iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115275

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU695053

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011765.2	ENSSSCT00000012876.2	ENSSSCP00000012535.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-40	140.2	2	433
UBD/Alpha-Helix/UBA	7.40e-19	67.5	303	340

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 73   llkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdn 161
           +++ ++k ++efs+++qqDaqEf+ +l++ +e++                               +++  sd+F++ ++++i+c + ++
   Q: 2    FKAFVSKSHPEFSSNRQQDAQEFFLHLVNLVERNR-----------------------------IGSENPSDVFRFLVEERIQCCQTRK 61
           88999***************************998.............................688899**************99999 PP
   S: 162  vssreepfldlslpvpgkeetkke...........................slqdcLesftkeeelegenkyycekckkkqeaekklkl 223
           v   e   + ++lpv ++  t+k                             ++ cL++f+++e++++   ++++  ++k+  +k+ ++
   Q: 62   VRYMERVDYLMQLPVAMEAATNKDeliayeltrreaeanrrplpelvrakiPFSACLQAFSEPENVDD---FWSSALQAKSAGVKTSRF 147
           99888888888888888887776689****************************************97...****************** PP
   S: 224  kklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts............................................. 267
            ++Pe+L++++k+f+f  + ++++k++ ++++p+ Ld+++  ++                                             
   Q: 148  ASFPEYLVVQIKKFTFGLD-WVPKKFDVSIDMPDLLDINHLRARglqpgeeelpdisppivipddskdrlmnqlidpseidessvmqla 235
           ****************997.*******************99988999999999999999999888888888888888888877777777 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 236  emgfpleacrkavyftgnmgaevafnwiivhmeepdfaepltmpgyggaasagasvfgatgldnqppeeivaiitsmgfhrnqavqalr 324
           77777777777777777777777777777777777777777777777777777777777777666666666666666666666666665 PP
   S: 268  ......peekqke...........................................kkkYeLiavvvHsG.slssGHYvayvknekgkW 306
                 +     +                                           + +YeL+a ++H+G s+ sGHYv+++k+ +g+W
   Q: 325  atnsnlE-----RaldwifshpefeedsdfviemennananiiseakpegprvkdgSGTYELFAFISHMGtSTMSGHYVCHIKK-EGRW 407
           5555550.....05555555555555555666666666677788888888888888****************************.9*** PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkr 337
           + ++D+kV ++  e+  +   + +Y++fY+r
   Q: 408  VIYNDHKVCAS--ERPPK---DLGYMYFYRR 433
           ********999..78888...99******98 PP

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraannnleaAveyLldg 41
           e++++ +++MGF r++a+qaLra+n nle+A+++++++
   Q: 303  EEIVAIITSMGFHRNQAVQALRATNSNLERALDWIFSH 340
           899*********************************97 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MFKAFVSKSH PEFSSNRQQD AQEFFLHLVN LVERNRIGSE NPSDVFRFLV EERIQCCQTR 60
KVRYMERVDY LMQLPVAMEA ATNKDELIAY ELTRREAEAN RRPLPELVRA KIPFSACLQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTCATTT TTCAGCCTCA ACAGAATGGG ATCTCTCCAC GAATGTTTAA GGCCTTTGTG 60
AGCAAGAGCC ACCCAGAATT CTCTTCCAAC AGACAGCAGG ATGCCCAAGA ATTTTTCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00973--USP_2
PS50235--USP_3

Pfam

PF00627--UBA
PF00443--UCH

SMART

SM00165--UBA

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-032251	Echinops telfairi	84.63	0.00e+00	688.00
IUUC-Oan-073087	Ornithorhynchus anatinus	77.51	2.00e-74	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence