iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118547

UUCD1 version

UUC-TaR-01060

Ensembl Protein ID

ENSTRUP00000010953.1

UniProt Accession

H2SEX2; H2SEX2_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004605.1	ENSTRUT00000011012.1	ENSTRUP00000010953.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.60e-31	109.5	2	113

Active Site

Position(s)	Description	Evidence
75	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 9    lekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.......... 87
           l+ +ppegi a+ +  +   + ++ + Gp+dt++egg+F + ++fp+dYP++PPk++f+ ++fhPn+y++G+vC+sil+          
   Q: 2    LTLNPPEGILAGEHPPRSKPTCSLCLRGPQDTCFEGGIFPAVLSFPSDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHapgddpmgye 90
           677899999999999988999999******************************************************88999999999 PP
   S: 88   .eeekWspalsvesvllsiqsll 109
            ++e+Wsp++sve++lls++s+l
   Q: 91   sSAERWSPVQSVEKILLSVVSML 113
           99********************9 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

ELTLNPPEGI LAGEHPPRSK PTCSLCLRGP QDTCFEGGIF PAVLSFPSDY PLSPPKMRFT 60
CEMFHPNIYP DGRVCISILH APGDDPMGYE SSAERWSPVQ SVEKILLSVV SMLA 114

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTGACCC TGAATCCACC TGAGGGGATT CTCGCAGGTG AGCATCTTTA GTTAAACAGG 60
ACTAAACTGC ACTTTCACCA ACCTCCCTTT AATGTCTTTA ATGTAAAGTG GAAGAGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002172	Ailuropoda melanoleuca	81.58	1.00e-50	191.00
IUUC-Apl-003761	Anas platyrhynchos	81.58	8.00e-51	192.00
IUUC-Aca-005062	Anolis carolinensis	79.82	1.00e-48	185.00
IUUC-Ame-011698	Astyanax mexicanus	81.58	2.00e-51	194.00
IUUC-Bta-013277	Bos taurus	94.19	3.00e-45	173.00
IUUC-Cja-019767	Callithrix jacchus	81.58	6.00e-51	192.00
IUUC-Cfa-020047	Canis familiaris	81.58	2.00e-50	191.00
IUUC-Cpo-021507	Cavia porcellus	80.70	1.00e-50	191.00
IUUC-Csa-023745	Chlorocebus sabaeus	81.58	9.00e-51	192.00
IUUC-Dre-027900	Danio rerio	80.70	2.00e-51	194.00
IUUC-Dno-029688	Dasypus novemcinctus	81.58	1.00e-50	191.00
IUUC-Ete-033010	Echinops telfairi	81.58	1.00e-49	188.00
IUUC-Eca-033294	Equus caballus	82.46	6.00e-51	192.00
IUUC-Eeu-034947	Erinaceus europaeus	68.89	5.00e-28	116.00
IUUC-Fca-036442	Felis catus	92.05	3.00e-45	173.00
IUUC-Fal-037188	Ficedula albicollis	81.58	2.00e-50	191.00
IUUC-Gmo-038663	Gadus morhua	81.58	2.00e-51	194.00
IUUC-Gga-040355	Gallus gallus	80.70	1.00e-50	192.00
IUUC-Gac-041847	Gasterosteus aculeatus	83.33	2.00e-52	198.00
IUUC-Ggo-045202	Gorilla gorilla	80.70	1.00e-50	191.00
IUUC-Hsa-046369	Homo sapiens	80.70	1.00e-50	191.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	80.70	2.00e-50	191.00
IUUC-Lch-049596	Latimeria chalumnae	81.58	4.00e-51	193.00
IUUC-Loc-052346	Lepisosteus oculatus	96.51	1.00e-46	177.00
IUUC-Laf-054560	Loxodonta africana	81.58	7.00e-51	192.00
IUUC-Mcc-055172	Macaca mulatta	80.70	1.00e-50	191.00
IUUC-Meu-056891	Macropus eugenii	81.58	8.00e-51	192.00
IUUC-Mga-059939	Meleagris gallopavo	81.58	1.00e-50	191.00
IUUC-Mmr-061029	Microcebus murinus	92.05	2.00e-45	174.00
IUUC-Mdo-061820	Monodelphis domestica	80.70	1.00e-50	191.00
IUUC-Mmu-063123	Mus musculus	80.70	1.00e-50	191.00
IUUC-Mpu-065866	Mustela putorius furo	81.58	2.00e-50	191.00
IUUC-Mlu-067220	Myotis lucifugus	81.58	1.00e-50	192.00
IUUC-Nle-070007	Nomascus leucogenys	80.70	1.00e-50	191.00
IUUC-Opr-071095	Ochotona princeps	81.42	1.00e-49	187.00
IUUC-Ont-071736	Oreochromis niloticus	82.46	3.00e-52	197.00
IUUC-Oan-073475	Ornithorhynchus anatinus	81.58	1.00e-50	191.00
IUUC-Ocu-074820	Oryctolagus cuniculus	81.58	2.00e-50	191.00
IUUC-Ola-087571	Oryzias latipes	82.46	5.00e-52	196.00
IUUC-Oar-089706	Ovis aries	80.70	1.00e-50	191.00
IUUC-Ptr-090798	Pan troglodytes	80.70	1.00e-50	191.00
IUUC-Pan-091967	Papio anubis	80.70	1.00e-50	191.00
IUUC-Psi-093524	Pelodiscus sinensis	81.58	2.00e-50	191.00
IUUC-Pfo-097330	Poecilia formosa	82.46	4.00e-52	196.00
IUUC-Pab-098225	Pongo abelii	80.53	4.00e-50	189.00
IUUC-Pca-101040	Procavia capensis	81.58	1.00e-50	191.00
IUUC-Pva-102507	Pteropus vampyrus	81.58	1.00e-50	192.00
IUUC-Rno-105228	Rattus norvegicus	80.70	1.00e-50	191.00
IUUC-Sha-107274	Sarcophilus harrisii	81.58	1.00e-50	192.00
IUUC-Ssc-115365	Sus scrofa	82.46	1.00e-50	192.00
IUUC-Tgu-116816	Taeniopygia guttata	80.70	1.00e-50	192.00
IUUC-Tni-120278	Tetraodon nigroviridis	85.22	3.00e-53	200.00
IUUC-Tbe-127792	Tupaia belangeri	80.70	1.00e-50	191.00
IUUC-Ttr-128619	Tursiops truncatus	81.58	2.00e-50	190.00
IUUC-Xtr-132450	Xenopus tropicalis	80.70	4.00e-50	190.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence