iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020678

Ensembl Protein ID

ENSCAFP00000043038.1

UniProt Accession

J9PB60; J9PB60_CANLF

Genbank Protein ID

ENSCAFP00000043038

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000066

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000036.3	ENSCAFT00000000054.3	ENSCAFP00000043038.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.20e-17	62.1	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ETDFMVVQQP SLGSDFGKDD SLFGSCYGKD MASCDITNED 60
EKGGKGRSKS ESLMGTLKRR LSAKQKQKGK GSTPSGSSAD EDTFSSSSAP LVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTTAA AACCTTCCGA AAATCTTTCA ACTTGAATAA AAGTAAAGAA 60
GAAACGGATT TCATGGTCGT ACAGCAACCG TCGCTAGGCA GTGATTTTGG AAAAGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001772--C:immunological synapse
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

cfa:100856303

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	97.38	0.00e+00	969.00
IUUC-Apl-004035	Anas platyrhynchos	90.47	0.00e+00	902.00
IUUC-Aca-004782	Anolis carolinensis	87.69	0.00e+00	859.00
IUUC-Afl-008492	Aspergillus flavus	25.62	1.00e-01	31.60
IUUC-Ame-011790	Astyanax mexicanus	70.95	0.00e+00	652.00
IUUC-Bta-012579	Bos taurus	95.22	4.00e-109	388.00
IUUC-Bol-015843	Brassica oleracea	28.77	2.60e-02	33.50
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	94.77	0.00e+00	994.00
IUUC-Cpo-021947	Cavia porcellus	94.95	0.00e+00	1003.00
IUUC-Csa-023935	Chlorocebus sabaeus	94.58	0.00e+00	966.00
IUUC-Cho-024477	Choloepus hoffmanni	91.40	0.00e+00	958.00
IUUC-Cin-025413	Ciona intestinalis	68.24	2.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	5.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	25.00	2.40e-01	30.80
IUUC-Dre-027636	Danio rerio	69.40	0.00e+00	642.00
IUUC-Dno-029048	Dasypus novemcinctus	93.46	0.00e+00	956.00
IUUC-Dor-030401	Dipodomys ordii	91.23	0.00e+00	921.00
IUUC-Ete-033116	Echinops telfairi	49.47	1.00e-59	222.00
IUUC-Eca-033825	Equus caballus	95.89	0.00e+00	929.00
IUUC-Fca-036253	Felis catus	94.21	0.00e+00	883.00
IUUC-Fal-037614	Ficedula albicollis	90.47	0.00e+00	902.00
IUUC-Fox-037898	Fusarium oxysporum	27.16	1.20e-02	33.50
IUUC-Gmo-038928	Gadus morhua	69.93	0.00e+00	680.00
IUUC-Gga-040177	Gallus gallus	89.91	0.00e+00	895.00
IUUC-Gac-042263	Gasterosteus aculeatus	70.48	0.00e+00	703.00
IUUC-Ggo-045288	Gorilla gorilla	94.21	0.00e+00	967.00
IUUC-Hsa-046409	Homo sapiens	94.58	0.00e+00	969.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	94.58	0.00e+00	937.00
IUUC-Lch-050354	Latimeria chalumnae	84.70	0.00e+00	882.00
IUUC-Loc-052319	Lepisosteus oculatus	81.90	0.00e+00	826.00
IUUC-Laf-054070	Loxodonta africana	91.40	0.00e+00	908.00
IUUC-Mcc-055045	Macaca mulatta	94.21	0.00e+00	962.00
IUUC-Meu-055917	Macropus eugenii	90.84	0.00e+00	966.00
IUUC-Mga-059273	Meleagris gallopavo	90.09	0.00e+00	896.00
IUUC-Mmr-061597	Microcebus murinus	95.14	0.00e+00	972.00
IUUC-Mdo-062492	Monodelphis domestica	65.31	2.00e-113	401.00
IUUC-Mmu-063374	Mus musculus	83.46	0.00e+00	832.00
IUUC-Mpu-065967	Mustela putorius furo	91.59	0.00e+00	920.00
IUUC-Mlu-067532	Myotis lucifugus	94.95	0.00e+00	945.00
IUUC-Nle-069373	Nomascus leucogenys	94.77	0.00e+00	969.00
IUUC-Opr-070873	Ochotona princeps	90.84	0.00e+00	959.00
IUUC-Ont-072498	Oreochromis niloticus	70.85	0.00e+00	739.00
IUUC-Oan-072943	Ornithorhynchus anatinus	72.01	3.00e-97	348.00
IUUC-Ocu-073870	Oryctolagus cuniculus	93.46	0.00e+00	954.00
IUUC-Ola-086866	Oryzias latipes	90.23	3.00e-105	374.00
IUUC-Oga-089057	Otolemur garnettii	91.78	0.00e+00	915.00
IUUC-Oar-089841	Ovis aries	62.13	3.00e-169	588.00
IUUC-Ptr-091054	Pan troglodytes	94.58	0.00e+00	967.00
IUUC-Pma-094253	Petromyzon marinus	82.11	2.00e-92	333.00
IUUC-Pfo-097179	Poecilia formosa	65.38	6.00e-177	613.00
IUUC-Pab-097702	Pongo abelii	94.77	0.00e+00	969.00
IUUC-Pca-100671	Procavia capensis	86.64	7.00e-130	457.00
IUUC-Pgr-103542	Puccinia graminis	28.17	2.60e+00	28.50
IUUC-Rno-106044	Rattus norvegicus	80.98	0.00e+00	821.00
IUUC-Sha-107139	Sarcophilus harrisii	89.76	0.00e+00	882.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.50e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.50e-01	30.00
IUUC-Ssc-115343	Sus scrofa	93.27	0.00e+00	958.00
IUUC-Tgu-117061	Taeniopygia guttata	89.91	0.00e+00	899.00
IUUC-Tni-119829	Tetraodon nigroviridis	67.77	0.00e+00	650.00
IUUC-Tae-123723	Triticum aestivum	27.50	1.20e-02	35.40
IUUC-Ttr-129148	Tursiops truncatus	92.71	0.00e+00	907.00
IUUC-Vpa-130780	Vicugna pacos	90.65	0.00e+00	874.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.60e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	83.55	0.00e+00	861.00
IUUC-Xma-133904	Xiphophorus maculatus	69.06	0.00e+00	670.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence