iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026096

UUCD1 version

UUC-CiS-00020

Ensembl Protein ID

ENSCSAVP00000004060.1

UniProt Accession

H2YFG2; H2YFG2_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000002397.1	ENSCSAVT00000004118.1	ENSCSAVP00000004058.1
ENSCSAVG00000002397.1	ENSCSAVT00000004119.1	ENSCSAVP00000004059.1
ENSCSAVG00000002397.1	ENSCSAVT00000004120.1	ENSCSAVP00000004060.1
ENSCSAVG00000002397.1	ENSCSAVT00000004121.1	ENSCSAVP00000004061.1
ENSCSAVG00000002397.1	ENSCSAVT00000004122.1	ENSCSAVP00000004062.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.00e-137	458.9	14	460

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk...vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrk 85
           l ++v+k+ +   + +  +++ ++++y lc+++   +g++lY ++k +l +++k+++k+v++  +e++L  y + We +++++++l+ 
   Q: 14   LSDTVEKVITAAPLaRPVWNDKFSDIYSLCIAYpeaLGENLYSATKSFLSAHVKKLSKDVHHC-GEDFLTSYAKNWETYSQGAVYLNL 100
           778999*****999999***************9999************************987.888********************* PP
   S: 86   ifayldrtyvkk................skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvve..slve 155
           ++ +++++yv k                ++++ e+++La+++w++ ++ ++++rl+++llk i+++R+g+   ++     v+  slv 
   Q: 101  LYHHFNHQYVTKskqndadieygfitddKEQMLEIKDLAMEAWKEGMLVPLQHRLVNALLKDIAKDREGDLSGKNTKIHQVAlySLVA 188
           ************99999999999999888888*************************************9987666555555015566 PP
   S: 156  Lslnk....laiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesl 239
           ++++k    l+ y++ FE++fl++t e+y+a++ e+l+ + ++eY++kv + l++ee r +r+l+ s+++k + +++++ i +h+++l
   Q: 189  VEQHKkrnaLKYYEDTFEKLFLQQTGEYYRAKALELLNDSTCSEYMNKVLSLLTDEEMRNRRFLHISSYKKTTLECQQRVIIDHIKFL 276
           655559999******************************************************************************* PP
   S: 240  laelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlk 327
           +a++ +++r++ t dl +my Ll+ v ngl +++ ele+hike g++++   ++ + p ++Ve++le+++++++l++  Fn d+ F++
   Q: 277  QAGCRQMIRHNSTTDLLHMYMLLKSVANGLTHMVSELEAHIKETGLELVKGIKEGNIPLQFVETILEVHKRFHDLIRDTFNSDKLFVS 364
           **************************************************************************************** PP
   S: 328  aldkafetfvnknsvlka............................akspEllA..ryiDqlLrksskglteeeleaqldkvllvfky 385
           ald a+ ++vn  + ++                              +   +lA  +y+D  Lr+ +kg+ + + +++l++ +lvf+y
   Q: 365  ALDRACIAAVNYSEPKQPckapelvsliiitfntsctiphffvlgeLRIQQQLAvcKYCDAILRRCAKGP-SSDADDKLQSSILVFRY 451
           *************99998999*************************88888887669*********9997.5689************* PP
   S: 386  isekdvFek 394
           i++kdvF+k
   Q: 452  IDDKDVFQK 460
           *******97 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MSRRINFIET WDKLSDTVEK VITAAPLARP VWNDKFSDIY SLCIAYPEAL GENLYSATKS 60
FLSAHVKKLS KDVHHCGEDF LTSYAKNWET YSQGAVYLNL LYHHFNHQYV TKSKQNDADI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGTGCAA TCAGCATTAT AGGAATATTT TTAAAAATGA ATGCAAAAAG ATAGTTGGAT 60
ATTCTACACC GGGATGTCAC GTCGTATAAA CTTCATTGAG ACATGGGATA AATTGTCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001969	Ailuropoda melanoleuca	41.77	0.00e+00	662.00
IUUC-Apl-004067	Anas platyrhynchos	42.00	0.00e+00	663.00
IUUC-Aca-004534	Anolis carolinensis	40.87	0.00e+00	649.00
IUUC-Ame-011695	Astyanax mexicanus	41.41	0.00e+00	666.00
IUUC-Bta-013074	Bos taurus	41.77	0.00e+00	660.00
IUUC-Cel-018431	Caenorhabditis elegans	32.91	8.00e-127	446.00
IUUC-Cja-019371	Callithrix jacchus	41.65	0.00e+00	660.00
IUUC-Cfa-020508	Canis familiaris	41.77	0.00e+00	662.00
IUUC-Cpo-021851	Cavia porcellus	41.85	0.00e+00	663.00
IUUC-Csa-023583	Chlorocebus sabaeus	41.65	0.00e+00	658.00
IUUC-Cho-024308	Choloepus hoffmanni	44.03	1.00e-84	305.00
IUUC-Cin-025350	Ciona intestinalis	72.74	0.00e+00	1236.00
IUUC-Dre-028828	Danio rerio	41.41	0.00e+00	660.00
IUUC-Dno-029709	Dasypus novemcinctus	41.65	0.00e+00	660.00
IUUC-Dor-030319	Dipodomys ordii	34.80	4.00e-109	387.00
IUUC-Dme-031938	Drosophila melanogaster	35.86	3.00e-154	537.00
IUUC-Ete-032756	Echinops telfairi	36.64	1.00e-96	345.00
IUUC-Eca-034019	Equus caballus	41.65	0.00e+00	660.00
IUUC-Eeu-034914	Erinaceus europaeus	40.97	2.00e-126	444.00
IUUC-Fca-035926	Felis catus	41.77	0.00e+00	662.00
IUUC-Fal-037627	Ficedula albicollis	41.89	0.00e+00	660.00
IUUC-Gmo-038728	Gadus morhua	41.72	0.00e+00	659.00
IUUC-Gga-040820	Gallus gallus	40.69	0.00e+00	648.00
IUUC-Gac-041293	Gasterosteus aculeatus	41.12	0.00e+00	654.00
IUUC-Ggo-045235	Gorilla gorilla	40.52	0.00e+00	637.00
IUUC-Hsa-046819	Homo sapiens	41.65	0.00e+00	660.00
IUUC-Itr-048063	Ictidomys tridecemlineatus	42.76	8.00e-102	362.00
IUUC-Lch-049443	Latimeria chalumnae	41.62	0.00e+00	655.00
IUUC-Loc-052798	Lepisosteus oculatus	41.95	0.00e+00	664.00
IUUC-Laf-053379	Loxodonta africana	41.85	0.00e+00	662.00
IUUC-Mcc-055702	Macaca mulatta	41.65	0.00e+00	660.00
IUUC-Meu-056223	Macropus eugenii	31.29	9.00e-102	362.00
IUUC-Mga-060034	Meleagris gallopavo	41.89	0.00e+00	660.00
IUUC-Mmr-061090	Microcebus murinus	41.53	0.00e+00	658.00
IUUC-Mdo-062530	Monodelphis domestica	41.89	0.00e+00	663.00
IUUC-Mmu-063857	Mus musculus	41.62	0.00e+00	642.00
IUUC-Mpu-065915	Mustela putorius furo	41.77	0.00e+00	661.00
IUUC-Mlu-068049	Myotis lucifugus	41.65	0.00e+00	661.00
IUUC-Nle-069102	Nomascus leucogenys	41.85	2.00e-141	494.00
IUUC-Opr-071197	Ochotona princeps	35.56	1.00e-139	488.00
IUUC-Ont-071902	Oreochromis niloticus	41.29	0.00e+00	661.00
IUUC-Oan-073307	Ornithorhynchus anatinus	40.44	0.00e+00	649.00
IUUC-Ocu-074703	Oryctolagus cuniculus	41.53	0.00e+00	660.00
IUUC-Ola-086789	Oryzias latipes	40.95	0.00e+00	653.00
IUUC-Oga-088480	Otolemur garnettii	41.65	0.00e+00	658.00
IUUC-Oar-089899	Ovis aries	41.77	0.00e+00	662.00
IUUC-Ptr-090965	Pan troglodytes	41.65	0.00e+00	661.00
IUUC-Pan-092920	Papio anubis	40.24	3.00e-179	620.00
IUUC-Psi-093122	Pelodiscus sinensis	41.89	0.00e+00	660.00
IUUC-Pma-094656	Petromyzon marinus	42.00	0.00e+00	674.00
IUUC-Pfo-096342	Poecilia formosa	41.29	0.00e+00	657.00
IUUC-Pab-097544	Pongo abelii	41.65	0.00e+00	660.00
IUUC-Pca-100564	Procavia capensis	39.22	1.00e-93	335.00
IUUC-Pva-102179	Pteropus vampyrus	40.60	3.00e-79	288.00
IUUC-Rno-105439	Rattus norvegicus	41.74	0.00e+00	644.00
IUUC-Sha-106654	Sarcophilus harrisii	41.89	0.00e+00	664.00
IUUC-Sar-113138	Sorex araneus	38.90	2.00e-172	597.00
IUUC-Ssc-115543	Sus scrofa	40.59	2.00e-129	454.00
IUUC-Tgu-117095	Taeniopygia guttata	41.41	0.00e+00	658.00
IUUC-Tru-118593	Takifugu rubripes	42.97	0.00e+00	665.00
IUUC-Tsy-119621	Tarsius syrichta	38.81	5.00e-118	416.00
IUUC-Tni-119697	Tetraodon nigroviridis	41.77	0.00e+00	664.00
IUUC-Tbe-127831	Tupaia belangeri	36.72	6.00e-140	489.00
IUUC-Ttr-129108	Tursiops truncatus	41.77	0.00e+00	661.00
IUUC-Vpa-130414	Vicugna pacos	41.86	3.00e-87	314.00
IUUC-Xtr-132054	Xenopus tropicalis	41.53	0.00e+00	657.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence