iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073315

Ensembl Protein ID

ENSOANP00000006413.3

UniProt Accession

F6UVV8; F6UVV8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

EML1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004045.3	ENSOANT00000006415.3	ENSOANP00000006413.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.60e-18	64.3	526	559
UBD/Beta-Prp	2.30e-40	138.9	517	684

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gHtd+ ++la  s+   ++++++D+ + +WD ++
   Q: 526  GHTDELWGLAIhSSkAQFLTCGHDKHVTLWDASS 559
           8**********966688**************665 PP

UBD/Beta-Prp

   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           tg+   + +gh+d+++ l+++ s+  +++ +hd+ + +wd ++   +   +++ ++  +   +hp+g++++ G+l +   ++d +t++l
   Q: 517  TGDFYPITQGHTDELWGLAIHSSKAQFLTCGHDKHVTLWDASSHCPI--WNKIIEDPAQASGFHPSGSVVAVGTLTGRWFVFDTETKDL 603
           56667788999999999999999999999999999999999988888..6999999999999999999999999999999999999999 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           ++  t   +++   + ++++g++l+ gs+d+ + ++ +     + + + ++ gh+++++ ++ s n+++lvs s D  i  W
   Q: 604  VTVHTD-GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVNdngrKYSRIGKCSGHSSFITHLDWSVNSQYLVSNSGDYEILYW 684
           999987.889999999999999999999999999999998655555599999999999999999999999999999888888 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MEVTDRIASL EQRVQMQEDD IQLLKSALAD VVRRLNITEE QQAMLNRKGP TKARPLVQTL 60
PLRTTVNNGT VLPKKPSGSL PSPSGARKET ISPATKRSVN LLSACKLNKS APSTIKRTSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAGCTGTC CTATTTATAA CCTTTAGTTT CTTATTCTCT ATTTTAGATG ACAGTGCTTC 60
AGCAGCAAGT AGCATGGAGG TAACTGATCG CATCGCGTCT CTGGAGCAAC GGGTCCAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0015630--C:microtubule cytoskeleton
GO:1990023--C:mitotic spindle midzone
GO:0097431--C:mitotic spindle pole
GO:0008017--F:microtubule binding
GO:0007420--P:brain development
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0007052--P:mitotic spindle organization
GO:0007405--P:neuroblast proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002077	Ailuropoda melanoleuca	91.84	0.00e+00	1457.00
IUUC-Apl-004179	Anas platyrhynchos	93.00	0.00e+00	1467.00
IUUC-Aca-004993	Anolis carolinensis	89.43	0.00e+00	1407.00
IUUC-Ame-011332	Astyanax mexicanus	77.00	0.00e+00	1287.00
IUUC-Bta-013419	Bos taurus	78.47	0.00e+00	1228.00
IUUC-Cel-018623	Caenorhabditis elegans	29.62	2.00e-81	296.00
IUUC-Cja-018976	Callithrix jacchus	93.03	0.00e+00	1484.00
IUUC-Cfa-021276	Canis familiaris	91.77	0.00e+00	1447.00
IUUC-Csa-023355	Chlorocebus sabaeus	93.03	0.00e+00	1481.00
IUUC-Cin-025784	Ciona intestinalis	55.54	0.00e+00	750.00
IUUC-Csv-026305	Ciona savignyi	48.50	0.00e+00	755.00
IUUC-Dre-028728	Danio rerio	76.64	0.00e+00	1270.00
IUUC-Dno-029055	Dasypus novemcinctus	92.66	0.00e+00	1491.00
IUUC-Dor-030628	Dipodomys ordii	92.03	0.00e+00	1438.00
IUUC-Dme-032093	Drosophila melanogaster	38.00	5.00e-121	428.00
IUUC-Ete-032845	Echinops telfairi	91.79	0.00e+00	792.00
IUUC-Eca-034266	Equus caballus	91.64	0.00e+00	1496.00
IUUC-Eeu-035302	Erinaceus europaeus	63.76	2.00e-151	528.00
IUUC-Fca-035446	Felis catus	91.00	0.00e+00	1443.00
IUUC-Fal-036734	Ficedula albicollis	93.41	0.00e+00	1482.00
IUUC-Gmo-038689	Gadus morhua	73.61	0.00e+00	1239.00
IUUC-Gga-040934	Gallus gallus	94.87	0.00e+00	1149.00
IUUC-Gac-042476	Gasterosteus aculeatus	75.12	0.00e+00	1249.00
IUUC-Ggo-044828	Gorilla gorilla	92.78	0.00e+00	1518.00
IUUC-Hsa-045664	Homo sapiens	92.90	0.00e+00	1521.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	59.56	0.00e+00	967.00
IUUC-Lch-050508	Latimeria chalumnae	82.91	0.00e+00	1375.00
IUUC-Loc-052823	Lepisosteus oculatus	81.11	0.00e+00	1346.00
IUUC-Laf-054164	Loxodonta africana	87.73	0.00e+00	1360.00
IUUC-Mcc-055810	Macaca mulatta	90.75	0.00e+00	1466.00
IUUC-Meu-056664	Macropus eugenii	65.11	0.00e+00	922.00
IUUC-Mga-059405	Meleagris gallopavo	89.56	0.00e+00	1438.00
IUUC-Mmr-061144	Microcebus murinus	91.22	0.00e+00	1448.00
IUUC-Mdo-062834	Monodelphis domestica	90.73	0.00e+00	1468.00
IUUC-Mmu-063955	Mus musculus	90.62	0.00e+00	1429.00
IUUC-Mpu-066240	Mustela putorius furo	91.50	0.00e+00	1423.00
IUUC-Mlu-067847	Myotis lucifugus	90.98	0.00e+00	1066.00
IUUC-Nle-069783	Nomascus leucogenys	91.52	0.00e+00	1472.00
IUUC-Opr-070409	Ochotona princeps	84.62	0.00e+00	1313.00
IUUC-Ont-072468	Oreochromis niloticus	75.96	0.00e+00	1258.00
IUUC-Ocu-074604	Oryctolagus cuniculus	89.02	0.00e+00	1194.00
IUUC-Ola-086734	Oryzias latipes	74.19	0.00e+00	1231.00
IUUC-Oga-089105	Otolemur garnettii	93.15	0.00e+00	1461.00
IUUC-Oar-090057	Ovis aries	91.36	0.00e+00	1475.00
IUUC-Ptr-091138	Pan troglodytes	92.78	0.00e+00	1518.00
IUUC-Pan-092691	Papio anubis	86.18	0.00e+00	1351.00
IUUC-Psi-093076	Pelodiscus sinensis	93.42	0.00e+00	1487.00
IUUC-Pma-094555	Petromyzon marinus	56.61	0.00e+00	821.00
IUUC-Pfo-096794	Poecilia formosa	75.37	0.00e+00	1238.00
IUUC-Pab-097787	Pongo abelii	90.63	0.00e+00	1506.00
IUUC-Pca-101070	Procavia capensis	59.97	0.00e+00	816.00
IUUC-Pva-102676	Pteropus vampyrus	90.67	0.00e+00	1424.00
IUUC-Rno-105971	Rattus norvegicus	81.05	0.00e+00	1236.00
IUUC-Sha-107530	Sarcophilus harrisii	93.76	0.00e+00	1473.00
IUUC-Ssc-116169	Sus scrofa	77.84	0.00e+00	1012.00
IUUC-Tgu-117046	Taeniopygia guttata	92.38	0.00e+00	1454.00
IUUC-Tru-118596	Takifugu rubripes	72.10	0.00e+00	1215.00
IUUC-Tsy-119142	Tarsius syrichta	89.90	0.00e+00	1068.00
IUUC-Tni-120377	Tetraodon nigroviridis	74.69	0.00e+00	1239.00
IUUC-Tbe-127916	Tupaia belangeri	75.04	0.00e+00	960.00
IUUC-Ttr-129042	Tursiops truncatus	92.41	0.00e+00	1514.00
IUUC-Xtr-132117	Xenopus tropicalis	83.44	0.00e+00	1338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence