iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-083413

Ensembl Protein ID

OPUNC05G08050.1

UniProt Accession

A0A0E0L091; A0A0E0L091_ORYPU

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC05G08050	OPUNC05G08050.1	OPUNC05G08050.1
OPUNC05G08050	OPUNC05G08050.3	OPUNC05G08050.3
OPUNC05G08050	OPUNC05G08050.4	OPUNC05G08050.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-24	84.1	50	86
UBD/Beta-Prp	3.20e-40	139.1	6	254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v++++   d t+l++Gs D t k+WD+ tg+ 
   Q: 50   GHNGAVWSCDVsRDsTRLITGSADQTAKLWDVQTGTE 86
           8***********777******************9986 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......... 131
           ++ghe + t +++++dg++l ++++D+t +vw  ++g+ + t++gh+  v+s+++s+++ +l++Gs+d+t+++wd++tg++l +          
   Q: 6    MKGHERPLTFLRYNRDGDLLFSCAKDHTPNVWFADNGDRLGTYRGHNGAVWSCDVSRDSTRLITGSADQTAKLWDVQTGTELFTfrfdaparsv 99
           489******************************************************************************************* PP
   S: 132  .........................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...tgghtd 181
                                                    + sg +g +n +v+ p ++ +++++ D t+r+Wd +tg++l++    + gh++
   Q: 100  efaigdglavittdnfmdnvptaqvkriaddpddqseeallVISGIKGRINRAVWGPLNKTIITAGEDATIRIWDTETGTCLKESdkeQ-GHQK 192
           **************************************************************************************955.5*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs.sD 243
            ++sls + +  ++++gsld++ klwd +t + ++t+    ++v+ v+ sp  +++v g+ +D
   Q: 193  TITSLSKSADWSHFLTGSLDKSAKLWDTRTLTLIKTYVTE-RPVNAVDISPLLDHVVIGGgQD 254
           ************************************9875.4666666665444444443144 PP

Organism

Oryza punctata

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLRYNR DGDLLFSCAK DHTPNVWFAD NGDRLGTYRG HNGAVWSCDV 60
SRDSTRLITG SADQTAKLWD VQTGTELFTF RFDAPARSVE FAIGDGLAVI TTDNFMDNVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACAAAGCC CCCACAACCC ACCCGCGAGC TAGGGTTTTT CCTCACCGCC GCAACGCCAC 60
CCACCTCCCT AACCCTAACC CGACCCATCC TCCCCGGCGG CGGCGGCGGC GGCGAGGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	91.94	3.00e-64	238.00
IUUC-Dor-030257	Dipodomys ordii	32.39	9.00e-26	110.00
IUUC-Ete-032336	Echinops telfairi	38.89	2.00e-41	161.00
IUUC-Ome-081228	Oryza meridionalis	75.42	7.00e-99	352.00
IUUC-Pva-102789	Pteropus vampyrus	38.67	3.00e-68	251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence