iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017252

Ensembl Protein ID

Bra018338.1-P

UniProt Accession

M4DP97; M4DP97_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra018338	Bra018338.1	Bra018338.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	8.80e-169	563.1	497	984

Active Site

Position(s)	Description	Evidence
678	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnve 91
           YD Qi ++G++ q+kl+ akv+ vG g+lGcE+lKn++l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np+ n+e
   Q: 497  YDAQISVFGAKFQQKLEDAKVFTVGSGALGCEFLKNMALMGVscgdqGKLTVTDDDIIEKSNLSRQFLFRDWNIGQAKSTVAASAAAAINPKFNIE 592
           ************************************************************************************************ PP
   S: 92   aheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaae 184
           a ++++ +++e+++   F ++++vVv+aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++
   Q: 593  ALQNRVGAETENVFddaFWENLTVVVNALDNVNARLYVDSRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNID 688
           ************99********************************************************************************** PP
   S: 185  htiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtks 268
           h+++wa            + +n +l+   + ++       ++ +++++++ + l +e+ enf+++ ++a+  f+ ++ n +kql+  f+ d  t+ 
   Q: 689  HCLTWArsefegllektpAEVNAYLSSPVEYTNSMMSAGDAQARDTLERIVECLDKEKCENFQDCLTWARLRFEDYFVNRVKQLIYTFPEDAATST 784
           ***********999999977777777777777777777888999999999999999**************************************** PP
   S: 269  kspfwv.........................................................sfcsnaealqvpekvekdeevvkasap..lyll 305
           ++pfw+                                                          f++ ++a+ v +  +   ++ +++++  +  l
   Q: 785  GAPFWSapkrfprplqysssdpsllnfitatailraetfgipvpewtkdpkaaaeaidnvivpDFEPRKDAKIVTDEKATTLTTASVDDAavINDL 880
           ****************************************************99999999999888888777766666666666666666686666 PP
   S: 306  lralerfek..kkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfepl 395
           +++le+ ++   ++  ++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv++g  k e++
   Q: 881  IAKLEKCRHnlSPDFRMKPIQFEKDDDTnyHMDVIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGghKVEAY 975
           6666665551168899999*******************************.***************************************9***** PP
   S: 396  knfflfdae 404
           +n+f ++a+
   Q: 976  RNTFANLAL 984
           ****99875 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MLEPPLVLIS MAFSYVFLRF LHHFMLQKRA SEASSVASEI ASSDLASSSS PIKRRRVEIT 60
DSASENSSIV AASGSSSVVQ QQRDMAFGNS NRQEIDEDLH SRQLAVYGRE TMRRLFASNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTGAAC CTCCTCTCGT TTTGATCTCT ATGGCGTTCT CTTACGTTTT CCTCAGGTTC 60
CTCCACCACT TTATGCTTCA AAAGCGAGCT AGTGAAGCCT CATCTGTTGC TAGCGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	78.91	0.00e+00	1657.00
IUUC-Aml-001311	Ailuropoda melanoleuca	43.49	0.00e+00	878.00
IUUC-Atr-002684	Amborella trichopoda	73.49	0.00e+00	1658.00
IUUC-Aly-005418	Arabidopsis lyrata	95.51	0.00e+00	2033.00
IUUC-Ath-006992	Arabidopsis thaliana	92.15	0.00e+00	1995.00
IUUC-Ago-007873	Ashbya gossypii	45.37	0.00e+00	830.00
IUUC-Acl-008181	Aspergillus clavatus	45.07	0.00e+00	820.00
IUUC-Afl-008455	Aspergillus flavus	45.00	0.00e+00	798.00
IUUC-Afu-009065	Aspergillus fumigatus	45.46	0.00e+00	841.00
IUUC-Ani-009371	Aspergillus nidulans	45.56	0.00e+00	810.00
IUUC-Aor-010007	Aspergillus oryzae	45.00	0.00e+00	797.00
IUUC-Ate-010466	Aspergillus terreus	44.69	0.00e+00	840.00
IUUC-Ame-010933	Astyanax mexicanus	43.87	0.00e+00	841.00
IUUC-Bgr-012281	Blumeria graminis	43.34	0.00e+00	815.00
IUUC-Bta-012767	Bos taurus	43.86	0.00e+00	885.00
IUUC-Bdi-014843	Brachypodium distachyon	78.47	0.00e+00	1607.00
IUUC-Bol-015880	Brassica oleracea	98.06	0.00e+00	2129.00
IUUC-Cfa-020622	Canis familiaris	42.66	0.00e+00	841.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	57.76	0.00e+00	1165.00
IUUC-Csa-023780	Chlorocebus sabaeus	43.96	0.00e+00	885.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	45.53	0.00e+00	870.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.53	0.00e+00	683.00
IUUC-Dre-028149	Danio rerio	44.53	0.00e+00	869.00
IUUC-Dno-028884	Dasypus novemcinctus	43.86	0.00e+00	882.00
IUUC-Dor-030229	Dipodomys ordii	42.09	0.00e+00	835.00
IUUC-Dse-031524	Dothistroma septosporum	42.18	0.00e+00	810.00
IUUC-Dme-032045	Drosophila melanogaster	44.00	0.00e+00	845.00
IUUC-Ete-033124	Echinops telfairi	39.79	5.00e-128	452.00
IUUC-Eca-033330	Equus caballus	43.94	0.00e+00	882.00
IUUC-Fca-036255	Felis catus	43.58	0.00e+00	876.00
IUUC-Gmo-039338	Gadus morhua	43.15	0.00e+00	831.00
IUUC-Gac-041773	Gasterosteus aculeatus	43.55	0.00e+00	847.00
IUUC-Gma-043165	Glycine max	84.49	0.00e+00	1828.00
IUUC-Ggo-045336	Gorilla gorilla	43.86	0.00e+00	867.00
IUUC-Hsa-045982	Homo sapiens	43.86	0.00e+00	867.00
IUUC-Hvu-047418	Hordeum vulgare	78.71	0.00e+00	1625.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	44.24	0.00e+00	892.00
IUUC-Lch-050371	Latimeria chalumnae	43.87	0.00e+00	877.00
IUUC-Lpe-051299	Leersia perrieri	75.07	0.00e+00	1607.00
IUUC-Loc-052936	Lepisosteus oculatus	44.12	0.00e+00	877.00
IUUC-Laf-053948	Loxodonta africana	43.58	0.00e+00	861.00
IUUC-Mcc-055843	Macaca mulatta	43.86	0.00e+00	884.00
IUUC-Mtr-058572	Medicago truncatula	80.05	0.00e+00	1745.00
IUUC-Mvi-060437	Microbotryum violaceum	42.94	0.00e+00	821.00
IUUC-Mmr-061405	Microcebus murinus	43.41	0.00e+00	852.00
IUUC-Mac-065505	Musa acuminata	76.91	0.00e+00	1651.00
IUUC-Mpu-066409	Mustela putorius furo	43.86	0.00e+00	891.00
IUUC-Mlu-067217	Myotis lucifugus	43.77	0.00e+00	877.00
IUUC-Nfi-068407	Neosartorya fischeri	45.38	0.00e+00	823.00
IUUC-Opr-070715	Ochotona princeps	35.07	2.00e-149	523.00
IUUC-Ont-071671	Oreochromis niloticus	44.33	0.00e+00	866.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.09	0.00e+00	630.00
IUUC-Ocu-074544	Oryctolagus cuniculus	44.05	0.00e+00	890.00
IUUC-Oba-075120	Oryza barthii	79.29	0.00e+00	1625.00
IUUC-Obr-076557	Oryza brachyantha	77.35	0.00e+00	1637.00
IUUC-Ogl-077887	Oryza glaberrima	79.29	0.00e+00	1626.00
IUUC-Ogu-078305	Oryza glumaepatula	75.32	0.00e+00	1602.00
IUUC-Oin-079370	Oryza indica	77.10	0.00e+00	1602.00
IUUC-Olo-081089	Oryza longistaminata	75.42	0.00e+00	1605.00
IUUC-Ome-081942	Oryza meridionalis	79.78	0.00e+00	1636.00
IUUC-Oni-082365	Oryza nivara	79.68	0.00e+00	1632.00
IUUC-Opu-083301	Oryza punctata	79.58	0.00e+00	1634.00
IUUC-Oru-084469	Oryza rufipogon	75.52	0.00e+00	1606.00
IUUC-Osa-085949	Oryza sativa	79.39	0.00e+00	1648.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.72	0.00e+00	1144.00
IUUC-Oga-088594	Otolemur garnettii	43.79	0.00e+00	866.00
IUUC-Oar-090068	Ovis aries	43.88	0.00e+00	881.00
IUUC-Pan-092114	Papio anubis	43.86	0.00e+00	884.00
IUUC-Ppa-095227	Physcomitrella patens	70.40	0.00e+00	1521.00
IUUC-Pfo-097184	Poecilia formosa	44.23	0.00e+00	863.00
IUUC-Pab-097861	Pongo abelii	43.67	0.00e+00	852.00
IUUC-Pop-098934	Populus trichocarpa	78.43	0.00e+00	1763.00
IUUC-Ppe-102012	Prunus persica	80.55	0.00e+00	1759.00
IUUC-Pva-102584	Pteropus vampyrus	44.05	0.00e+00	914.00
IUUC-Rno-105462	Rattus norvegicus	43.58	0.00e+00	862.00
IUUC-Spo-108034	Schizosaccharomyces pombe	44.10	0.00e+00	835.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	45.71	0.00e+00	812.00
IUUC-Smo-109211	Selaginella moellendorffii	71.13	0.00e+00	1548.00
IUUC-Sit-110281	Setaria italica	79.78	0.00e+00	1652.00
IUUC-Sly-110914	Solanum lycopersicum	79.35	0.00e+00	1734.00
IUUC-Stu-112001	Solanum tuberosum	81.67	0.00e+00	1685.00
IUUC-Sar-113737	Sorex araneus	43.73	0.00e+00	878.00
IUUC-Sbi-114520	Sorghum bicolor	79.68	0.00e+00	1648.00
IUUC-Sre-115148	Sporisorium reilianum	44.97	0.00e+00	820.00
IUUC-Ssc-115777	Sus scrofa	43.94	0.00e+00	884.00
IUUC-Tca-121436	Theobroma cacao	83.38	0.00e+00	1806.00
IUUC-Tre-122009	Trichoderma reesei	47.06	0.00e+00	826.00
IUUC-Tvi-122259	Trichoderma virens	46.31	0.00e+00	816.00
IUUC-Tae-125113	Triticum aestivum	78.71	0.00e+00	1594.00
IUUC-Tur-126330	Triticum urartu	78.81	0.00e+00	1657.00
IUUC-Ttr-128331	Tursiops truncatus	43.70	0.00e+00	869.00
IUUC-Vda-129977	Verticillium dahliae	47.84	0.00e+00	811.00
IUUC-Vvi-130857	Vitis vinifera	84.46	0.00e+00	1790.00
IUUC-Xtr-132026	Xenopus tropicalis	39.17	0.00e+00	662.00
IUUC-Yli-134547	Yarrowia lipolytica	45.91	0.00e+00	866.00
IUUC-Zma-135052	Zea mays	78.66	0.00e+00	1656.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence