iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054544

UUCD1 version

UUC-LoA-00321

Ensembl Protein ID

ENSLAFP00000007953.3

UniProt Accession

G3T3T6; G3T3T6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009480.3	ENSLAFT00000009481.3	ENSLAFP00000007953.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-18	66.5	123	155
UBD/Beta-Prp	3.00e-40	138.6	194	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++  ++++vsGs+D t kvW + +g+
   Q: 123  HEQEVNCVDCKGGIIVSGSRDRTAKVWPFASGR 155
           99*******9449**************988887 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq....tgecvrtlng.htdnvksvrfspnderlvsgs.s 242
           +r+Wdl++g+l+++l ++  +    l++ ++    l+s+++d++v++wdl+    + +cv+++++ h+++ ++++++  +++l++gs  
   Q: 194  LRIWDLNSGQLMTHLGSDFPPGAGVLDVMYETpSTLLSCGYDTYVRYWDLRtsvrNRKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsY 281
           79*************99999999999988888689*******************99********999**********.99999999978 PP
   S: 243  DgsiriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
            g++r+Wd r++ +l+++ l+    +++v +l+f+ ++l+++ +  ++++++++
   Q: 282  YGVVRLWDRRQRACLHAFPLTStPLSSPVYCLRFTTKHLYAALS-YNLHVLDFQ 334
           9*******************99667889***********99866.467777765 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

GLSVLSGHRM AGVPVKERVK VSQNWRLGRC REGILLKWRC SQMPWMQLEG DSLYISQANF 60
ILAYQFRPDG ASLSRRPLGV FAGHDEDVCH FVLANSHIIS AGGDGKIGVH KIHSTFTVKY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATTATCTG TTCTTTCTGG ACACAGGATG GCCGGTGTCC CAGTGAAGGA ACGGGTGAAG 60
GTGTCTCAGA ACTGGAGGTT GGGGCGCTGC CGAGAGGGGA TTCTGCTAAA GTGGAGATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	95.24	0.00e+00	664.00
IUUC-Apl-003837	Anas platyrhynchos	72.39	3.00e-143	500.00
IUUC-Aca-004776	Anolis carolinensis	67.87	6.00e-122	430.00
IUUC-Ame-010651	Astyanax mexicanus	61.28	8.00e-113	399.00
IUUC-Bta-013495	Bos taurus	94.05	0.00e+00	629.00
IUUC-Cja-018901	Callithrix jacchus	94.64	0.00e+00	630.00
IUUC-Cfa-021251	Canis familiaris	94.35	0.00e+00	657.00
IUUC-Cpo-021750	Cavia porcellus	92.97	0.00e+00	639.00
IUUC-Csa-024026	Chlorocebus sabaeus	94.35	0.00e+00	658.00
IUUC-Cho-024496	Choloepus hoffmanni	71.13	2.00e-132	464.00
IUUC-Cin-025142	Ciona intestinalis	31.16	2.00e-18	85.50
IUUC-Csv-025883	Ciona savignyi	37.18	3.00e-62	232.00
IUUC-Dre-027447	Danio rerio	60.99	4.00e-113	401.00
IUUC-Dno-029572	Dasypus novemcinctus	87.91	4.00e-170	591.00
IUUC-Dor-030982	Dipodomys ordii	96.94	8.00e-171	592.00
IUUC-Dme-031804	Drosophila melanogaster	22.87	6.00e-11	62.00
IUUC-Ete-032917	Echinops telfairi	95.72	0.00e+00	655.00
IUUC-Eca-033969	Equus caballus	94.64	0.00e+00	630.00
IUUC-Eeu-034850	Erinaceus europaeus	83.04	5.00e-164	570.00
IUUC-Fca-036182	Felis catus	94.94	0.00e+00	663.00
IUUC-Fal-037391	Ficedula albicollis	71.69	9.00e-139	486.00
IUUC-Gmo-038632	Gadus morhua	59.44	1.00e-111	396.00
IUUC-Gga-040783	Gallus gallus	71.77	2.00e-144	505.00
IUUC-Gac-042314	Gasterosteus aculeatus	57.67	2.00e-92	332.00
IUUC-Ggo-044739	Gorilla gorilla	94.64	0.00e+00	658.00
IUUC-Hsa-046705	Homo sapiens	94.35	0.00e+00	629.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	97.59	1.00e-169	588.00
IUUC-Loc-052397	Lepisosteus oculatus	67.59	3.00e-126	444.00
IUUC-Meu-056363	Macropus eugenii	59.02	3.00e-102	364.00
IUUC-Mga-059275	Meleagris gallopavo	73.60	2.00e-144	504.00
IUUC-Mmr-060906	Microcebus murinus	94.35	0.00e+00	656.00
IUUC-Mdo-062400	Monodelphis domestica	77.06	5.00e-154	536.00
IUUC-Mmu-063556	Mus musculus	90.77	0.00e+00	636.00
IUUC-Mpu-066500	Mustela putorius furo	94.94	0.00e+00	662.00
IUUC-Mlu-068074	Myotis lucifugus	96.64	0.00e+00	657.00
IUUC-Nle-069601	Nomascus leucogenys	94.64	0.00e+00	659.00
IUUC-Opr-070904	Ochotona princeps	83.00	7.00e-121	426.00
IUUC-Ont-072679	Oreochromis niloticus	56.66	4.00e-108	384.00
IUUC-Oan-073434	Ornithorhynchus anatinus	69.61	7.00e-67	246.00
IUUC-Ocu-074649	Oryctolagus cuniculus	95.11	0.00e+00	651.00
IUUC-Ola-087336	Oryzias latipes	50.46	1.00e-86	313.00
IUUC-Oga-088590	Otolemur garnettii	91.37	1.00e-176	612.00
IUUC-Oar-090178	Ovis aries	96.33	1.00e-180	625.00
IUUC-Pan-092881	Papio anubis	94.64	0.00e+00	658.00
IUUC-Pfo-096176	Poecilia formosa	57.67	2.00e-96	345.00
IUUC-Pab-098285	Pongo abelii	94.64	0.00e+00	659.00
IUUC-Pca-100888	Procavia capensis	90.18	2.00e-175	607.00
IUUC-Pva-102184	Pteropus vampyrus	78.87	2.00e-151	528.00
IUUC-Rno-105668	Rattus norvegicus	90.18	0.00e+00	633.00
IUUC-Sha-106629	Sarcophilus harrisii	78.09	9.00e-155	539.00
IUUC-Ssc-116183	Sus scrofa	96.13	0.00e+00	669.00
IUUC-Tgu-116630	Taeniopygia guttata	70.57	5.00e-143	500.00
IUUC-Tru-118761	Takifugu rubripes	54.52	1.00e-100	359.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.45	7.00e-59	219.00
IUUC-Ttr-128582	Tursiops truncatus	93.15	8.00e-178	615.00
IUUC-Vpa-130431	Vicugna pacos	75.54	1.00e-96	346.00
IUUC-Xtr-132655	Xenopus tropicalis	67.29	2.00e-129	455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence