iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011855

Ensembl Protein ID

ENSAMXP00000004997.1

UniProt Accession

W5KBN6; W5KBN6_ASTMX

Genbank Protein ID

ENSAMXP00000004997

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

APWO01018660

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000004868.1	ENSAMXT00000004997.1	ENSAMXP00000004997.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-66	225.4	177	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +     + +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 177  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ----ANSCLVCEMSQLFQEFYSGHRSPHIPFRLLHLVWTHARHLAGYEQQ 260
           9*****************************.99999876....579******************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k       ++         ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 261  DAHEFLIAALDVLHRHCKV------HQ-------GDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 336
           *****************22......11.......223346677889999**************************************** PP
   S: 180  eetkke...................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
           ++   +                   +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++k+lP v ++hLkRf  +++ k r+ki
   Q: 337  STPFWPlspgsdgnvngeshptgatTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKRLPIVACFHLKRF--EHSAKLRRKI 423
           *87777***********************************************************************..5666899*** PP
   S: 250  nkkvefpleLdlspfct 266
           +++v+fpleLd++pf++
   Q: 424  TTYVSFPLELDMTPFMA 440
           **************997 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

VMSPAGCSHV NGFKVDNWKQ NLRVIYQCFV WSGSAETRKR KAKSCMCHMC GAHLNRLHSC 60
LHCVFFGCFT KKHIHEHAKT KRHNLGMTSV YTQLYCRLYE TFYIYSVLII QCCKNTVFLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATGAGTC CAGCCGGCTG CTCCCATGTG AATGGCTTCA AAGTGGATAA CTGGAAGCAG 60
AACCTGCGAG TCATCTACCA GTGCTTTGTG TGGAGTGGCT CGGCTGAAAC CAGGAAACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-033175	Echinops telfairi	62.53	3.00e-150	525.00
IUUC-Obr-076652	Oryza brachyantha	42.76	1.00e-60	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence