iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018503.3	ENSMMUT00000026018.3	ENSMMUP00000024346.3
ENSMMUG00000018503.3	ENSMMUT00000064771.1	ENSMMUP00000054167.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-25	87.9	839	873
UBD/Beta-Prp	9.60e-55	187.0	801	1012

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c++ f  +tl +s+s D t+++W+l tg
   Q: 839  GHTGEVRCVKvFaKGTLAISASKDYTLRLWNLLTG 873
           8********9778669***************9887 PP

UBD/Beta-Prp

   S: 54   evtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.....tlsg 135
           ++ta+ +  ++k+lv g +D++i vwd++    +h l+gh+ +v++++++++g   +s+s+d t+r+w+l tgq+  +      +++
   Q: 801  GITAMAWGVEEKLLVIGTQDGIITVWDMEEQHVIHMLTGHTGEVRCVKVFAKGTLAISASKDYTLRLWNLLTGQEKFAiwdggSKNP 887
           688999999999**************************************************************9999999999999 PP
   S: 136  hdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           ++  +++++v++  +++ s+s+ ++++ W+l+t++l+ +  g+  d+  ++++  ++  l+++s+dg v lw+  tg+   +++  +
   Q: 888  TEPQIWSLHVDEAYKVVYSASA-SKINAWNLETAELVFHILGDASDPWMCMAMLASQATLLTVSRDGVVSLWSSATGKLQGQQHMSS 973
           999*********7787777776.78999************9*9********************************999877776655 PP
   S: 223  ...dnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
              +++++    +++  lv+g s gsi++  ++ + ll 
   Q: 974  ikeETPTCAVSVQKQGKLVTGFSNGSISLVSSKEDRLLE 1012
           666666666666688899999999999998777777766 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

WGIRNTEVTD LLTTELCLEE VDRCWKTSIG PAFVALIGDQ YGPCVVPSRI DEKEWEVLRA 60
RLTARPSDLE LVARHFRRDE NAVPPTYILQ APGTGEACEP EKATLTSVLR SGAQEARRLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGGTATTC GGAACACTGA AGTCACTGAC CTCTTGACCA CAGAACTCTG CTTGGAGGAG 60
GTTGACCGGT GTTGGAAAAC ATCCATAGGG CCAGCTTTTG TTGTGAGTGT CTCAGGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027417--P-loop_NTPase
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	76.21	0.00e+00	2263.00
IUUC-Apl-003467	Anas platyrhynchos	57.08	2.00e-80	291.00
IUUC-Ame-011400	Astyanax mexicanus	33.06	0.00e+00	779.00
IUUC-Bta-013223	Bos taurus	75.29	0.00e+00	1964.00
IUUC-Cel-018404	Caenorhabditis elegans	28.15	6.00e-64	240.00
IUUC-Cja-018773	Callithrix jacchus	77.82	0.00e+00	1432.00
IUUC-Cfa-020334	Canis familiaris	76.68	0.00e+00	2259.00
IUUC-Cpo-022316	Cavia porcellus	60.47	0.00e+00	1677.00
IUUC-Csa-023631	Chlorocebus sabaeus	90.03	0.00e+00	2674.00
IUUC-Cin-025646	Ciona intestinalis	28.21	2.00e-91	331.00
IUUC-Csv-026191	Ciona savignyi	22.11	1.00e-17	84.30
IUUC-Dre-028241	Danio rerio	33.33	0.00e+00	733.00
IUUC-Dno-029990	Dasypus novemcinctus	76.80	0.00e+00	674.00
IUUC-Dor-030869	Dipodomys ordii	48.67	9.00e-105	375.00
IUUC-Ete-033059	Echinops telfairi	82.24	0.00e+00	838.00
IUUC-Eca-033718	Equus caballus	73.66	0.00e+00	2159.00
IUUC-Fca-035748	Felis catus	74.98	0.00e+00	2042.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.12	2.00e-91	331.00
IUUC-Ggo-044551	Gorilla gorilla	84.24	0.00e+00	2484.00
IUUC-Hsa-046787	Homo sapiens	86.77	0.00e+00	2616.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	81.50	0.00e+00	1058.00
IUUC-Lch-049578	Latimeria chalumnae	42.65	0.00e+00	1170.00
IUUC-Loc-052039	Lepisosteus oculatus	36.98	0.00e+00	979.00
IUUC-Laf-054240	Loxodonta africana	75.31	0.00e+00	2269.00
IUUC-Meu-056591	Macropus eugenii	54.41	0.00e+00	953.00
IUUC-Mmr-061577	Microcebus murinus	73.66	0.00e+00	2163.00
IUUC-Mdo-062895	Monodelphis domestica	55.05	0.00e+00	1490.00
IUUC-Mmu-063866	Mus musculus	70.66	0.00e+00	2044.00
IUUC-Mpu-066510	Mustela putorius furo	75.42	0.00e+00	2254.00
IUUC-Mlu-067855	Myotis lucifugus	74.58	0.00e+00	2162.00
IUUC-Nle-069557	Nomascus leucogenys	81.66	0.00e+00	2388.00
IUUC-Opr-071196	Ochotona princeps	63.54	3.00e-175	609.00
IUUC-Ont-072070	Oreochromis niloticus	31.73	4.00e-104	373.00
IUUC-Oan-073437	Ornithorhynchus anatinus	50.33	0.00e+00	991.00
IUUC-Ocu-074941	Oryctolagus cuniculus	54.46	1.00e-26	112.00
IUUC-Ola-086624	Oryzias latipes	31.27	2.00e-159	556.00
IUUC-Oga-088313	Otolemur garnettii	77.23	0.00e+00	2063.00
IUUC-Oar-090123	Ovis aries	74.58	0.00e+00	2224.00
IUUC-Ptr-090552	Pan troglodytes	93.27	0.00e+00	1238.00
IUUC-Psi-093963	Pelodiscus sinensis	47.95	0.00e+00	1313.00
IUUC-Pfo-096197	Poecilia formosa	30.88	3.00e-176	613.00
IUUC-Pab-097755	Pongo abelii	91.96	0.00e+00	1038.00
IUUC-Pca-100809	Procavia capensis	74.34	0.00e+00	982.00
IUUC-Pva-102554	Pteropus vampyrus	79.85	0.00e+00	1063.00
IUUC-Rno-105174	Rattus norvegicus	65.55	0.00e+00	1823.00
IUUC-Sha-107304	Sarcophilus harrisii	55.15	0.00e+00	1656.00
IUUC-Sar-113168	Sorex araneus	65.87	0.00e+00	709.00
IUUC-Tru-118251	Takifugu rubripes	30.04	3.00e-78	287.00
IUUC-Tsy-119276	Tarsius syrichta	75.45	8.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence