iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074302

Ensembl Protein ID

ENSOCUP00000014309.3

UniProt Accession

G1TC28; G1TC28_RABIT

Genbank Protein ID

ENSOCUP00000014309

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02045217

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000016630.3	ENSOCUT00000016643.3	ENSOCUP00000014309.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-30	101.6	1338	1372
UBD/Beta-Prp	1.20e-44	152.7	1442	1655

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1338 GHTKAVLCVDATDDLLFTGSKDRTCKVWNLVTGQE 1372
           8********9878*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  sg d +v+Gs+d +i+++d+ +g       
   Q: 1442 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisSGqDLIVTGSKDHYIKMFDVTEGALGTVsp 1527
           56789*********9.99*************************************98778*****************9998765467 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l + +  + l+sg + g +klw++ t   v
   Q: 1528 thnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALGVVPGHPVLLSGCRGGVLKLWNVDTFAPV 1612
           7889999999999999999..7799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1613 GEMKGHDSPINAICVN--STHIFTAADDRTVRIWkarNLQDGQIS 1655
           ***********99888..****************99999988876 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MWGSADESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIDSQ 60
QQQIYTQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIMEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGGGCT CGGCGGACGA GAGCTCCGTG CGGGTGGCTG TCAGGTGAGG AGCTGCGCGG 60
GCGCGGGCGC GGGCGGAGGG CGCGCGGCTG TGGAAACTGA GGCAGCGGGT GGCCCGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	92.80	0.00e+00	3008.00
IUUC-Apl-003353	Anas platyrhynchos	82.73	0.00e+00	2610.00
IUUC-Aca-004467	Anolis carolinensis	81.46	0.00e+00	2695.00
IUUC-Ame-011237	Astyanax mexicanus	65.47	0.00e+00	2028.00
IUUC-Bta-013485	Bos taurus	91.51	0.00e+00	2906.00
IUUC-Cja-019385	Callithrix jacchus	93.08	0.00e+00	2900.00
IUUC-Cfa-020986	Canis familiaris	92.82	0.00e+00	2950.00
IUUC-Cpo-022297	Cavia porcellus	90.23	0.00e+00	2832.00
IUUC-Csa-023685	Chlorocebus sabaeus	92.44	0.00e+00	2955.00
IUUC-Cho-024531	Choloepus hoffmanni	86.45	0.00e+00	1080.00
IUUC-Cin-025160	Ciona intestinalis	47.66	3.00e-88	319.00
IUUC-Dno-029972	Dasypus novemcinctus	89.41	0.00e+00	2747.00
IUUC-Ete-032872	Echinops telfairi	79.20	0.00e+00	1033.00
IUUC-Eca-033518	Equus caballus	91.97	0.00e+00	2954.00
IUUC-Fca-036197	Felis catus	92.13	0.00e+00	2948.00
IUUC-Fal-037534	Ficedula albicollis	81.35	0.00e+00	2618.00
IUUC-Gmo-039407	Gadus morhua	65.65	0.00e+00	1904.00
IUUC-Gga-040687	Gallus gallus	80.99	0.00e+00	2564.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.31	0.00e+00	2155.00
IUUC-Ggo-044457	Gorilla gorilla	92.21	0.00e+00	2933.00
IUUC-Hsa-046372	Homo sapiens	92.68	0.00e+00	2967.00
IUUC-Lch-049786	Latimeria chalumnae	59.26	0.00e+00	1880.00
IUUC-Loc-052689	Lepisosteus oculatus	73.23	0.00e+00	2338.00
IUUC-Laf-054018	Loxodonta africana	87.73	0.00e+00	2724.00
IUUC-Mcc-055558	Macaca mulatta	92.32	0.00e+00	2969.00
IUUC-Meu-056080	Macropus eugenii	87.80	0.00e+00	977.00
IUUC-Mga-059283	Meleagris gallopavo	80.84	0.00e+00	2532.00
IUUC-Mmr-060773	Microcebus murinus	90.95	0.00e+00	2879.00
IUUC-Mdo-062688	Monodelphis domestica	88.00	0.00e+00	2569.00
IUUC-Mmu-063997	Mus musculus	90.37	0.00e+00	2840.00
IUUC-Mpu-066354	Mustela putorius furo	91.55	0.00e+00	2955.00
IUUC-Mlu-067599	Myotis lucifugus	91.09	0.00e+00	2896.00
IUUC-Nle-069477	Nomascus leucogenys	92.38	0.00e+00	2965.00
IUUC-Opr-070188	Ochotona princeps	85.96	0.00e+00	1652.00
IUUC-Ont-071938	Oreochromis niloticus	68.37	0.00e+00	2168.00
IUUC-Oan-073055	Ornithorhynchus anatinus	86.24	0.00e+00	2601.00
IUUC-Ola-086604	Oryzias latipes	66.10	0.00e+00	2093.00
IUUC-Oga-088799	Otolemur garnettii	90.85	0.00e+00	2624.00
IUUC-Oar-089629	Ovis aries	89.72	0.00e+00	2883.00
IUUC-Pan-092214	Papio anubis	91.25	0.00e+00	2946.00
IUUC-Psi-093757	Pelodiscus sinensis	78.72	0.00e+00	2466.00
IUUC-Pfo-097448	Poecilia formosa	61.62	0.00e+00	1888.00
IUUC-Pab-097984	Pongo abelii	92.50	0.00e+00	2938.00
IUUC-Pca-101061	Procavia capensis	76.64	0.00e+00	1390.00
IUUC-Pva-102306	Pteropus vampyrus	89.94	0.00e+00	2845.00
IUUC-Rno-105354	Rattus norvegicus	89.03	0.00e+00	2773.00
IUUC-Sha-106938	Sarcophilus harrisii	85.70	0.00e+00	1751.00
IUUC-Ssc-115810	Sus scrofa	91.26	0.00e+00	2899.00
IUUC-Tgu-117076	Taeniopygia guttata	79.63	0.00e+00	2495.00
IUUC-Tru-117904	Takifugu rubripes	57.57	0.00e+00	1073.00
IUUC-Tsy-119020	Tarsius syrichta	90.69	0.00e+00	2915.00
IUUC-Tni-120813	Tetraodon nigroviridis	65.84	0.00e+00	2093.00
IUUC-Tbe-127494	Tupaia belangeri	76.00	0.00e+00	984.00
IUUC-Ttr-128393	Tursiops truncatus	84.29	0.00e+00	2674.00
IUUC-Vpa-130675	Vicugna pacos	80.72	0.00e+00	760.00
IUUC-Xtr-132829	Xenopus tropicalis	77.67	0.00e+00	2497.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence