iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068034

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02003622

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017407.2	ENSMLUT00000017413.2	ENSMLUP00000015877.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-78	264.6	42	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp....kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++    + +   +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEEkdnpDAKVRIIPLQLQRLFAQLLLLDQEAASTADLTDSFGWTSNE--E 128
           9*****************************777766554431111334448899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+++e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNVSEKQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKNVT-----GLEDALwNMYVEEEVFDCDNLYHCGSCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 275
           *****.....9****************************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc++++ ++  ++ Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQSQLDDL-EYMYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqlqeekskpdvnlkdlqneeeiddplmilkailsqeesnlilvd 363
           ****999987.9***************************************************************************** PP
   S: 302  .................................................................................ekgkWllf 309
                                                                                            +  +W+ +
   Q: 364  llgqkllkkigiswnkkyrkqygplrkflqlhsqifllssdestvsllknsslqaesdfqrkdqqifktltsespglndrtSCSHWFDI 452
           **********************************************************999999999999998888865543444**** PP
   S: 310  dDskVtevkeeevleetg..staYvlfYkr 337
           +DskV++++e++++++ +  ++aY+lfY++
   Q: 453  NDSKVQPIEEKDIKQQFQgkESAYMLFYRK 482
           ***************8889*********98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MFGDLFEEDY SSVSNNQYGK GKKLKAKPLE PPAPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGSL EEKDNPDAKV RIIPLQLQRL FAQLLLLDQE AASTADLTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACCTATTTGA AGAGGATTAT TCCAGTGTGT CAAATAATCA GTATGGAAAA 60
GGAAAAAAAT TAAAGGCCAA ACCATTGGAG CCACCTGCTC CTAGAGAGTT TACCAATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	85.30	0.00e+00	1967.00
IUUC-Apl-004105	Anas platyrhynchos	63.09	0.00e+00	1535.00
IUUC-Aca-004715	Anolis carolinensis	61.88	0.00e+00	1474.00
IUUC-Ame-011073	Astyanax mexicanus	46.88	0.00e+00	1025.00
IUUC-Bta-012487	Bos taurus	86.50	0.00e+00	2074.00
IUUC-Cja-018937	Callithrix jacchus	83.76	0.00e+00	2043.00
IUUC-Cfa-020645	Canis familiaris	81.00	0.00e+00	1274.00
IUUC-Cpo-022160	Cavia porcellus	78.59	0.00e+00	1925.00
IUUC-Csa-023078	Chlorocebus sabaeus	83.75	0.00e+00	2090.00
IUUC-Cho-025013	Choloepus hoffmanni	66.14	0.00e+00	813.00
IUUC-Csv-026193	Ciona savignyi	54.17	1.00e-58	219.00
IUUC-Dre-027416	Danio rerio	48.26	0.00e+00	1137.00
IUUC-Dno-029639	Dasypus novemcinctus	80.82	0.00e+00	1672.00
IUUC-Dor-030624	Dipodomys ordii	90.37	7.00e-153	535.00
IUUC-Ete-032626	Echinops telfairi	65.42	0.00e+00	768.00
IUUC-Eca-034208	Equus caballus	86.50	0.00e+00	2126.00
IUUC-Eeu-035340	Erinaceus europaeus	47.73	5.00e-96	346.00
IUUC-Fca-035886	Felis catus	76.64	0.00e+00	797.00
IUUC-Fal-036925	Ficedula albicollis	63.42	0.00e+00	1459.00
IUUC-Gmo-038597	Gadus morhua	45.52	0.00e+00	912.00
IUUC-Gga-041171	Gallus gallus	62.53	0.00e+00	1506.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.48	0.00e+00	979.00
IUUC-Ggo-045069	Gorilla gorilla	82.59	0.00e+00	1879.00
IUUC-Hsa-046715	Homo sapiens	84.80	0.00e+00	2082.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	79.92	0.00e+00	1921.00
IUUC-Lch-050182	Latimeria chalumnae	51.87	0.00e+00	1155.00
IUUC-Loc-052705	Lepisosteus oculatus	53.88	0.00e+00	1265.00
IUUC-Laf-054132	Loxodonta africana	82.05	0.00e+00	2038.00
IUUC-Mcc-055734	Macaca mulatta	84.07	0.00e+00	2092.00
IUUC-Meu-056135	Macropus eugenii	84.55	4.00e-113	402.00
IUUC-Mga-060092	Meleagris gallopavo	62.48	0.00e+00	1490.00
IUUC-Mmr-061546	Microcebus murinus	80.63	0.00e+00	1952.00
IUUC-Mdo-061935	Monodelphis domestica	62.85	0.00e+00	1521.00
IUUC-Mmu-063630	Mus musculus	78.33	0.00e+00	1934.00
IUUC-Mpu-066579	Mustela putorius furo	81.58	0.00e+00	2023.00
IUUC-Nle-069082	Nomascus leucogenys	81.90	0.00e+00	1709.00
IUUC-Opr-070953	Ochotona princeps	69.82	0.00e+00	950.00
IUUC-Ont-072435	Oreochromis niloticus	46.47	0.00e+00	1103.00
IUUC-Oan-073339	Ornithorhynchus anatinus	66.38	0.00e+00	1565.00
IUUC-Ocu-073760	Oryctolagus cuniculus	80.44	0.00e+00	1975.00
IUUC-Ola-087015	Oryzias latipes	46.27	0.00e+00	934.00
IUUC-Oga-088960	Otolemur garnettii	83.51	0.00e+00	2051.00
IUUC-Oar-089853	Ovis aries	86.36	0.00e+00	2092.00
IUUC-Ptr-091093	Pan troglodytes	84.40	0.00e+00	2073.00
IUUC-Pan-091962	Papio anubis	83.04	0.00e+00	2066.00
IUUC-Psi-093691	Pelodiscus sinensis	65.89	0.00e+00	1607.00
IUUC-Pma-094428	Petromyzon marinus	65.11	3.00e-92	331.00
IUUC-Pfo-096983	Poecilia formosa	47.31	0.00e+00	1027.00
IUUC-Pab-097860	Pongo abelii	83.30	0.00e+00	1909.00
IUUC-Pca-100514	Procavia capensis	78.20	0.00e+00	649.00
IUUC-Pva-102771	Pteropus vampyrus	85.45	0.00e+00	1957.00
IUUC-Rno-105405	Rattus norvegicus	77.53	0.00e+00	1886.00
IUUC-Sha-107376	Sarcophilus harrisii	63.94	0.00e+00	1483.00
IUUC-Ssc-115819	Sus scrofa	81.49	0.00e+00	1439.00
IUUC-Tgu-117262	Taeniopygia guttata	62.06	0.00e+00	1504.00
IUUC-Tru-117601	Takifugu rubripes	46.71	0.00e+00	1086.00
IUUC-Tsy-118996	Tarsius syrichta	72.37	0.00e+00	1579.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.03	0.00e+00	870.00
IUUC-Tbe-127616	Tupaia belangeri	64.89	0.00e+00	1117.00
IUUC-Ttr-129075	Tursiops truncatus	84.26	0.00e+00	1933.00
IUUC-Vpa-130108	Vicugna pacos	86.47	0.00e+00	1875.00
IUUC-Xtr-132623	Xenopus tropicalis	52.04	0.00e+00	1198.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence