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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063315
UUCD1 version UUC-MuM-00573
Ensembl Protein ID ENSMUSP00000052755.6
UniProt Accession Q80T85; Q80VT3; Q80ZW6; Q8BIP8; Q8BVK5; Q8K0Q6; DCAF5_MOUSE
Genbank Protein ID BAC65843.1; AAH30857.1; AAH42567.1; AAH46813.2; BAC28784.1; BAC37050.1
Protein Name DDB1- and CUL4-associated factor 5; WD repeat-containing protein 22
Genbank Nucleotide ID AK122561; BC030857; BC042567; BC046813; AK034653; AK077889
Gene Name Dcaf5; Kiaa1824; Wdr22
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000049106.6 ENSMUST00000054145.6 ENSMUSP00000052755.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.40e-27 93.6 141 173
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           H+d v++l+    +d++++s+sdDg + +WD+r
   Q: 141  HEDAVYGLSVspvNDNIFASSSDDGRVLIWDIR 173
           9*******9999999****************87 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
 May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Sequence
(Fasta)
MKRRAGLGGS MRSVVGFLSQ RGLHGDPLLT QDFQRRRLRG CRNLYKKDLL GHFGCVNAIE 60
FSNNGGQWLV SGGDDRRVLL WHMEQAIHSR VKPIQLKGEH HSNIFCLAFN SGNTKVFSGG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063315|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGGACGCG ACCGTGAGGA AGCCGCGAAC GCCGCCGACC GACCGTCTGC ACACCTCGCT 60
CCGTCTGCCA TGGCTGGTTA AAGAAGCCTC CGGCTCGCTG CGCGCGGGGA GGGACGGGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063315|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005739--C:mitochondrion
GO:0016567--P:protein ubiquitination
KEGG mmu:320808
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001497 Ailuropoda melanoleuca 89.97 0.00e+00 1507.00
IUUC-Apl-003432 Anas platyrhynchos 70.54 0.00e+00 1080.00
IUUC-Aca-005069 Anolis carolinensis 67.96 0.00e+00 1037.00
IUUC-Ame-011063 Astyanax mexicanus 86.04 0.00e+00 750.00
IUUC-Bta-013013 Bos taurus 89.16 0.00e+00 1468.00
IUUC-Cel-018265 Caenorhabditis elegans 31.22 2.00e-33 137.00
IUUC-Cja-018816 Callithrix jacchus 90.81 0.00e+00 1651.00
IUUC-Cfa-020397 Canis familiaris 90.81 0.00e+00 1589.00
IUUC-Cpo-021999 Cavia porcellus 88.26 0.00e+00 1432.00
IUUC-Csa-024256 Chlorocebus sabaeus 91.02 0.00e+00 1653.00
IUUC-Cho-024707 Choloepus hoffmanni 84.34 0.00e+00 1335.00
IUUC-Cin-025728 Ciona intestinalis 46.67 5.00e-53 200.00
IUUC-Dre-027683 Danio rerio 87.27 0.00e+00 761.00
IUUC-Dno-029603 Dasypus novemcinctus 90.71 0.00e+00 1595.00
IUUC-Dme-031660 Drosophila melanogaster 45.09 5.00e-92 332.00
IUUC-Ete-032701 Echinops telfairi 83.11 0.00e+00 1327.00
IUUC-Eca-033345 Equus caballus 90.29 0.00e+00 1486.00
IUUC-Eeu-034973 Erinaceus europaeus 81.92 0.00e+00 855.00
IUUC-Fca-036007 Felis catus 91.24 0.00e+00 1610.00
IUUC-Fal-036759 Ficedula albicollis 70.08 0.00e+00 1071.00
IUUC-Gmo-039095 Gadus morhua 85.12 0.00e+00 763.00
IUUC-Gga-040850 Gallus gallus 96.42 2.00e-159 555.00
IUUC-Gac-041422 Gasterosteus aculeatus 84.84 0.00e+00 764.00
IUUC-Ggo-045451 Gorilla gorilla 90.71 0.00e+00 1620.00
IUUC-Hsa-046752 Homo sapiens 90.81 0.00e+00 1578.00
IUUC-Itr-048562 Ictidomys tridecemlineatus 85.29 0.00e+00 990.00
IUUC-Lch-049676 Latimeria chalumnae 59.40 0.00e+00 977.00
IUUC-Loc-052200 Lepisosteus oculatus 86.13 0.00e+00 755.00
IUUC-Laf-053783 Loxodonta africana 89.42 0.00e+00 1450.00
IUUC-Mcc-055495 Macaca mulatta 91.02 0.00e+00 1654.00
IUUC-Meu-056044 Macropus eugenii 78.17 0.00e+00 1219.00
IUUC-Mga-059650 Meleagris gallopavo 69.32 0.00e+00 920.00
IUUC-Mvi-060289 Microbotryum violaceum 26.72 4.00e-13 69.30
IUUC-Mdo-063059 Monodelphis domestica 82.28 0.00e+00 1394.00
IUUC-Mpu-066563 Mustela putorius furo 88.67 0.00e+00 1345.00
IUUC-Mlu-067408 Myotis lucifugus 89.27 0.00e+00 1431.00
IUUC-Nle-069574 Nomascus leucogenys 90.92 0.00e+00 1651.00
IUUC-Opr-070491 Ochotona princeps 78.10 0.00e+00 1334.00
IUUC-Ont-071270 Oreochromis niloticus 85.01 0.00e+00 775.00
IUUC-Oan-073632 Ornithorhynchus anatinus 77.65 0.00e+00 843.00
IUUC-Ocu-074329 Oryctolagus cuniculus 89.86 0.00e+00 1597.00
IUUC-Ola-087017 Oryzias latipes 84.62 3.00e-143 500.00
IUUC-Oga-088295 Otolemur garnettii 85.70 0.00e+00 1533.00
IUUC-Oar-089609 Ovis aries 85.74 0.00e+00 1437.00
IUUC-Ptr-090891 Pan troglodytes 90.71 0.00e+00 1573.00
IUUC-Pan-092220 Papio anubis 90.86 0.00e+00 1618.00
IUUC-Psi-093097 Pelodiscus sinensis 58.15 2.00e-157 549.00
IUUC-Pfo-096844 Poecilia formosa 83.20 0.00e+00 630.00
IUUC-Pab-098512 Pongo abelii 91.02 0.00e+00 1655.00
IUUC-Pca-100999 Procavia capensis 83.46 0.00e+00 1357.00
IUUC-Pva-102524 Pteropus vampyrus 90.18 0.00e+00 1578.00
IUUC-Pgr-103528 Puccinia graminis 24.78 8.00e-30 125.00
IUUC-Rno-104861 Rattus norvegicus 95.45 0.00e+00 1692.00
IUUC-Sha-106554 Sarcophilus harrisii 95.98 2.00e-128 451.00
IUUC-Sar-113644 Sorex araneus 84.07 2.00e-166 580.00
IUUC-Sre-114948 Sporisorium reilianum 27.12 3.00e-22 100.00
IUUC-Ssc-115431 Sus scrofa 100.00 9.00e-79 284.00
IUUC-Tgu-117355 Taeniopygia guttata 72.86 0.00e+00 1174.00
IUUC-Tru-118672 Takifugu rubripes 81.92 0.00e+00 750.00
IUUC-Tni-120215 Tetraodon nigroviridis 74.72 0.00e+00 672.00
IUUC-Ttr-128965 Tursiops truncatus 94.39 0.00e+00 1026.00
IUUC-Vpa-130586 Vicugna pacos 86.16 0.00e+00 1365.00
IUUC-Xtr-132611 Xenopus tropicalis 59.52 0.00e+00 930.00
Created Date 25-Jun-2017

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