iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017602.3	ENSMMUT00000024754.3	ENSMMUP00000023167.3
ENSMMUG00000017602.3	ENSMMUT00000071105.1	ENSMMUP00000057234.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.80e-22	78.4	1001	1072

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            ++efl+pI+ +lM+dPvvlp s++t+drs+I+++l s+++ +P++r+plt +++ Pn++l++ iq+w++e++
   Q: 1001 ACDEFLDPIMSTLMCDPVVLPsSRVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 1072
           579******************9******************9.***************************9976 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MTDQENNNNI SSNPFAALFG SLADAKQFAA IQKEQLKQQS GKGVTFNSIH FLADELPASP 60
DDSDNSVSES LDEFDYSVAE ISRSFRSQQE ICEQLNINHM IQRIFLITLD NSDPSLKSGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGACC AGGAGAATAA CAACAACATC TCAAGTAACC CCTTTGCTGC TCTTTTTGGC 60
TCCCTGGCTG ATGCCAAACA GTTTGCGGCA ATCCAAAAAG AGCAGCTGAA GCAACAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001281	Ailuropoda melanoleuca	96.96	0.00e+00	2078.00
IUUC-Apl-003514	Anas platyrhynchos	89.50	0.00e+00	1900.00
IUUC-Aca-005167	Anolis carolinensis	85.16	0.00e+00	1759.00
IUUC-Ame-010905	Astyanax mexicanus	66.67	0.00e+00	707.00
IUUC-Bta-012413	Bos taurus	95.83	0.00e+00	2080.00
IUUC-Cja-019715	Callithrix jacchus	97.70	0.00e+00	2125.00
IUUC-Cfa-021185	Canis familiaris	97.59	0.00e+00	2143.00
IUUC-Cpo-021516	Cavia porcellus	97.41	0.00e+00	2110.00
IUUC-Csa-023765	Chlorocebus sabaeus	98.61	0.00e+00	2108.00
IUUC-Cho-024614	Choloepus hoffmanni	98.64	0.00e+00	868.00
IUUC-Cin-025532	Ciona intestinalis	36.91	2.00e-164	573.00
IUUC-Csv-025834	Ciona savignyi	52.26	2.00e-48	184.00
IUUC-Dre-028223	Danio rerio	76.31	0.00e+00	1607.00
IUUC-Dno-029785	Dasypus novemcinctus	96.39	0.00e+00	2092.00
IUUC-Dor-030421	Dipodomys ordii	93.01	0.00e+00	1971.00
IUUC-Dme-031715	Drosophila melanogaster	35.46	7.00e-134	471.00
IUUC-Ete-032767	Echinops telfairi	95.16	0.00e+00	1321.00
IUUC-Eca-033587	Equus caballus	97.31	0.00e+00	2107.00
IUUC-Fca-035622	Felis catus	96.78	0.00e+00	2131.00
IUUC-Fal-037262	Ficedula albicollis	86.97	0.00e+00	1897.00
IUUC-Gmo-038686	Gadus morhua	72.11	0.00e+00	1571.00
IUUC-Gga-041222	Gallus gallus	87.43	0.00e+00	1943.00
IUUC-Gac-042637	Gasterosteus aculeatus	73.22	0.00e+00	1562.00
IUUC-Ggo-044685	Gorilla gorilla	97.97	0.00e+00	2130.00
IUUC-Hsa-046176	Homo sapiens	98.52	0.00e+00	2134.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	98.89	0.00e+00	1065.00
IUUC-Lch-049630	Latimeria chalumnae	80.47	0.00e+00	1745.00
IUUC-Loc-052727	Lepisosteus oculatus	76.08	0.00e+00	1645.00
IUUC-Laf-054041	Loxodonta africana	96.50	0.00e+00	2124.00
IUUC-Meu-055991	Macropus eugenii	88.42	0.00e+00	1938.00
IUUC-Mga-059596	Meleagris gallopavo	88.38	0.00e+00	1782.00
IUUC-Mmr-061244	Microcebus murinus	96.02	0.00e+00	1741.00
IUUC-Mdo-062335	Monodelphis domestica	88.81	0.00e+00	1919.00
IUUC-Mmu-063572	Mus musculus	96.22	0.00e+00	2102.00
IUUC-Mpu-066444	Mustela putorius furo	92.89	0.00e+00	2023.00
IUUC-Mlu-068232	Myotis lucifugus	95.37	0.00e+00	2081.00
IUUC-Nle-070036	Nomascus leucogenys	97.88	0.00e+00	2127.00
IUUC-Opr-070503	Ochotona princeps	90.79	0.00e+00	1364.00
IUUC-Ont-072389	Oreochromis niloticus	75.09	0.00e+00	1601.00
IUUC-Oan-073114	Ornithorhynchus anatinus	88.39	0.00e+00	1721.00
IUUC-Ocu-074370	Oryctolagus cuniculus	97.68	0.00e+00	1843.00
IUUC-Ola-086562	Oryzias latipes	73.54	0.00e+00	1586.00
IUUC-Oga-088146	Otolemur garnettii	96.19	0.00e+00	2076.00
IUUC-Oar-089190	Ovis aries	95.83	0.00e+00	2054.00
IUUC-Ptr-090592	Pan troglodytes	97.70	0.00e+00	2124.00
IUUC-Pan-092271	Papio anubis	98.80	0.00e+00	2138.00
IUUC-Psi-093730	Pelodiscus sinensis	86.59	0.00e+00	1912.00
IUUC-Pma-094120	Petromyzon marinus	77.05	4.00e-132	464.00
IUUC-Pfo-097077	Poecilia formosa	72.55	0.00e+00	1557.00
IUUC-Pab-098069	Pongo abelii	97.61	0.00e+00	2090.00
IUUC-Pca-100762	Procavia capensis	92.18	0.00e+00	1947.00
IUUC-Pva-103149	Pteropus vampyrus	96.22	0.00e+00	2092.00
IUUC-Rno-105342	Rattus norvegicus	96.04	0.00e+00	2098.00
IUUC-Sha-106555	Sarcophilus harrisii	89.45	0.00e+00	1960.00
IUUC-Sly-110848	Solanum lycopersicum	38.98	2.00e-76	280.00
IUUC-Sar-113131	Sorex araneus	91.10	0.00e+00	1193.00
IUUC-Ssc-115841	Sus scrofa	96.57	0.00e+00	2090.00
IUUC-Tgu-116823	Taeniopygia guttata	85.37	0.00e+00	1867.00
IUUC-Tru-118249	Takifugu rubripes	74.17	0.00e+00	1576.00
IUUC-Tsy-119112	Tarsius syrichta	99.74	0.00e+00	753.00
IUUC-Tni-119848	Tetraodon nigroviridis	72.74	0.00e+00	1540.00
IUUC-Tbe-127889	Tupaia belangeri	82.10	0.00e+00	859.00
IUUC-Ttr-129300	Tursiops truncatus	86.79	0.00e+00	1166.00
IUUC-Vpa-130215	Vicugna pacos	95.68	0.00e+00	2066.00
IUUC-Xtr-132107	Xenopus tropicalis	79.83	0.00e+00	1697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence