iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088024

Ensembl Protein ID

ENSOGAP00000021888.1

UniProt Accession

H0Y0J5; H0Y0J5_OTOGA

Genbank Protein ID

ENSOGAP00000021888

Protein Name

Small ubiquitin-related modifier

Genbank Nucleotide ID

AAQR03045675

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000024501.1	ENSOGAT00000033239.1	ENSOGAP00000021888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	9.50e-29	100.0	20	96
ULD/UDP/UBQ/UBQ_Other	9.70e-06	25.4	29	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksG 84
           ++++lkv gqd+ e+++k+k++++lkkl+e+ +++r+++ +ns+rf+f+gq+i++++tp+el++e+ed+ie++++++G
   Q: 20   EYIKLKVTGQDSTEIHLKVKMTTHLKKLKES-HCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTG 96
           79*****************************.*********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 10   gseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekk 73
             +++++  v+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++
   Q: 29   QDSTEIHlkVKMTTHLKKLKESHCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQ 94
           2244444449999999*****9999**************************************986 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSDQEAKPST EDLGDRMEGE YIKLKVTGQD STEIHLKVKM TTHLKKLKES HCQRQGVPMN 60
SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGSFNS L 101

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGTGGTG CTGTGCTATG GGAAAGGAAG ACGAATTTGT AAACCCCAGA GTGAGGTTCT 60
GCCTACCCCA GGCTGCTGCT GCGTGAAGAC CCCTGAAGGG AAGCCACCAT CACCATGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0001741--C:XY body
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001606	Ailuropoda melanoleuca	88.78	1.00e-48	183.00
IUUC-Apl-003638	Anas platyrhynchos	86.73	3.00e-47	179.00
IUUC-Aca-004710	Anolis carolinensis	87.13	9.00e-49	184.00
IUUC-Ame-011662	Astyanax mexicanus	78.57	2.00e-41	159.00
IUUC-Bta-013491	Bos taurus	89.11	3.00e-50	189.00
IUUC-Cel-018251	Caenorhabditis elegans	62.50	4.00e-27	112.00
IUUC-Cja-019109	Callithrix jacchus	86.14	1.00e-48	183.00
IUUC-Cfa-020657	Canis familiaris	89.11	2.00e-50	189.00
IUUC-Cpo-022508	Cavia porcellus	89.69	3.00e-48	182.00
IUUC-Cre-022970	Chlamydomonas reinhardtii	43.75	2.00e-18	82.80
IUUC-Csa-023026	Chlorocebus sabaeus	88.12	6.00e-40	154.00
IUUC-Cho-024767	Choloepus hoffmanni	88.89	1.00e-34	137.00
IUUC-Cne-027072	Cryptococcus neoformans	43.94	2.00e-12	63.90
IUUC-Dre-028383	Danio rerio	80.21	2.00e-40	156.00
IUUC-Dno-029820	Dasypus novemcinctus	89.11	3.00e-50	189.00
IUUC-Ete-032782	Echinops telfairi	63.92	4.00e-29	119.00
IUUC-Eca-033958	Equus caballus	89.11	2.00e-50	189.00
IUUC-Eeu-034822	Erinaceus europaeus	93.75	5.00e-50	188.00
IUUC-Fca-035601	Felis catus	88.78	2.00e-48	183.00
IUUC-Fal-036740	Ficedula albicollis	86.73	4.00e-47	179.00
IUUC-Gmo-038847	Gadus morhua	84.06	6.00e-31	124.00
IUUC-Gga-040129	Gallus gallus	87.13	3.00e-49	185.00
IUUC-Gac-042112	Gasterosteus aculeatus	79.59	4.00e-43	165.00
IUUC-Ggo-045413	Gorilla gorilla	89.11	3.00e-50	189.00
IUUC-Hsa-046108	Homo sapiens	89.11	3.00e-50	189.00
IUUC-Itr-047968	Ictidomys tridecemlineatus	90.00	4.00e-50	188.00
IUUC-Lch-049881	Latimeria chalumnae	78.12	2.00e-35	140.00
IUUC-Loc-052189	Lepisosteus oculatus	83.16	2.00e-44	169.00
IUUC-Laf-053478	Loxodonta africana	88.78	2.00e-48	183.00
IUUC-Mcc-055059	Macaca mulatta	75.49	3.00e-42	164.00
IUUC-Meu-056112	Macropus eugenii	87.13	2.00e-49	187.00
IUUC-Mga-060035	Meleagris gallopavo	86.73	2.00e-47	179.00
IUUC-Mmr-060903	Microcebus murinus	89.11	3.00e-50	189.00
IUUC-Mdo-062633	Monodelphis domestica	87.13	2.00e-49	186.00
IUUC-Mmu-063272	Mus musculus	89.11	3.00e-50	189.00
IUUC-Mpu-066505	Mustela putorius furo	87.76	9.00e-48	181.00
IUUC-Mlu-067991	Myotis lucifugus	91.67	2.00e-44	169.00
IUUC-Nle-069344	Nomascus leucogenys	85.53	2.00e-35	139.00
IUUC-Opr-070351	Ochotona princeps	42.57	5.00e-14	70.10
IUUC-Ont-071436	Oreochromis niloticus	79.59	4.00e-43	165.00
IUUC-Oan-072986	Ornithorhynchus anatinus	85.19	7.00e-23	97.80
IUUC-Ocu-074220	Oryctolagus cuniculus	93.07	1.00e-52	197.00
IUUC-Ola-086373	Oryzias latipes	78.57	1.00e-41	160.00
IUUC-Olu-087670	Ostreococcus lucimarinus	40.00	2.00e-14	70.10
IUUC-Oar-089991	Ovis aries	87.13	1.00e-48	183.00
IUUC-Ptr-090688	Pan troglodytes	89.11	3.00e-50	189.00
IUUC-Pan-092204	Papio anubis	89.11	3.00e-50	189.00
IUUC-Psi-093396	Pelodiscus sinensis	86.73	3.00e-47	179.00
IUUC-Pfo-096306	Poecilia formosa	79.59	2.00e-42	163.00
IUUC-Pab-098393	Pongo abelii	89.11	4.00e-50	190.00
IUUC-Pca-100237	Procavia capensis	88.12	4.00e-48	183.00
IUUC-Pva-102353	Pteropus vampyrus	92.41	4.00e-40	155.00
IUUC-Rno-105286	Rattus norvegicus	89.11	3.00e-50	189.00
IUUC-Sce-106231	Saccharomyces cerevisiae	44.68	3.00e-16	76.30
IUUC-Sha-106712	Sarcophilus harrisii	88.89	6.00e-35	137.00
IUUC-Sar-113550	Sorex araneus	88.66	1.00e-47	180.00
IUUC-Sre-115172	Sporisorium reilianum	49.37	6.00e-18	81.60
IUUC-Ssc-115837	Sus scrofa	86.14	4.00e-49	185.00
IUUC-Tgu-117064	Taeniopygia guttata	86.60	7.00e-47	177.00
IUUC-Tru-117752	Takifugu rubripes	79.59	3.00e-43	166.00
IUUC-Tsy-119358	Tarsius syrichta	92.00	2.00e-37	146.00
IUUC-Tni-120621	Tetraodon nigroviridis	79.59	1.00e-42	164.00
IUUC-Tbe-127355	Tupaia belangeri	63.92	4.00e-29	119.00
IUUC-Ttr-128166	Tursiops truncatus	89.11	5.00e-50	189.00
IUUC-Uma-129444	Ustilago maydis	49.37	1.00e-18	84.00
IUUC-Vpa-130172	Vicugna pacos	89.11	4.00e-50	189.00
IUUC-Xtr-132473	Xenopus tropicalis	83.33	3.00e-46	176.00
IUUC-Xma-133814	Xiphophorus maculatus	79.59	4.00e-43	165.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence