iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063035

UUCD1 version

UUC-MoD-00191

Ensembl Protein ID

ENSMODP00000005284.2

UniProt Accession

F6SY20; F6SY20_MONDO

Protein Name

Uncharacterized protein

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004289.2	ENSMODT00000005398.2	ENSMODP00000005284.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	44.68	3.00e-04	45.10	IUUC-Ath-007510
E3 activity/RING/RING	92.24	0.00e+00	1893.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTTTGAA AGATTTTGAT TCCAGTGGAA TCTGTGCTTT AGATTTTTTG TGTTGTGAAT 60
TGTAACTACT TAAGCAATGC CTGTACAAGC TCCGCAATGG ACGGATTTCC TCTCCTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	91.98	0.00e+00	1858.00
IUUC-Apl-003290	Anas platyrhynchos	86.31	0.00e+00	1806.00
IUUC-Aca-004905	Anolis carolinensis	83.84	0.00e+00	1732.00
IUUC-Aly-006116	Arabidopsis lyrata	44.68	4.00e-06	45.10
IUUC-Ath-007510	Arabidopsis thaliana	44.68	4.00e-06	45.10
IUUC-Ame-011475	Astyanax mexicanus	78.57	0.00e+00	912.00
IUUC-Cja-019907	Callithrix jacchus	91.98	0.00e+00	1881.00
IUUC-Cfa-020679	Canis familiaris	91.36	0.00e+00	1823.00
IUUC-Cpo-022110	Cavia porcellus	88.21	0.00e+00	1862.00
IUUC-Csa-024166	Chlorocebus sabaeus	92.55	0.00e+00	1814.00
IUUC-Dno-029870	Dasypus novemcinctus	88.91	0.00e+00	893.00
IUUC-Dor-030934	Dipodomys ordii	82.67	0.00e+00	1402.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	2.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	92.57	0.00e+00	1313.00
IUUC-Eca-033236	Equus caballus	91.45	0.00e+00	1812.00
IUUC-Eeu-035091	Erinaceus europaeus	82.37	0.00e+00	868.00
IUUC-Fca-035773	Felis catus	92.25	0.00e+00	1835.00
IUUC-Fal-036972	Ficedula albicollis	85.23	0.00e+00	1800.00
IUUC-Gmo-039303	Gadus morhua	79.90	0.00e+00	894.00
IUUC-Ggo-044691	Gorilla gorilla	86.58	0.00e+00	1729.00
IUUC-Hsa-046163	Homo sapiens	92.24	0.00e+00	1885.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	86.41	0.00e+00	948.00
IUUC-Lch-050667	Latimeria chalumnae	74.50	0.00e+00	1547.00
IUUC-Loc-052404	Lepisosteus oculatus	69.74	0.00e+00	1331.00
IUUC-Laf-053618	Loxodonta africana	92.81	0.00e+00	1793.00
IUUC-Mcc-054692	Macaca mulatta	92.33	0.00e+00	1891.00
IUUC-Meu-056025	Macropus eugenii	96.22	0.00e+00	1080.00
IUUC-Mmr-061188	Microcebus murinus	92.42	0.00e+00	1846.00
IUUC-Mmu-064146	Mus musculus	89.06	0.00e+00	1825.00
IUUC-Mpu-066217	Mustela putorius furo	91.27	0.00e+00	1825.00
IUUC-Mlu-068023	Myotis lucifugus	90.92	0.00e+00	1832.00
IUUC-Nle-069506	Nomascus leucogenys	92.42	0.00e+00	1893.00
IUUC-Opr-070587	Ochotona princeps	78.89	0.00e+00	1491.00
IUUC-Oan-073500	Ornithorhynchus anatinus	91.43	0.00e+00	1939.00
IUUC-Ocu-074299	Oryctolagus cuniculus	91.41	0.00e+00	1738.00
IUUC-Ola-086665	Oryzias latipes	78.66	0.00e+00	909.00
IUUC-Oga-088519	Otolemur garnettii	85.39	0.00e+00	1646.00
IUUC-Oar-089246	Ovis aries	91.59	0.00e+00	1739.00
IUUC-Ptr-091102	Pan troglodytes	92.33	0.00e+00	1888.00
IUUC-Pan-091952	Papio anubis	92.25	0.00e+00	1889.00
IUUC-Pfo-097227	Poecilia formosa	62.01	0.00e+00	1167.00
IUUC-Pab-097975	Pongo abelii	89.51	0.00e+00	1803.00
IUUC-Pca-101127	Procavia capensis	86.07	0.00e+00	1206.00
IUUC-Pva-102431	Pteropus vampyrus	83.51	0.00e+00	1629.00
IUUC-Sha-106690	Sarcophilus harrisii	97.71	0.00e+00	2030.00
IUUC-Ssc-116189	Sus scrofa	92.25	0.00e+00	1797.00
IUUC-Tgu-116527	Taeniopygia guttata	85.95	0.00e+00	1809.00
IUUC-Tru-118389	Takifugu rubripes	62.26	0.00e+00	1212.00
IUUC-Tsy-119193	Tarsius syrichta	89.51	0.00e+00	1780.00
IUUC-Tni-119790	Tetraodon nigroviridis	79.01	0.00e+00	872.00
IUUC-Tbe-127445	Tupaia belangeri	93.73	0.00e+00	1248.00
IUUC-Ttr-128877	Tursiops truncatus	91.63	0.00e+00	1789.00
IUUC-Xtr-132274	Xenopus tropicalis	77.98	0.00e+00	1580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence