iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004048

Ensembl Protein ID

ENSAPLP00000008356.1

UniProt Accession

R0KKU3; R0KKU3_ANAPL

Genbank Protein ID

EOA93783.1

Protein Name

BRCA1-associated protein

Genbank Nucleotide ID

ADON01141378

Gene Name

BRAP; Anapl_12891

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008647.1	ENSAPLT00000009033.1	ENSAPLP00000008356.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-07	31.0	185	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cle++++     l++ C+H fh +Clq+w           +CP+Cr
   Q: 185  CTVCLERMDESvngILTTLCNHSFHSQCLQRW--------EDTTCPVCR 225
           9*******77333366777*************........7778****8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

KDEPKGAVEG RKSSEAASAE DKTNPDEQSK EREAAPDSPS KQLPDQISFF SGNPSVEIVH 60
GIMHLYKTNK MTSLKEDVRR SAMLCILTVP ATMTSHDLMK FVASFYDVIE HMKIIRDSTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGATGAAC CAAAAGGTGC CGTGGAAGGA AGGAAATCTT CGGAGGCTGC ATCTGCTGAG 60
GACAAAACCA ACCCCGATGA GCAGAGCAAA GAGCGTGAGG CTGCTCCGGA CTCGCCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011422--BRAP2
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50089--ZF_RING_2
PS50271--ZF_UBP

Pfam

PF07576--BRAP2
PF13639--zf-RING_2
PF02148--zf-UBP

SMART

SM00184--RING
SM00290--ZnF_UBP

Gene Ontology

GO:0005829--C:cytosol
GO:0031965--C:nuclear membrane
GO:0000151--C:ubiquitin ligase complex
GO:0008139--F:nuclear localization sequence binding
GO:0003676--F:nucleic acid binding
GO:0000166--F:nucleotide binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0000165--P:MAPK cascade
GO:0009968--P:negative regulation of signal transduction
GO:0007265--P:Ras protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000519	Aegilops tauschii	29.35	3.00e-52	199.00
IUUC-Aml-002229	Ailuropoda melanoleuca	95.14	0.00e+00	910.00
IUUC-Atr-002785	Amborella trichopoda	39.20	3.00e-93	335.00
IUUC-Aca-005133	Anolis carolinensis	89.04	0.00e+00	904.00
IUUC-Aly-006306	Arabidopsis lyrata	35.85	5.00e-79	288.00
IUUC-Ath-007604	Arabidopsis thaliana	35.84	9.00e-82	296.00
IUUC-Ago-007905	Ashbya gossypii	35.44	1.00e-70	260.00
IUUC-Acl-008310	Aspergillus clavatus	32.35	3.00e-68	252.00
IUUC-Afl-008497	Aspergillus flavus	32.14	2.00e-62	233.00
IUUC-Afu-008830	Aspergillus fumigatus	32.15	1.00e-66	247.00
IUUC-Ani-009485	Aspergillus nidulans	32.44	3.00e-69	255.00
IUUC-Ang-009603	Aspergillus niger	36.83	1.00e-65	243.00
IUUC-Aor-009935	Aspergillus oryzae	32.57	8.00e-67	247.00
IUUC-Ate-010485	Aspergillus terreus	32.05	1.00e-70	259.00
IUUC-Ame-011516	Astyanax mexicanus	85.17	0.00e+00	743.00
IUUC-Bgr-011985	Blumeria graminis	27.66	2.00e-47	183.00
IUUC-Bta-013203	Bos taurus	91.75	0.00e+00	928.00
IUUC-Bci-013788	Botrytis cinerea	34.64	1.00e-55	211.00
IUUC-Bdi-014763	Brachypodium distachyon	35.16	2.00e-83	302.00
IUUC-Bol-015518	Brassica oleracea	34.27	7.00e-80	291.00
IUUC-Bra-017435	Brassica rapa	33.80	2.00e-80	292.00
IUUC-Cel-018194	Caenorhabditis elegans	41.12	7.00e-107	380.00
IUUC-Cja-018948	Callithrix jacchus	90.36	0.00e+00	881.00
IUUC-Cfa-020377	Canis familiaris	88.67	0.00e+00	929.00
IUUC-Cpo-021930	Cavia porcellus	90.29	0.00e+00	882.00
IUUC-Cre-022571	Chlamydomonas reinhardtii	42.35	3.00e-58	218.00
IUUC-Csa-023554	Chlorocebus sabaeus	91.35	0.00e+00	753.00
IUUC-Cho-025045	Choloepus hoffmanni	83.53	2.00e-79	290.00
IUUC-Cin-025326	Ciona intestinalis	45.34	7.00e-114	403.00
IUUC-Csv-026232	Ciona savignyi	44.20	9.00e-115	406.00
IUUC-Cgl-026587	Colletotrichum gloeosporioides	30.75	3.00e-62	232.00
IUUC-Cne-026980	Cryptococcus neoformans	30.48	5.00e-50	192.00
IUUC-Cme-027262	Cyanidioschyzon merolae	31.59	1.00e-59	223.00
IUUC-Dre-028521	Danio rerio	82.00	0.00e+00	827.00
IUUC-Dno-029291	Dasypus novemcinctus	92.10	0.00e+00	907.00
IUUC-Dor-030231	Dipodomys ordii	79.53	0.00e+00	803.00
IUUC-Dse-031234	Dothistroma septosporum	33.55	2.00e-56	213.00
IUUC-Dme-032095	Drosophila melanogaster	46.87	2.00e-121	428.00
IUUC-Ete-032227	Echinops telfairi	80.83	7.00e-131	460.00
IUUC-Eca-034404	Equus caballus	91.34	0.00e+00	924.00
IUUC-Eeu-035030	Erinaceus europaeus	87.67	1.00e-109	390.00
IUUC-Fca-035428	Felis catus	91.13	0.00e+00	922.00
IUUC-Fal-037435	Ficedula albicollis	97.11	0.00e+00	957.00
IUUC-Fox-037733	Fusarium oxysporum	32.43	3.00e-64	239.00
IUUC-Fso-038427	Fusarium solani	31.74	1.00e-62	234.00
IUUC-Gmo-038817	Gadus morhua	82.23	0.00e+00	785.00
IUUC-Ggr-039949	Gaeumannomyces graminis	28.77	5.00e-59	222.00
IUUC-Gga-040929	Gallus gallus	97.73	0.00e+00	984.00
IUUC-Gac-041893	Gasterosteus aculeatus	84.82	0.00e+00	811.00
IUUC-Gma-043119	Glycine max	36.81	4.00e-84	305.00
IUUC-Ggo-045106	Gorilla gorilla	91.39	0.00e+00	695.00
IUUC-Hsa-045685	Homo sapiens	88.89	0.00e+00	927.00
IUUC-Hvu-047475	Hordeum vulgare	33.21	1.00e-34	139.00
IUUC-Itr-048406	Ictidomys tridecemlineatus	90.93	0.00e+00	891.00
IUUC-Kpa-049175	Komagataella pastoris	37.41	6.00e-67	248.00
IUUC-Lch-050408	Latimeria chalumnae	89.58	0.00e+00	880.00
IUUC-Lpe-050777	Leersia perrieri	33.82	2.00e-67	249.00
IUUC-Loc-052160	Lepisosteus oculatus	68.18	0.00e+00	627.00
IUUC-Lma-053095	Leptosphaeria maculans	34.24	3.00e-78	285.00
IUUC-Laf-053497	Loxodonta africana	88.74	0.00e+00	920.00
IUUC-Mcc-055381	Macaca mulatta	91.34	0.00e+00	924.00
IUUC-Meu-056402	Macropus eugenii	70.69	0.00e+00	643.00
IUUC-Mor-057002	Magnaporthe oryzae	30.31	5.00e-63	235.00
IUUC-Mpo-057508	Magnaporthe poae	26.52	1.00e-56	214.00
IUUC-Mtr-058619	Medicago truncatula	35.40	1.00e-68	253.00
IUUC-Mla-058901	Melampsora laricipopulina	34.66	8.00e-73	268.00
IUUC-Mga-059667	Meleagris gallopavo	99.13	0.00e+00	961.00
IUUC-Mvi-060229	Microbotryum violaceum	28.88	3.00e-64	239.00
IUUC-Mmr-060881	Microcebus murinus	94.48	0.00e+00	803.00
IUUC-Mdo-062573	Monodelphis domestica	93.83	0.00e+00	870.00
IUUC-Mmu-063656	Mus musculus	87.89	0.00e+00	902.00
IUUC-Mac-065512	Musa acuminata	37.15	7.00e-82	297.00
IUUC-Mpu-065816	Mustela putorius furo	91.34	0.00e+00	924.00
IUUC-Mlu-067225	Myotis lucifugus	89.44	0.00e+00	920.00
IUUC-Nfi-068534	Neosartorya fischeri	32.15	2.00e-67	250.00
IUUC-Ncr-068801	Neurospora crassa	27.81	3.00e-61	229.00
IUUC-Nle-069258	Nomascus leucogenys	90.72	0.00e+00	838.00
IUUC-Opr-070877	Ochotona princeps	86.54	0.00e+00	868.00
IUUC-Ont-072141	Oreochromis niloticus	81.19	0.00e+00	808.00
IUUC-Oan-072961	Ornithorhynchus anatinus	90.27	0.00e+00	922.00
IUUC-Ocu-074020	Oryctolagus cuniculus	92.09	0.00e+00	773.00
IUUC-Oba-075084	Oryza barthii	31.39	4.00e-68	251.00
IUUC-Obr-076840	Oryza brachyantha	36.28	2.00e-80	292.00
IUUC-Ogl-077880	Oryza glaberrima	42.66	3.00e-79	288.00
IUUC-Ogu-078968	Oryza glumaepatula	31.39	2.00e-68	253.00
IUUC-Oin-079200	Oryza indica	42.66	2.00e-79	289.00
IUUC-Olo-080753	Oryza longistaminata	33.50	5.00e-62	231.00
IUUC-Ome-081756	Oryza meridionalis	31.22	4.00e-68	251.00
IUUC-Oni-082434	Oryza nivara	31.39	2.00e-68	252.00
IUUC-Opu-083262	Oryza punctata	31.02	1.00e-67	250.00
IUUC-Oru-084381	Oryza rufipogon	31.39	2.00e-68	253.00
IUUC-Osa-085760	Oryza sativa	46.62	1.00e-71	262.00
IUUC-Ola-087390	Oryzias latipes	80.43	0.00e+00	757.00
IUUC-Olu-087694	Ostreococcus lucimarinus	32.07	9.00e-60	224.00
IUUC-Oga-088612	Otolemur garnettii	91.96	0.00e+00	898.00
IUUC-Oar-089988	Ovis aries	90.93	0.00e+00	922.00
IUUC-Ptr-090637	Pan troglodytes	89.08	0.00e+00	929.00
IUUC-Pan-092506	Papio anubis	91.34	0.00e+00	922.00
IUUC-Psi-093026	Pelodiscus sinensis	93.21	0.00e+00	896.00
IUUC-Pno-094779	Phaeosphaeria nodorum	32.00	6.00e-58	218.00
IUUC-Ppa-095731	Physcomitrella patens	40.67	1.00e-95	343.00
IUUC-Pfo-096725	Poecilia formosa	82.85	0.00e+00	785.00
IUUC-Pab-098413	Pongo abelii	90.21	0.00e+00	723.00
IUUC-Pop-099538	Populus trichocarpa	38.69	6.00e-84	304.00
IUUC-Pca-100130	Procavia capensis	78.51	0.00e+00	774.00
IUUC-Ppe-101843	Prunus persica	38.46	2.00e-87	315.00
IUUC-Pva-102752	Pteropus vampyrus	89.45	0.00e+00	933.00
IUUC-Pgr-103478	Puccinia graminis	38.48	3.00e-76	279.00
IUUC-Ptt-103921	Puccinia triticina	38.16	8.00e-71	261.00
IUUC-Pte-104032	Pyrenophora teres	34.18	2.00e-75	276.00
IUUC-Pyt-104480	Pyrenophora triticirepentis	32.03	6.00e-73	268.00
IUUC-Rno-106037	Rattus norvegicus	76.47	0.00e+00	726.00
IUUC-Sce-106310	Saccharomyces cerevisiae	32.54	6.00e-61	228.00
IUUC-Sha-106752	Sarcophilus harrisii	89.65	0.00e+00	903.00
IUUC-Sja-107665	Schizosaccharomyces japonicus	38.50	3.00e-83	301.00
IUUC-Spo-108042	Schizosaccharomyces pombe	34.38	2.00e-73	269.00
IUUC-Ssl-108504	Sclerotinia sclerotiorum	30.47	5.00e-56	212.00
IUUC-Smo-109399	Selaginella moellendorffii	39.25	3.00e-92	331.00
IUUC-Sit-110251	Setaria italica	38.48	1.00e-88	319.00
IUUC-Sly-111563	Solanum lycopersicum	38.46	8.00e-78	283.00
IUUC-Stu-112294	Solanum tuberosum	38.83	4.00e-81	295.00
IUUC-Sar-113080	Sorex araneus	75.48	6.00e-138	483.00
IUUC-Sbi-113915	Sorghum bicolor	38.51	1.00e-85	310.00
IUUC-Sre-114897	Sporisorium reilianum	35.86	9.00e-59	221.00
IUUC-Ssc-115369	Sus scrofa	97.83	5.00e-111	392.00
IUUC-Tgu-116710	Taeniopygia guttata	97.52	0.00e+00	985.00
IUUC-Tru-117941	Takifugu rubripes	83.60	0.00e+00	784.00
IUUC-Tsy-118902	Tarsius syrichta	78.80	9.00e-101	360.00
IUUC-Tni-120587	Tetraodon nigroviridis	80.63	0.00e+00	810.00
IUUC-Tca-121425	Theobroma cacao	38.83	4.00e-90	325.00
IUUC-Tre-121874	Trichoderma reesei	31.13	3.00e-64	239.00
IUUC-Tvi-122266	Trichoderma virens	33.87	3.00e-63	236.00
IUUC-Tae-124194	Triticum aestivum	35.68	1.00e-80	293.00
IUUC-Tur-126467	Triticum urartu	33.10	2.00e-53	202.00
IUUC-Tme-127096	Tuber melanosporum	36.36	2.00e-59	223.00
IUUC-Tbe-128012	Tupaia belangeri	85.06	0.00e+00	843.00
IUUC-Ttr-128388	Tursiops truncatus	91.75	0.00e+00	928.00
IUUC-Uma-129610	Ustilago maydis	33.63	2.00e-56	213.00
IUUC-Vda-129830	Verticillium dahliae	28.87	4.00e-58	219.00
IUUC-Vpa-130171	Vicugna pacos	90.06	0.00e+00	933.00
IUUC-Vvi-131063	Vitis vinifera	42.86	2.00e-82	299.00
IUUC-Xtr-132313	Xenopus tropicalis	87.43	0.00e+00	902.00
IUUC-Xma-133303	Xiphophorus maculatus	82.44	0.00e+00	786.00
IUUC-Yli-134669	Yarrowia lipolytica	32.67	5.00e-66	244.00
IUUC-Zma-135783	Zea mays	37.39	3.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence