iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052312

Ensembl Protein ID

ENSLOCP00000007089.1

UniProt Accession

W5MFD0; W5MFD0_LEPOC

Genbank Protein ID

ENSLOCP00000007089

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01005837

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005871.1	ENSLOCT00000007097.1	ENSLOCP00000007089.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.20e-06	26.4	14	77
E3 activity/RING/RING	2.50e-06	28.1	18	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrli 65
             f Cp+ ++ Mr+Pv ++ +G+ +  ++++++l+s g  +cP ++ pl+  ++ P   l + i
   Q: 14   RRFQCPLCNKAMREPVQVStCGHRFCDTCLQEFLSSEGVfKCPEDQLPLDYAKIYPDPDLEQQI 77
           67***************999**************9998889**********9999998887776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C++C   +++++ v  CgH f+ +Clq +     ss + f+CP +
   Q: 18   CPLCNKAMREPVQVSTCGHRFCDTCLQEF----LSSEGVFKCPED 58
           ****999999777888**********999....89********65 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRFQCPL CNKAMREPVQ VSTCGHRFCD TCLQEFLSSE GVFKCPEDQL 60
PLDYAKIYPD PDLEQQILSL SIRCIHSEEG CRWTGQMKQL QSHFSTCAFN VIPCPNRCAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGGCT TCGATTACAA GTTTCTGGAG AAGCCGAAGA GGCGGTTCCA GTGCCCTCTG 60
TGTAATAAAG CCATGCGAGA ACCCGTGCAG GTATCTACCT GCGGACACCG ATTCTGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00917--MATH
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	37.14	2.00e-08	53.10
IUUC-Aml-001287	Ailuropoda melanoleuca	76.38	0.00e+00	753.00
IUUC-Ame-011530	Astyanax mexicanus	91.30	0.00e+00	884.00
IUUC-Bta-013582	Bos taurus	77.07	0.00e+00	764.00
IUUC-Bdi-014617	Brachypodium distachyon	25.71	4.00e-08	54.30
IUUC-Bol-016391	Brassica oleracea	28.81	6.00e-07	49.30
IUUC-Cfa-020133	Canis familiaris	73.89	0.00e+00	710.00
IUUC-Cpo-022021	Cavia porcellus	77.28	0.00e+00	768.00
IUUC-Csa-023199	Chlorocebus sabaeus	77.07	0.00e+00	766.00
IUUC-Cne-026870	Cryptococcus neoformans	25.00	2.00e-20	94.40
IUUC-Dre-028193	Danio rerio	91.93	0.00e+00	886.00
IUUC-Dno-028917	Dasypus novemcinctus	77.07	0.00e+00	767.00
IUUC-Ete-032433	Echinops telfairi	76.86	0.00e+00	761.00
IUUC-Fca-036155	Felis catus	77.71	0.00e+00	770.00
IUUC-Gmo-038860	Gadus morhua	91.30	0.00e+00	879.00
IUUC-Gga-041052	Gallus gallus	81.32	0.00e+00	840.00
IUUC-Gac-041489	Gasterosteus aculeatus	91.08	0.00e+00	882.00
IUUC-Gma-043859	Glycine max	30.00	2.00e-08	55.10
IUUC-Ggo-044996	Gorilla gorilla	77.07	0.00e+00	766.00
IUUC-Hsa-046252	Homo sapiens	77.28	0.00e+00	768.00
IUUC-Hvu-047095	Hordeum vulgare	27.05	4.00e-08	54.30
IUUC-Itr-048232	Ictidomys tridecemlineatus	77.28	0.00e+00	767.00
IUUC-Kpa-049340	Komagataella pastoris	29.15	1.00e-17	84.30
IUUC-Laf-054376	Loxodonta africana	77.28	0.00e+00	768.00
IUUC-Mcc-055684	Macaca mulatta	77.07	0.00e+00	766.00
IUUC-Mtr-057807	Medicago truncatula	26.98	1.00e-07	52.80
IUUC-Mmr-061198	Microcebus murinus	77.49	0.00e+00	769.00
IUUC-Mdo-062585	Monodelphis domestica	77.07	0.00e+00	764.00
IUUC-Mmu-064303	Mus musculus	77.28	0.00e+00	770.00
IUUC-Mac-064547	Musa acuminata	28.69	5.00e-08	53.90
IUUC-Mpu-066854	Mustela putorius furo	77.49	0.00e+00	769.00
IUUC-Nle-070098	Nomascus leucogenys	76.65	0.00e+00	761.00
IUUC-Ont-071518	Oreochromis niloticus	91.30	0.00e+00	882.00
IUUC-Ocu-073841	Oryctolagus cuniculus	76.86	0.00e+00	763.00
IUUC-Ola-086674	Oryzias latipes	90.66	0.00e+00	877.00
IUUC-Oga-088510	Otolemur garnettii	76.86	0.00e+00	763.00
IUUC-Oar-089225	Ovis aries	74.52	0.00e+00	728.00
IUUC-Pan-092725	Papio anubis	77.07	0.00e+00	766.00
IUUC-Pfo-096341	Poecilia formosa	90.45	0.00e+00	876.00
IUUC-Ppe-101708	Prunus persica	29.93	7.00e-10	60.50
IUUC-Pva-103131	Pteropus vampyrus	74.05	2.00e-112	399.00
IUUC-Rno-105996	Rattus norvegicus	77.49	0.00e+00	771.00
IUUC-Sit-110103	Setaria italica	27.05	9.00e-08	53.10
IUUC-Sly-111800	Solanum lycopersicum	31.67	9.00e-09	56.60
IUUC-Sbi-114841	Sorghum bicolor	27.05	2.00e-08	55.50
IUUC-Tru-117602	Takifugu rubripes	89.60	0.00e+00	875.00
IUUC-Tca-121454	Theobroma cacao	30.00	1.00e-08	56.20
IUUC-Tae-123531	Triticum aestivum	25.41	8.00e-08	53.10
IUUC-Tur-126325	Triticum urartu	27.05	3.00e-08	54.30
IUUC-Ttr-128370	Tursiops truncatus	77.87	2.00e-173	601.00
IUUC-Vvi-131592	Vitis vinifera	30.00	6.00e-09	57.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence