iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggr-039823

Ensembl Protein ID

GGTG_03734T0

UniProt Accession

J3NR29; J3NR29_GAGT3

Genbank Protein ID

EJT78635.1

Protein Name

Ubiquitin-activating enzyme E1 1

Genbank Nucleotide ID

ADBI01000313

Gene Name

GGTG_03734

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GGTG_03734	GGTG_03734T0	GGTG_03734T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.70e-185	615.9	428	913

Active Site

Position(s)	Description	Evidence
611	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn..v 90
           YD+Qi+++G e+q+k+ + k +lvGag++GcE+lKn +++G+     g+i ++Dmd +e+snlnrqFLfr++dvg+ K+++aa+a+  +np  +  +
   Q: 428  YDGQIAVFGKEYQDKVANMKQFLVGAGAIGCEMLKNWAMIGLgagpeGKIVITDMDSIEKSNLNRQFLFRPKDVGQMKSDCAAKAAELMNPELSghI 524
           ********************************************************************************************97225 PP
   S: 91   eaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaae 184
           +  ++++ +++e+i+   F   +d+V +aldn+ear++v+r+c+  ++pl+esgtlG++G+++v++++lte+ys+s+dpp++++P+ctl+++pn++e
   Q: 525  VCLKDRVGPDTEHIFneeFWGGLDGVTNALDNVEARTYVDRRCVFFHKPLLESGTLGTKGNTQVVLPKLTESYSSSQDPPEQSFPMCTLRSFPNKIE 621
           6679*********9999999999************************************************************************** PP
   S: 185  htiewa............vlfnklleeea.geeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtks 268
           hti wa            + +n +l++ +  e++ ++  ++++++e+++     l + + ++fe+++ +a++ f+k ++n i+qll++f++d v++ 
   Q: 622  HTIAWArelfdssfirpaETVNLYLSQPNyLESTLKQGGNEKQTLETLRDY---LIKDRARSFEDCVIWARNLFEKNYNNAIRQLLHNFPKDSVSST 715
           *****************9888887766550555555555555555555555...7788999************************************ PP
   S: 269  kspfwv.......................................................sfcsnaealq.vpekvekdeevvkasap........ 301
           ++pfw+                                                       +f++  + +   +ek  +         p        
   Q: 716  GTPFWSgpkrapdpltfdpedpshfgfvvaaaslhafnyninvkdktkqdflgvlsnmiieEFEPDPDVKIqADEKEPD---------Pnagasafd 803
           ********************************99999988888777777777777777777555554433312222222.........122222233 PP
   S: 302  ....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg.. 390
               l+  ++ l   +   g k + ++fekddds  ++d++taa+nlra +++ie+ +d++++k iag+iipaiatt+a v Gl+ +E++K+v+g  
   Q: 804  daneLEQITKELPAPKDMAGFKLTPVEFEKDDDSnhHIDFITAASNLRAANYKIEQ-ADRHKTKFIAGKIIPAIATTTALVTGLVILELYKIVDGkd 899
           4556****************************************************.**************************************77 PP
   S: 391  kfeplknfflfdae 404
           + e++kn f+++a+
   Q: 900  DIEQYKNGFVNLAL 913
           7889*****99875 PP

Organism

Gaeumannomyces graminis

Protein Sequence
(Fasta)

MADQRLPEVD LVTRMQVDDS VVNVVGTGEI DESLYSRQLY VLGHEAMRRM GASNVLIAGL 60
KGLGVEIAKN IALAGVKSLS LHDPAPVAIA DLSSQFFLRP EDVGKPRDQV TAPRVAELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACCACGGG CGCCTTCAAG CCACCTCATT TGCGTCTACA CACCACCTGG ACTGTGGTGA 60
AGCCTGGCGT TTCCATCACC TGCGCCGCGT CAACGAGACG ATCCCGAAGC CGAAGCCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	44.31	0.00e+00	842.00
IUUC-Aml-001311	Ailuropoda melanoleuca	54.18	0.00e+00	1090.00
IUUC-Atr-002684	Amborella trichopoda	44.88	0.00e+00	854.00
IUUC-Apl-004158	Anas platyrhynchos	44.10	0.00e+00	696.00
IUUC-Aca-004620	Anolis carolinensis	54.39	0.00e+00	1090.00
IUUC-Aly-005515	Arabidopsis lyrata	44.86	0.00e+00	856.00
IUUC-Ath-006891	Arabidopsis thaliana	45.02	0.00e+00	858.00
IUUC-Ago-007873	Ashbya gossypii	59.84	0.00e+00	1174.00
IUUC-Acl-008181	Aspergillus clavatus	69.68	0.00e+00	1473.00
IUUC-Afl-008455	Aspergillus flavus	69.46	0.00e+00	1418.00
IUUC-Afu-009065	Aspergillus fumigatus	69.91	0.00e+00	1499.00
IUUC-Ani-009371	Aspergillus nidulans	69.61	0.00e+00	1449.00
IUUC-Ang-009737	Aspergillus niger	69.78	0.00e+00	1477.00
IUUC-Aor-010007	Aspergillus oryzae	69.46	0.00e+00	1417.00
IUUC-Ate-010466	Aspergillus terreus	69.12	0.00e+00	1494.00
IUUC-Ame-010933	Astyanax mexicanus	53.60	0.00e+00	1023.00
IUUC-Bgr-012281	Blumeria graminis	70.70	0.00e+00	1516.00
IUUC-Bta-012767	Bos taurus	54.09	0.00e+00	1097.00
IUUC-Bci-013721	Botrytis cinerea	74.73	0.00e+00	1539.00
IUUC-Bdi-014009	Brachypodium distachyon	44.46	0.00e+00	847.00
IUUC-Bol-015665	Brassica oleracea	45.74	0.00e+00	857.00
IUUC-Bra-017707	Brassica rapa	45.52	0.00e+00	865.00
IUUC-Cel-018260	Caenorhabditis elegans	45.30	0.00e+00	818.00
IUUC-Cja-019152	Callithrix jacchus	54.43	0.00e+00	1092.00
IUUC-Cfa-020622	Canis familiaris	53.37	0.00e+00	1040.00
IUUC-Cpo-022526	Cavia porcellus	54.47	0.00e+00	1075.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.24	0.00e+00	784.00
IUUC-Csa-023780	Chlorocebus sabaeus	54.05	0.00e+00	1082.00
IUUC-Cho-024682	Choloepus hoffmanni	40.33	5.00e-96	344.00
IUUC-Cin-025790	Ciona intestinalis	50.33	0.00e+00	1041.00
IUUC-Csv-026084	Ciona savignyi	50.28	0.00e+00	1032.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	76.26	0.00e+00	1669.00
IUUC-Cne-026960	Cryptococcus neoformans	60.08	0.00e+00	1201.00
IUUC-Cme-027290	Cyanidioschyzon merolae	43.49	0.00e+00	798.00
IUUC-Dre-028149	Danio rerio	54.13	0.00e+00	1063.00
IUUC-Dno-028884	Dasypus novemcinctus	54.58	0.00e+00	1095.00
IUUC-Dor-030229	Dipodomys ordii	52.29	0.00e+00	1022.00
IUUC-Dse-031524	Dothistroma septosporum	70.01	0.00e+00	1442.00
IUUC-Dme-032045	Drosophila melanogaster	51.03	0.00e+00	1004.00
IUUC-Ete-033124	Echinops telfairi	43.30	5.00e-152	530.00
IUUC-Eca-033330	Equus caballus	54.24	0.00e+00	1091.00
IUUC-Eeu-035323	Erinaceus europaeus	42.46	2.00e-150	525.00
IUUC-Fca-036255	Felis catus	54.54	0.00e+00	1090.00
IUUC-Fal-036848	Ficedula albicollis	44.21	0.00e+00	715.00
IUUC-Fox-038007	Fusarium oxysporum	72.63	0.00e+00	833.00
IUUC-Fso-038339	Fusarium solani	75.22	0.00e+00	1583.00
IUUC-Gmo-039338	Gadus morhua	52.67	0.00e+00	1020.00
IUUC-Gga-040747	Gallus gallus	43.37	0.00e+00	685.00
IUUC-Gac-041773	Gasterosteus aculeatus	51.85	0.00e+00	1014.00
IUUC-Gma-043198	Glycine max	44.74	0.00e+00	854.00
IUUC-Ggo-045336	Gorilla gorilla	54.24	0.00e+00	1071.00
IUUC-Hsa-045982	Homo sapiens	54.24	0.00e+00	1071.00
IUUC-Hvu-047418	Hordeum vulgare	45.39	0.00e+00	843.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.54	0.00e+00	1094.00
IUUC-Kpa-049112	Komagataella pastoris	59.77	0.00e+00	1162.00
IUUC-Lch-050371	Latimeria chalumnae	54.78	0.00e+00	1090.00
IUUC-Lpe-051299	Leersia perrieri	44.55	0.00e+00	870.00
IUUC-Loc-052936	Lepisosteus oculatus	54.67	0.00e+00	1077.00
IUUC-Lma-053315	Leptosphaeria maculans	70.03	0.00e+00	1520.00
IUUC-Laf-053948	Loxodonta africana	54.78	0.00e+00	1069.00
IUUC-Mcc-055843	Macaca mulatta	54.34	0.00e+00	1092.00
IUUC-Meu-056258	Macropus eugenii	54.29	0.00e+00	1075.00
IUUC-Mor-057269	Magnaporthe oryzae	89.02	0.00e+00	1919.00
IUUC-Mpo-057435	Magnaporthe poae	96.05	0.00e+00	2028.00
IUUC-Mtr-058572	Medicago truncatula	45.06	0.00e+00	843.00
IUUC-Mla-059176	Melampsora laricipopulina	57.86	0.00e+00	1141.00
IUUC-Mga-059721	Meleagris gallopavo	42.89	0.00e+00	670.00
IUUC-Mvi-060437	Microbotryum violaceum	56.85	0.00e+00	1153.00
IUUC-Mmr-061405	Microcebus murinus	52.98	0.00e+00	1045.00
IUUC-Mdo-062032	Monodelphis domestica	53.09	0.00e+00	1043.00
IUUC-Mmu-063280	Mus musculus	54.15	0.00e+00	1085.00
IUUC-Mac-065505	Musa acuminata	45.38	0.00e+00	854.00
IUUC-Mpu-066409	Mustela putorius furo	54.24	0.00e+00	1094.00
IUUC-Mlu-067217	Myotis lucifugus	53.76	0.00e+00	1077.00
IUUC-Nfi-068407	Neosartorya fischeri	70.30	0.00e+00	1484.00
IUUC-Ncr-068698	Neurospora crassa	79.36	0.00e+00	1722.00
IUUC-Nle-070072	Nomascus leucogenys	51.51	0.00e+00	986.00
IUUC-Opr-070715	Ochotona princeps	37.63	2.00e-176	611.00
IUUC-Ont-071671	Oreochromis niloticus	54.09	0.00e+00	1055.00
IUUC-Oan-073268	Ornithorhynchus anatinus	42.15	0.00e+00	652.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.63	0.00e+00	1102.00
IUUC-Oba-075913	Oryza barthii	45.48	0.00e+00	850.00
IUUC-Obr-076244	Oryza brachyantha	44.73	0.00e+00	858.00
IUUC-Ogl-077887	Oryza glaberrima	43.86	0.00e+00	831.00
IUUC-Ogu-078793	Oryza glumaepatula	45.48	0.00e+00	851.00
IUUC-Oin-079710	Oryza indica	45.48	0.00e+00	848.00
IUUC-Olo-081089	Oryza longistaminata	44.58	0.00e+00	859.00
IUUC-Ome-081942	Oryza meridionalis	43.61	0.00e+00	831.00
IUUC-Oni-082365	Oryza nivara	43.95	0.00e+00	834.00
IUUC-Opu-083301	Oryza punctata	43.73	0.00e+00	837.00
IUUC-Oru-084469	Oryza rufipogon	44.39	0.00e+00	857.00
IUUC-Osa-085949	Oryza sativa	44.05	0.00e+00	840.00
IUUC-Ola-087002	Oryzias latipes	54.52	0.00e+00	1069.00
IUUC-Olu-087687	Ostreococcus lucimarinus	42.70	0.00e+00	756.00
IUUC-Oga-088594	Otolemur garnettii	54.73	0.00e+00	1071.00
IUUC-Oar-090068	Ovis aries	54.39	0.00e+00	1096.00
IUUC-Ptr-090609	Pan troglodytes	42.96	0.00e+00	692.00
IUUC-Pan-092114	Papio anubis	54.24	0.00e+00	1088.00
IUUC-Psi-093489	Pelodiscus sinensis	43.68	0.00e+00	712.00
IUUC-Pma-094214	Petromyzon marinus	47.40	2.00e-40	156.00
IUUC-Pno-095154	Phaeosphaeria nodorum	68.83	0.00e+00	1502.00
IUUC-Ppa-095416	Physcomitrella patens	46.93	0.00e+00	863.00
IUUC-Pfo-097184	Poecilia formosa	53.90	0.00e+00	1056.00
IUUC-Pab-097861	Pongo abelii	54.05	0.00e+00	1056.00
IUUC-Pop-099577	Populus trichocarpa	45.37	0.00e+00	868.00
IUUC-Pca-100347	Procavia capensis	52.38	0.00e+00	909.00
IUUC-Ppe-102012	Prunus persica	44.74	0.00e+00	868.00
IUUC-Pva-102584	Pteropus vampyrus	54.63	0.00e+00	1126.00
IUUC-Pgr-103336	Puccinia graminis	55.63	0.00e+00	1105.00
IUUC-Ptt-103939	Puccinia triticina	55.92	0.00e+00	1098.00
IUUC-Pte-104200	Pyrenophora teres	69.28	0.00e+00	1519.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	69.04	0.00e+00	1507.00
IUUC-Rno-105462	Rattus norvegicus	54.24	0.00e+00	1081.00
IUUC-Sce-106245	Saccharomyces cerevisiae	59.32	0.00e+00	1205.00
IUUC-Sha-107142	Sarcophilus harrisii	53.85	0.00e+00	1074.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	58.32	0.00e+00	1219.00
IUUC-Spo-108034	Schizosaccharomyces pombe	58.48	0.00e+00	1179.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	74.93	0.00e+00	1556.00
IUUC-Smo-108912	Selaginella moellendorffii	46.60	0.00e+00	857.00
IUUC-Sit-110281	Setaria italica	44.61	0.00e+00	855.00
IUUC-Sly-110914	Solanum lycopersicum	45.11	0.00e+00	880.00
IUUC-Stu-112109	Solanum tuberosum	44.63	0.00e+00	883.00
IUUC-Sar-113737	Sorex araneus	54.15	0.00e+00	1088.00
IUUC-Sbi-114774	Sorghum bicolor	45.39	0.00e+00	880.00
IUUC-Sre-115148	Sporisorium reilianum	57.54	0.00e+00	1137.00
IUUC-Ssc-115777	Sus scrofa	54.39	0.00e+00	1093.00
IUUC-Tgu-116565	Taeniopygia guttata	43.90	0.00e+00	709.00
IUUC-Tru-118742	Takifugu rubripes	54.39	0.00e+00	1027.00
IUUC-Tsy-119436	Tarsius syrichta	38.17	2.00e-162	564.00
IUUC-Tni-120401	Tetraodon nigroviridis	54.48	0.00e+00	1031.00
IUUC-Tca-121672	Theobroma cacao	44.74	0.00e+00	860.00
IUUC-Tre-122009	Trichoderma reesei	73.87	0.00e+00	1555.00
IUUC-Tvi-122259	Trichoderma virens	75.05	0.00e+00	1567.00
IUUC-Tae-125676	Triticum aestivum	44.83	0.00e+00	863.00
IUUC-Tur-126189	Triticum urartu	45.01	0.00e+00	807.00
IUUC-Tme-127055	Tuber melanosporum	62.50	0.00e+00	1286.00
IUUC-Tbe-127487	Tupaia belangeri	57.03	4.00e-161	560.00
IUUC-Ttr-128331	Tursiops truncatus	54.44	0.00e+00	1080.00
IUUC-Uma-129387	Ustilago maydis	57.34	0.00e+00	1141.00
IUUC-Vda-129977	Verticillium dahliae	75.92	0.00e+00	1559.00
IUUC-Vpa-130716	Vicugna pacos	41.08	0.00e+00	670.00
IUUC-Vvi-130857	Vitis vinifera	45.42	0.00e+00	872.00
IUUC-Xtr-132947	Xenopus tropicalis	39.39	0.00e+00	644.00
IUUC-Xma-133805	Xiphophorus maculatus	53.80	0.00e+00	1040.00
IUUC-Yli-134547	Yarrowia lipolytica	59.42	0.00e+00	1234.00
IUUC-Zma-134970	Zea mays	44.52	0.00e+00	866.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence