iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000012075.1	ENSPSIT00000013757.1	ENSPSIP00000013693.1
ENSPSIG00000012075.1	ENSPSIT00000013784.1	ENSPSIP00000013720.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.00e-12	44.8	791	825

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           H  ++ cla sd  llvs++  g+i+vWD  tg++l
   Q: 791  HLMDIECLA-SDgMLLVSCCLVGQIRVWDAQTGDCL 825
           556677776.686889*****************996 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MTLTEKLRET ISRAFYNHGL LCASYPIPII LFTGLCILAC CYPLLKLPLP GTGPVEYSTP 60
VKDYSPPSSE QGPQQGDPNE RPDWYLGAPV AYIQQILVKA TVSPWRKNFL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGTTAAAA TACCAAGGAG CTTCCTCTTT GCACGTGTCT TACCTCTTTA TAAAGAGTCC 60
TTTGAGAAAG CACTGACTTC CATAGCAACA CATGAATACA ATAAGATCAG GATTACCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	81.06	0.00e+00	960.00
IUUC-Apl-003294	Anas platyrhynchos	83.99	0.00e+00	1825.00
IUUC-Aca-004424	Anolis carolinensis	71.65	0.00e+00	1516.00
IUUC-Bta-013478	Bos taurus	71.21	0.00e+00	1501.00
IUUC-Cel-018160	Caenorhabditis elegans	29.38	1.00e-65	244.00
IUUC-Cja-019123	Callithrix jacchus	69.68	0.00e+00	1451.00
IUUC-Cfa-021082	Canis familiaris	71.37	0.00e+00	1478.00
IUUC-Cpo-022477	Cavia porcellus	69.24	0.00e+00	1425.00
IUUC-Csa-023176	Chlorocebus sabaeus	69.17	0.00e+00	1405.00
IUUC-Cin-025490	Ciona intestinalis	37.24	4.00e-90	325.00
IUUC-Csv-026115	Ciona savignyi	38.17	1.00e-138	488.00
IUUC-Dre-028008	Danio rerio	64.52	0.00e+00	1364.00
IUUC-Dno-028887	Dasypus novemcinctus	76.79	0.00e+00	1036.00
IUUC-Dor-030467	Dipodomys ordii	85.41	0.00e+00	815.00
IUUC-Dme-032087	Drosophila melanogaster	32.59	3.00e-112	399.00
IUUC-Ete-032372	Echinops telfairi	56.14	0.00e+00	735.00
IUUC-Eca-033896	Equus caballus	72.15	0.00e+00	1578.00
IUUC-Eeu-035099	Erinaceus europaeus	71.09	0.00e+00	1004.00
IUUC-Fca-035616	Felis catus	81.04	0.00e+00	978.00
IUUC-Fal-037231	Ficedula albicollis	79.32	0.00e+00	1698.00
IUUC-Gmo-039439	Gadus morhua	75.05	0.00e+00	698.00
IUUC-Gac-041516	Gasterosteus aculeatus	63.76	0.00e+00	1337.00
IUUC-Hsa-046674	Homo sapiens	71.79	0.00e+00	1533.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	72.23	0.00e+00	1546.00
IUUC-Lch-049689	Latimeria chalumnae	70.88	0.00e+00	1574.00
IUUC-Loc-052417	Lepisosteus oculatus	52.50	2.00e-149	522.00
IUUC-Laf-053795	Loxodonta africana	70.76	0.00e+00	1506.00
IUUC-Mcc-055502	Macaca mulatta	72.17	0.00e+00	1527.00
IUUC-Mga-059805	Meleagris gallopavo	83.74	0.00e+00	1815.00
IUUC-Mmr-060997	Microcebus murinus	71.59	0.00e+00	1544.00
IUUC-Mdo-062940	Monodelphis domestica	74.94	0.00e+00	1543.00
IUUC-Mmu-063255	Mus musculus	71.18	0.00e+00	1525.00
IUUC-Mpu-066158	Mustela putorius furo	72.06	0.00e+00	1535.00
IUUC-Mlu-067201	Myotis lucifugus	69.09	0.00e+00	1461.00
IUUC-Nle-069145	Nomascus leucogenys	78.10	0.00e+00	1126.00
IUUC-Opr-070797	Ochotona princeps	66.72	0.00e+00	1374.00
IUUC-Ont-071553	Oreochromis niloticus	64.40	0.00e+00	1350.00
IUUC-Ocu-074598	Oryctolagus cuniculus	71.52	0.00e+00	1488.00
IUUC-Ola-086650	Oryzias latipes	65.94	3.00e-46	177.00
IUUC-Oar-089287	Ovis aries	71.78	0.00e+00	940.00
IUUC-Pan-092004	Papio anubis	72.42	0.00e+00	1538.00
IUUC-Pma-094145	Petromyzon marinus	48.96	0.00e+00	1013.00
IUUC-Pfo-096320	Poecilia formosa	63.91	0.00e+00	1345.00
IUUC-Pab-097862	Pongo abelii	72.03	0.00e+00	1540.00
IUUC-Pca-100862	Procavia capensis	61.91	0.00e+00	1262.00
IUUC-Pva-103050	Pteropus vampyrus	76.02	0.00e+00	1108.00
IUUC-Ptt-103858	Puccinia triticina	25.35	2.00e-08	54.30
IUUC-Rno-105852	Rattus norvegicus	71.42	0.00e+00	1535.00
IUUC-Sha-107312	Sarcophilus harrisii	74.21	0.00e+00	1552.00
IUUC-Sar-113311	Sorex araneus	58.31	1.00e-123	437.00
IUUC-Ssc-116356	Sus scrofa	71.95	0.00e+00	1548.00
IUUC-Tgu-116896	Taeniopygia guttata	67.32	0.00e+00	692.00
IUUC-Tru-118197	Takifugu rubripes	63.78	0.00e+00	1323.00
IUUC-Tni-119823	Tetraodon nigroviridis	60.85	0.00e+00	1296.00
IUUC-Ttr-129164	Tursiops truncatus	71.84	0.00e+00	1506.00
IUUC-Xtr-132819	Xenopus tropicalis	70.97	0.00e+00	1567.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence