	97.94	8.00e-53	197.00
IUUC-Sre-115172	Sporisorium reilianum	53.16	7.00e-20	87.80
IUUC-Ssc-115837	Sus scrofa	94.90	1.00e-52	197.00
IUUC-Tgu-117064	Taeniopygia guttata	96.91	2.00e-52	196.00
IUUC-Tru-117752	Takifugu rubripes	88.17	3.00e-45	172.00
IUUC-Tsy-119358	Tarsius syrichta	100.00	2.00e-40	156.00
IUUC-Tni-120621	Tetraodon nigroviridis	88.17	1.00e-44	170.00
IUUC-Tme-126902	Tuber melanosporum	45.12	7.00e-18	81.30
IUUC-Tbe-127355	Tupaia belangeri	74.23	9.00e-35	137.00
IUUC-Ttr-128166	Tursiops truncatus	98.98	3.00e-53	199.00
IUUC-Uma-129444	Ustilago maydis	53.16	2.00e-20	89.70
IUUC-Vpa-130172	Vicugna pacos	98.98	5.00e-54	202.00
IUUC-Xtr-132473	Xenopus tropicalis	93.94	4.00e-50	188.00
IUUC-Xma-133814	Xiphophorus maculatus	86.46	5.00e-45	171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence