iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022297

Ensembl Protein ID

ENSCPOP00000009628.2

UniProt Accession

H0VHJ2; H0VHJ2_CAVPO

Genbank Protein ID

ENSCPOP00000009628

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02042444

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000010726.3	ENSCPOT00000010824.2	ENSCPOP00000009628.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.80e-27	92.2	1609	1638
UBD/Beta-Prp	1.10e-43	149.5	1434	1645

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDl 30
           gH +++++++ ++ ++ +++dD t+++W +
   Q: 1609 GHDSPINAVCVNSAHIFTAADDRTVRIWKT 1638
           8********995599*************96 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  sg d +++Gs+d +ir++d+ +g       
   Q: 1434 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisSGqDLIITGSKDHYIRMFDVTEGALGTVsp 1519
           56789*********9.99*************************************98778*****************9998765466 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wd+++++ll++   +h+d +  l + +  + l+sg + g +klw++ t   v
   Q: 1520 thnFEPPHYDGIEALTIQG--DSLFSGSRDNGIKKWDIAQKDLLQQVPNAHKDWICALGVVPGHPVLLSGCRGGILKLWNMDTCVPV 1604
           7878999999999999999..99************************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgd 255
            +++gh+++++ v +   + ++ ++++D+++riW   +l+ ++
   Q: 1605 GEMKGHDSPINAVCVN--SAHIFTAADDRTVRIWkthNLQESQ 1645
           ***********88888..****************666666555 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

ISCRIRPQLA KEKIEGCHIC TSVTPGEPQV FLGKDKAFTF DYVFDIDSQQ EQIYTQCIEK 60
LIEGCFEGYN ATVFAYGQTG AGKTYTMGTG FDVNITEEEQ GIISRAVKHL FKSIEEKKHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCTTGCA GAATAAGACC ACAGCTTGCC AAAGAAAAGA TTGAAGGATG CCATATTTGT 60
ACATCGGTCA CTCCAGGAGA GCCCCAGGTC TTCCTAGGGA AAGATAAGGC CTTTACTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	92.60	0.00e+00	2966.00
IUUC-Apl-003353	Anas platyrhynchos	83.71	0.00e+00	2599.00
IUUC-Aca-004467	Anolis carolinensis	82.91	0.00e+00	2698.00
IUUC-Ame-011430	Astyanax mexicanus	66.05	0.00e+00	1287.00
IUUC-Bta-013485	Bos taurus	91.93	0.00e+00	2878.00
IUUC-Cel-018402	Caenorhabditis elegans	53.54	1.00e-147	518.00
IUUC-Cja-019385	Callithrix jacchus	90.46	0.00e+00	2872.00
IUUC-Cfa-020986	Canis familiaris	92.56	0.00e+00	2924.00
IUUC-Csa-023685	Chlorocebus sabaeus	92.49	0.00e+00	2922.00
IUUC-Cho-024531	Choloepus hoffmanni	89.44	0.00e+00	1084.00
IUUC-Cin-025160	Ciona intestinalis	46.73	2.00e-86	312.00
IUUC-Csv-026158	Ciona savignyi	57.43	2.00e-177	617.00
IUUC-Dre-028532	Danio rerio	67.36	0.00e+00	2091.00
IUUC-Dno-029972	Dasypus novemcinctus	90.22	0.00e+00	2734.00
IUUC-Ete-032872	Echinops telfairi	77.49	0.00e+00	1003.00
IUUC-Eca-033518	Equus caballus	92.42	0.00e+00	2933.00
IUUC-Fca-036197	Felis catus	92.44	0.00e+00	2922.00
IUUC-Fal-037534	Ficedula albicollis	82.96	0.00e+00	1644.00
IUUC-Gmo-039407	Gadus morhua	65.57	0.00e+00	1342.00
IUUC-Gga-040687	Gallus gallus	82.35	0.00e+00	2570.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.75	0.00e+00	2171.00
IUUC-Ggo-044457	Gorilla gorilla	92.61	0.00e+00	2916.00
IUUC-Hsa-046372	Homo sapiens	92.72	0.00e+00	2925.00
IUUC-Lch-049786	Latimeria chalumnae	59.54	0.00e+00	1872.00
IUUC-Loc-052689	Lepisosteus oculatus	74.31	0.00e+00	2350.00
IUUC-Laf-054018	Loxodonta africana	87.90	0.00e+00	2707.00
IUUC-Mcc-055558	Macaca mulatta	92.48	0.00e+00	2933.00
IUUC-Meu-056080	Macropus eugenii	85.84	0.00e+00	961.00
IUUC-Mga-059283	Meleagris gallopavo	81.91	0.00e+00	2532.00
IUUC-Mmr-060773	Microcebus murinus	90.78	0.00e+00	2833.00
IUUC-Mdo-062688	Monodelphis domestica	87.78	0.00e+00	2569.00
IUUC-Mmu-063997	Mus musculus	91.03	0.00e+00	2816.00
IUUC-Mpu-066354	Mustela putorius furo	90.67	0.00e+00	2894.00
IUUC-Mlu-067599	Myotis lucifugus	91.55	0.00e+00	2871.00
IUUC-Nle-069477	Nomascus leucogenys	92.66	0.00e+00	2927.00
IUUC-Opr-070188	Ochotona princeps	83.35	0.00e+00	1617.00
IUUC-Ont-071717	Oreochromis niloticus	63.31	0.00e+00	1896.00
IUUC-Oan-073055	Ornithorhynchus anatinus	87.98	0.00e+00	2632.00
IUUC-Ocu-074302	Oryctolagus cuniculus	89.69	0.00e+00	2855.00
IUUC-Ola-087491	Oryzias latipes	64.17	0.00e+00	1864.00
IUUC-Oga-088799	Otolemur garnettii	90.69	0.00e+00	2614.00
IUUC-Oar-089629	Ovis aries	90.52	0.00e+00	2865.00
IUUC-Pan-092214	Papio anubis	91.11	0.00e+00	2904.00
IUUC-Psi-093757	Pelodiscus sinensis	81.06	0.00e+00	2479.00
IUUC-Pfo-096978	Poecilia formosa	65.75	0.00e+00	1313.00
IUUC-Pab-097984	Pongo abelii	92.54	0.00e+00	2891.00
IUUC-Pca-101061	Procavia capensis	77.65	0.00e+00	1415.00
IUUC-Pva-102306	Pteropus vampyrus	89.12	0.00e+00	2800.00
IUUC-Rno-105354	Rattus norvegicus	89.20	0.00e+00	2773.00
IUUC-Sha-106938	Sarcophilus harrisii	87.28	0.00e+00	1774.00
IUUC-Ssc-115810	Sus scrofa	91.42	0.00e+00	2862.00
IUUC-Tgu-117076	Taeniopygia guttata	79.77	0.00e+00	1551.00
IUUC-Tru-118091	Takifugu rubripes	65.37	0.00e+00	1248.00
IUUC-Tsy-119020	Tarsius syrichta	91.20	0.00e+00	2902.00
IUUC-Tni-120813	Tetraodon nigroviridis	62.56	0.00e+00	1240.00
IUUC-Tbe-127494	Tupaia belangeri	76.88	0.00e+00	992.00
IUUC-Ttr-128393	Tursiops truncatus	84.41	0.00e+00	2646.00
IUUC-Vpa-130675	Vicugna pacos	79.00	0.00e+00	740.00
IUUC-Xtr-132829	Xenopus tropicalis	77.64	0.00e+00	2486.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence