iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047553

Ensembl Protein ID

MLOC_54618.1

UniProt Accession

F2CRB4; F2CRB4_HORVV

Genbank Protein ID

BAJ85385.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

AK354166

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_54618	MLOC_54618.1	MLOC_54618.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-25	89.1	50	87
UBD/Beta-Prp	3.60e-40	139.1	6	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH++ v++++   ++t+l++Gs D t k+WD++tg+ l
   Q: 50   GHNGAVWSCDVsrHSTRLITGSADQTAKLWDVKTGKEL 87
           8**********9644*******************9876 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee............. 131
           ++ghe + t +k+++dg++l ++++D+t  vw  ++g+ + t++gh+  v+s+++s+ + +l++Gs+d+t+++wd++tg++l +             
   Q: 6    MKGHERPLTFLKYNRDGDLLFSCAKDHTPTVWYADNGDRLGTYRGHNGAVWSCDVSRHSTRLITGSADQTAKLWDVKTGKELFTfrfdaparsvdla 102
           48999999999*****99**************999********************999999******************9999999999******** PP
   S: 132  ......................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsf 188
                                                 + sg +g +n +v+ p ++ +++++ D t+r+Wd++tgkll++   + gh++++ sls 
   Q: 103  igdhlavittdsfmgnmptaqvkriaedlqdqteesalVISGITGRINRAVWGPGNRTIITAGEDATIRIWDSETGKLLKESdkEVGHQKAISSLSK 199
           **********************************************************************************99667********** PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs.sDg 244
           + +  ++++gsld++ klwd +t + ++t+    ++v+ v+ sp  +++v g+ +D 
   Q: 200  SLDWSHFLTGSLDKSAKLWDARTLTLIKTYVTE-RPVNAVDISPTLDHVVIGGgQDA 255
           *****************************9975.57888888866666666552543 PP

Organism

Hordeum vulgare

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHTPTVWYAD NGDRLGTYRG HNGAVWSCDV 60
SRHSTRLITG SADQTAKLWD VKTGKELFTF RFDAPARSVD LAIGDHLAVI TTDSFMGNMP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCACTAG CCACCTCCCG CAGCACAGCT CCCCGCTAGA CGGCAACCTA GGCGCATGCT 60
GTTTCACCCG TAGTTCTTGT TGGGCCGAAA CCCAGCCCAG CCTTCGTGCT TAATACAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	69.90	1.00e-75	275.00
IUUC-Aml-001321	Ailuropoda melanoleuca	46.15	1.00e-86	311.00
IUUC-Atr-002468	Amborella trichopoda	73.75	3.00e-97	346.00
IUUC-Apl-003841	Anas platyrhynchos	46.32	4.00e-87	313.00
IUUC-Aca-005123	Anolis carolinensis	46.01	4.00e-88	316.00
IUUC-Aly-005473	Arabidopsis lyrata	77.13	3.00e-152	529.00
IUUC-Ath-007094	Arabidopsis thaliana	76.52	1.00e-151	527.00
IUUC-Ago-008000	Ashbya gossypii	41.87	1.00e-73	268.00
IUUC-Acl-008098	Aspergillus clavatus	45.62	3.00e-81	293.00
IUUC-Afl-008494	Aspergillus flavus	46.46	2.00e-83	301.00
IUUC-Afu-009080	Aspergillus fumigatus	44.71	6.00e-80	289.00
IUUC-Ani-009230	Aspergillus nidulans	46.18	3.00e-82	296.00
IUUC-Aor-010114	Aspergillus oryzae	46.46	2.00e-83	301.00
IUUC-Ate-010285	Aspergillus terreus	44.95	2.00e-81	294.00
IUUC-Ame-011534	Astyanax mexicanus	46.34	2.00e-88	317.00
IUUC-Bgr-012121	Blumeria graminis	42.59	2.00e-74	270.00
IUUC-Bta-013143	Bos taurus	46.32	3.00e-87	313.00
IUUC-Bci-013950	Botrytis cinerea	46.67	1.00e-83	301.00
IUUC-Bdi-015019	Brachypodium distachyon	95.40	0.00e+00	649.00
IUUC-Bol-015709	Brassica oleracea	75.76	3.00e-150	524.00
IUUC-Bra-017760	Brassica rapa	75.76	1.00e-151	528.00
IUUC-Cel-018226	Caenorhabditis elegans	39.75	2.00e-71	261.00
IUUC-Cja-019741	Callithrix jacchus	46.32	2.00e-87	314.00
IUUC-Cfa-021204	Canis familiaris	46.15	1.00e-86	311.00
IUUC-Cpo-021661	Cavia porcellus	45.85	2.00e-86	310.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	52.45	5.00e-102	362.00
IUUC-Csa-024038	Chlorocebus sabaeus	46.32	2.00e-87	314.00
IUUC-Cin-025597	Ciona intestinalis	47.24	2.00e-86	311.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.48	7.00e-78	282.00
IUUC-Cne-026838	Cryptococcus neoformans	44.11	1.00e-77	281.00
IUUC-Cme-027304	Cyanidioschyzon merolae	53.70	3.00e-91	327.00
IUUC-Dre-028567	Danio rerio	46.01	3.00e-89	320.00
IUUC-Dno-029171	Dasypus novemcinctus	46.15	4.00e-86	310.00
IUUC-Dor-030257	Dipodomys ordii	32.95	3.00e-26	110.00
IUUC-Dse-031191	Dothistroma septosporum	45.02	8.00e-81	292.00
IUUC-Dme-031879	Drosophila melanogaster	48.31	2.00e-88	317.00
IUUC-Ete-032336	Echinops telfairi	38.71	1.00e-42	164.00
IUUC-Eca-033259	Equus caballus	46.15	2.00e-86	311.00
IUUC-Eeu-035153	Erinaceus europaeus	43.07	1.00e-27	115.00
IUUC-Fca-036489	Felis catus	46.15	2.00e-86	311.00
IUUC-Fal-037485	Ficedula albicollis	46.01	6.00e-87	312.00
IUUC-Fox-037860	Fusarium oxysporum	45.57	5.00e-80	289.00
IUUC-Fso-038188	Fusarium solani	45.57	6.00e-78	282.00
IUUC-Gmo-039311	Gadus morhua	45.54	1.00e-86	311.00
IUUC-Ggr-040045	Gaeumannomyces graminis	45.85	2.00e-80	290.00
IUUC-Gga-040645	Gallus gallus	45.51	9.00e-86	308.00
IUUC-Gac-042086	Gasterosteus aculeatus	46.01	4.00e-87	313.00
IUUC-Gma-043246	Glycine max	81.65	1.00e-159	554.00
IUUC-Ggo-045578	Gorilla gorilla	46.32	2.00e-87	314.00
IUUC-Hsa-046734	Homo sapiens	46.32	2.00e-87	314.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	46.15	2.00e-86	310.00
IUUC-Kpa-049325	Komagataella pastoris	45.26	3.00e-80	290.00
IUUC-Lch-049620	Latimeria chalumnae	45.85	2.00e-78	284.00
IUUC-Lpe-051338	Leersia perrieri	87.14	4.00e-163	565.00
IUUC-Loc-052094	Lepisosteus oculatus	41.72	1.00e-74	271.00
IUUC-Lma-053047	Leptosphaeria maculans	46.15	8.00e-82	295.00
IUUC-Laf-053801	Loxodonta africana	46.08	5.00e-84	303.00
IUUC-Mcc-055498	Macaca mulatta	41.41	1.00e-69	254.00
IUUC-Meu-056729	Macropus eugenii	42.81	8.00e-78	282.00
IUUC-Mor-057025	Magnaporthe oryzae	45.09	5.00e-78	283.00
IUUC-Mpo-057511	Magnaporthe poae	46.63	1.00e-80	291.00
IUUC-Mtr-058051	Medicago truncatula	80.98	6.00e-160	555.00
IUUC-Mla-059061	Melampsora laricipopulina	43.56	3.00e-78	283.00
IUUC-Mga-059229	Meleagris gallopavo	45.87	9.00e-85	305.00
IUUC-Mvi-060399	Microbotryum violaceum	42.86	1.00e-73	268.00
IUUC-Mmr-060764	Microcebus murinus	46.32	9.00e-88	315.00
IUUC-Mdo-062088	Monodelphis domestica	45.71	5.00e-86	309.00
IUUC-Mmu-064304	Mus musculus	46.01	2.00e-87	313.00
IUUC-Mac-065520	Musa acuminata	80.69	1.00e-158	551.00
IUUC-Mpu-066340	Mustela putorius furo	46.15	2.00e-86	311.00
IUUC-Mlu-067111	Myotis lucifugus	46.01	9.00e-87	311.00
IUUC-Nfi-068478	Neosartorya fischeri	44.71	1.00e-80	291.00
IUUC-Ncr-068820	Neurospora crassa	46.15	1.00e-79	288.00
IUUC-Nle-069903	Nomascus leucogenys	46.15	9.00e-87	311.00
IUUC-Opr-070221	Ochotona princeps	45.09	2.00e-84	304.00
IUUC-Ont-071765	Oreochromis niloticus	46.63	6.00e-90	322.00
IUUC-Oan-073660	Ornithorhynchus anatinus	44.18	2.00e-72	264.00
IUUC-Ocu-074039	Oryctolagus cuniculus	46.15	1.00e-86	311.00
IUUC-Oba-075395	Oryza barthii	81.29	9.00e-155	537.00
IUUC-Obr-076334	Oryza brachyantha	86.20	2.00e-166	577.00
IUUC-Ogl-077751	Oryza glaberrima	90.18	2.00e-177	613.00
IUUC-Ogu-078207	Oryza glumaepatula	89.54	4.00e-175	605.00
IUUC-Oin-079878	Oryza indica	89.88	2.00e-176	609.00
IUUC-Olo-080677	Oryza longistaminata	77.37	3.00e-168	582.00
IUUC-Ome-081228	Oryza meridionalis	69.58	1.00e-89	321.00
IUUC-Oni-082411	Oryza nivara	78.53	3.00e-148	516.00
IUUC-Opu-083136	Oryza punctata	89.88	5.00e-177	612.00
IUUC-Oru-084916	Oryza rufipogon	87.46	1.00e-174	603.00
IUUC-Osa-085776	Oryza sativa	90.18	2.00e-177	613.00
IUUC-Ola-087053	Oryzias latipes	46.63	5.00e-88	316.00
IUUC-Olu-087602	Ostreococcus lucimarinus	60.86	1.00e-116	411.00
IUUC-Oga-088154	Otolemur garnettii	45.85	1.00e-85	308.00
IUUC-Oar-089915	Ovis aries	46.15	1.00e-86	311.00
IUUC-Ptr-091124	Pan troglodytes	37.80	1.00e-59	221.00
IUUC-Pan-092035	Papio anubis	46.32	2.00e-87	314.00
IUUC-Psi-094096	Pelodiscus sinensis	44.50	5.00e-53	199.00
IUUC-Pno-094988	Phaeosphaeria nodorum	42.77	1.00e-70	258.00
IUUC-Ppa-095536	Physcomitrella patens	74.54	3.00e-146	509.00
IUUC-Pfo-096101	Poecilia formosa	45.71	2.00e-88	317.00
IUUC-Pab-097726	Pongo abelii	46.32	2.00e-87	314.00
IUUC-Pop-099617	Populus trichocarpa	78.53	3.00e-156	543.00
IUUC-Pca-101014	Procavia capensis	46.32	1.00e-87	314.00
IUUC-Ppe-101320	Prunus persica	81.29	5.00e-160	555.00
IUUC-Pva-102789	Pteropus vampyrus	42.64	6.00e-76	276.00
IUUC-Pgr-103479	Puccinia graminis	43.25	2.00e-77	281.00
IUUC-Ptt-103981	Puccinia triticina	43.25	3.00e-78	283.00
IUUC-Pte-104278	Pyrenophora teres	44.31	8.00e-78	282.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	44.31	8.00e-78	282.00
IUUC-Rno-105867	Rattus norvegicus	43.03	3.00e-72	263.00
IUUC-Sce-106251	Saccharomyces cerevisiae	41.27	2.00e-72	264.00
IUUC-Sha-107039	Sarcophilus harrisii	45.57	4.00e-86	310.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	43.87	2.00e-80	290.00
IUUC-Spo-108314	Schizosaccharomyces pombe	45.43	2.00e-84	304.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	46.67	2.00e-83	301.00
IUUC-Smo-108728	Selaginella moellendorffii	72.70	6.00e-143	498.00
IUUC-Sit-110801	Setaria italica	89.88	8.00e-177	611.00
IUUC-Sly-111326	Solanum lycopersicum	77.61	2.00e-154	536.00
IUUC-Stu-112458	Solanum tuberosum	79.45	9.00e-157	544.00
IUUC-Sbi-114063	Sorghum bicolor	89.26	3.00e-176	609.00
IUUC-Sre-115096	Sporisorium reilianum	45.43	1.00e-76	278.00
IUUC-Ssc-116080	Sus scrofa	46.32	2.00e-87	313.00
IUUC-Tgu-116988	Taeniopygia guttata	46.15	6.00e-87	312.00
IUUC-Tru-118766	Takifugu rubripes	46.01	2.00e-88	317.00
IUUC-Tni-120197	Tetraodon nigroviridis	46.32	6.00e-89	319.00
IUUC-Tca-121316	Theobroma cacao	82.21	1.00e-160	557.00
IUUC-Tre-122097	Trichoderma reesei	47.09	5.00e-82	296.00
IUUC-Tvi-122442	Trichoderma virens	46.48	6.00e-81	292.00
IUUC-Tae-125800	Triticum aestivum	99.69	0.00e+00	673.00
IUUC-Tur-126334	Triticum urartu	86.20	1.00e-163	567.00
IUUC-Tme-127038	Tuber melanosporum	46.63	1.00e-85	308.00
IUUC-Ttr-128659	Tursiops truncatus	43.87	3.00e-68	250.00
IUUC-Uma-129464	Ustilago maydis	45.99	2.00e-76	278.00
IUUC-Vda-129841	Verticillium dahliae	45.23	1.00e-78	284.00
IUUC-Vvi-131076	Vitis vinifera	80.67	3.00e-160	556.00
IUUC-Xtr-132395	Xenopus tropicalis	47.85	4.00e-89	320.00
IUUC-Xma-133383	Xiphophorus maculatus	45.71	4.00e-88	316.00
IUUC-Yli-134586	Yarrowia lipolytica	44.82	5.00e-72	263.00
IUUC-Zma-135904	Zea mays	89.57	3.00e-177	612.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence