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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-106059
UUCD1 version UUC-RaN-00912
Ensembl Protein ID ENSRNOP00000022144.3
UniProt Accession Q6DKY8; Q6DKY8_RAT
Genbank Protein ID AAT75221.1; EDM10134.1
Protein Name Ectodermal-neural cortex 1; Nuclear restricted protein in brain; RCG44464
Genbank Nucleotide ID AABR07007780; CH473955
Gene Name Enc1; rCG_44464
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000016541.5 ENSRNOT00000022144.5 ENSRNOP00000022144.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 2.50e-20 73.0 46 114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 5.30e-08 32.1 146 177
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l+ g++ f++h++vLaa+S++F+a+f+++l+es+  ++v+++  + pev++ ll++ Y++++ +ne
   Q: 46   TDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQ-DSEVNFDNsIHPEVLELLLDYAYSSRVIINE 114
           7************************************9.*******77******************9987 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclg+l ++d+++c++L++   +++l++F+
   Q: 146  PTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQ 177
           78*****************************6 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MSVSVHENRK SRASSGSINI YLFHKSSYAD SVLTHLNLLR QQRLFTDVLL HAGNRTFPCH 60
RAVLAACSRY FEAMFSGGLK ESQDSEVNFD NSIHPEVLEL LLDYAYSSRV IINEENAESL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-106059|E3,BTB_3-box|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGCCGCCGC AGGCTCACTC TCCCCTGGCT AGGCGAGCGC CCGCAGACGC TTGGCCCGGC 60
CGGGGCGCCA GGTCCGTAGC TGCTGATCGG GAGACCGAGA TCAGCTGCCT GCCGGAGCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-106059|E3,BTB_3-box|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030562--ENC1
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0043025--C:neuronal cell body
GO:0000790--C:nuclear chromatin
GO:0016363--C:nuclear matrix
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0017148--P:negative regulation of translation
GO:0010976--P:positive regulation of neuron projection development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
KEGG rno:294674
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001434 Ailuropoda melanoleuca 99.66 0.00e+00 1191.00
IUUC-Apl-004096 Anas platyrhynchos 97.28 0.00e+00 1170.00
IUUC-Aca-004884 Anolis carolinensis 96.94 0.00e+00 1160.00
IUUC-Ame-011321 Astyanax mexicanus 88.79 0.00e+00 1115.00
IUUC-Bta-013178 Bos taurus 99.49 0.00e+00 1189.00
IUUC-Cja-019494 Callithrix jacchus 99.66 0.00e+00 1191.00
IUUC-Cfa-020824 Canis familiaris 99.66 0.00e+00 1191.00
IUUC-Cpo-021874 Cavia porcellus 99.32 0.00e+00 1187.00
IUUC-Csa-023075 Chlorocebus sabaeus 99.66 0.00e+00 1191.00
IUUC-Cho-024542 Choloepus hoffmanni 99.32 0.00e+00 1189.00
IUUC-Dre-028448 Danio rerio 88.96 0.00e+00 1120.00
IUUC-Dno-029952 Dasypus novemcinctus 99.66 0.00e+00 1192.00
IUUC-Dor-030844 Dipodomys ordii 99.66 0.00e+00 1191.00
IUUC-Ete-032817 Echinops telfairi 92.02 0.00e+00 1093.00
IUUC-Eca-033651 Equus caballus 99.66 0.00e+00 1191.00
IUUC-Fca-036541 Felis catus 99.66 0.00e+00 1191.00
IUUC-Fal-036968 Ficedula albicollis 97.28 0.00e+00 1169.00
IUUC-Gmo-038821 Gadus morhua 88.29 0.00e+00 1105.00
IUUC-Gga-040468 Gallus gallus 97.28 0.00e+00 1170.00
IUUC-Gac-041686 Gasterosteus aculeatus 89.47 0.00e+00 1117.00
IUUC-Ggo-044621 Gorilla gorilla 99.66 0.00e+00 1191.00
IUUC-Hsa-046983 Homo sapiens 99.49 0.00e+00 1188.00
IUUC-Itr-048320 Ictidomys tridecemlineatus 99.49 0.00e+00 1190.00
IUUC-Lch-049735 Latimeria chalumnae 92.70 0.00e+00 1109.00
IUUC-Loc-052350 Lepisosteus oculatus 92.19 0.00e+00 1145.00
IUUC-Laf-054117 Loxodonta africana 99.32 0.00e+00 1190.00
IUUC-Mcc-054626 Macaca mulatta 99.66 0.00e+00 1191.00
IUUC-Meu-056763 Macropus eugenii 98.64 0.00e+00 1181.00
IUUC-Mmr-060579 Microcebus murinus 99.66 0.00e+00 1191.00
IUUC-Mdo-061995 Monodelphis domestica 98.64 0.00e+00 1181.00
IUUC-Mmu-064206 Mus musculus 99.83 0.00e+00 1193.00
IUUC-Mpu-066884 Mustela putorius furo 99.66 0.00e+00 1191.00
IUUC-Mlu-067183 Myotis lucifugus 99.66 0.00e+00 1191.00
IUUC-Nle-069928 Nomascus leucogenys 99.66 0.00e+00 1191.00
IUUC-Opr-070238 Ochotona princeps 99.32 0.00e+00 1185.00
IUUC-Ont-072404 Oreochromis niloticus 89.81 0.00e+00 1123.00
IUUC-Oan-073303 Ornithorhynchus anatinus 97.96 0.00e+00 1173.00
IUUC-Ocu-074119 Oryctolagus cuniculus 99.32 0.00e+00 1187.00
IUUC-Ola-087510 Oryzias latipes 89.73 0.00e+00 1073.00
IUUC-Oga-089119 Otolemur garnettii 99.66 0.00e+00 1191.00
IUUC-Oar-090036 Ovis aries 92.87 0.00e+00 1062.00
IUUC-Ptr-091349 Pan troglodytes 99.66 0.00e+00 1191.00
IUUC-Pan-092098 Papio anubis 99.66 0.00e+00 1191.00
IUUC-Pma-094515 Petromyzon marinus 60.17 0.00e+00 676.00
IUUC-Pfo-097496 Poecilia formosa 90.32 0.00e+00 1128.00
IUUC-Pab-098388 Pongo abelii 99.66 0.00e+00 1191.00
IUUC-Pca-100511 Procavia capensis 91.17 0.00e+00 1069.00
IUUC-Pva-102964 Pteropus vampyrus 99.66 0.00e+00 1191.00
IUUC-Sha-106470 Sarcophilus harrisii 98.64 0.00e+00 1181.00
IUUC-Sar-113403 Sorex araneus 98.81 0.00e+00 1221.00
IUUC-Ssc-115566 Sus scrofa 99.66 0.00e+00 1191.00
IUUC-Tgu-117331 Taeniopygia guttata 97.11 0.00e+00 1168.00
IUUC-Tru-117890 Takifugu rubripes 89.30 0.00e+00 1115.00
IUUC-Tni-120381 Tetraodon nigroviridis 74.74 0.00e+00 895.00
IUUC-Xtr-131810 Xenopus tropicalis 93.89 0.00e+00 1142.00
Created Date 25-Jun-2017

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