iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095212

Ensembl Protein ID

PP1S112_190V6.1

UniProt Accession

A9SSC3; A9SSC3_PHYPA

Genbank Protein ID

EDQ65934.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

DS545001

Gene Name

PHYPADRAFT_215197

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S112_190V6	PP1S112_190V6.1	PP1S112_190V6.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.06	9.00e-38	154.00	IUUC-Dme-031755
E3 activity/RING/RING	36.19	2.00e-39	160.00	IUUC-Hsa-046357
E3 activity/RING/RING	36.19	9.00e-40	161.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Physcomitrella patens

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPSNAKMEI PESPIREGDT PSSTESETES GVVSKSTLPV ARKPAGTPSS SVHELLECPV 60
CTNSMYPPIH QCPNGHTLCS NCKQRVHNRC PTCRYELGNI RCLALEKVAE SLELPCRYQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCAT CCAATGCGAA GATGGAAATT CCAGAATCAC CAATTCGAGA GGGTGACACC 60
CCTTCGAGCA CTGAGTCAGA GACGGAGTCG GGAGTTGTTT CGAAAAGCAC TTTGCCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppp:PHYPADRAFT_215197

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	67.73	5.00e-125	439.00
IUUC-Aml-001186	Ailuropoda melanoleuca	36.19	3.00e-41	161.00
IUUC-Atr-003118	Amborella trichopoda	79.53	2.00e-142	497.00
IUUC-Apl-003813	Anas platyrhynchos	36.19	3.00e-41	161.00
IUUC-Aca-005014	Anolis carolinensis	36.19	3.00e-41	161.00
IUUC-Aly-006207	Arabidopsis lyrata	74.44	1.00e-137	481.00
IUUC-Ath-007092	Arabidopsis thaliana	86.43	1.00e-139	488.00
IUUC-Ame-011196	Astyanax mexicanus	34.38	4.00e-41	160.00
IUUC-Bta-012887	Bos taurus	36.19	3.00e-41	161.00
IUUC-Bdi-014729	Brachypodium distachyon	85.17	1.00e-140	491.00
IUUC-Bol-015523	Brassica oleracea	86.05	2.00e-137	481.00
IUUC-Bra-017336	Brassica rapa	85.27	3.00e-137	480.00
IUUC-Cel-018320	Caenorhabditis elegans	32.65	6.00e-36	144.00
IUUC-Cja-019796	Callithrix jacchus	36.19	3.00e-41	161.00
IUUC-Cfa-020642	Canis familiaris	34.65	5.00e-42	164.00
IUUC-Cpo-022348	Cavia porcellus	36.19	3.00e-41	161.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.19	3.00e-41	161.00
IUUC-Cho-024933	Choloepus hoffmanni	36.14	8.00e-38	149.00
IUUC-Cin-025674	Ciona intestinalis	35.37	3.00e-41	161.00
IUUC-Csv-026233	Ciona savignyi	35.77	2.00e-41	161.00
IUUC-Dre-028041	Danio rerio	35.82	5.00e-41	160.00
IUUC-Dno-029764	Dasypus novemcinctus	34.80	3.00e-42	164.00
IUUC-Dor-030489	Dipodomys ordii	30.81	1.00e-18	85.10
IUUC-Dme-031755	Drosophila melanogaster	35.11	1.00e-40	159.00
IUUC-Ete-032423	Echinops telfairi	35.38	4.00e-41	160.00
IUUC-Eca-033536	Equus caballus	36.19	3.00e-41	161.00
IUUC-Eeu-035314	Erinaceus europaeus	35.23	2.00e-41	162.00
IUUC-Fca-035362	Felis catus	36.19	2.00e-41	161.00
IUUC-Fal-037487	Ficedula albicollis	35.02	2.00e-41	162.00
IUUC-Gmo-039091	Gadus morhua	35.58	1.00e-37	149.00
IUUC-Gga-040269	Gallus gallus	36.19	3.00e-41	161.00
IUUC-Gac-042282	Gasterosteus aculeatus	35.82	4.00e-41	160.00
IUUC-Gma-042926	Glycine max	78.76	3.00e-145	506.00
IUUC-Ggo-045444	Gorilla gorilla	36.19	3.00e-41	161.00
IUUC-Hsa-046357	Homo sapiens	36.19	3.00e-41	161.00
IUUC-Hvu-047574	Hordeum vulgare	67.20	3.00e-125	440.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.19	3.00e-41	161.00
IUUC-Lch-049504	Latimeria chalumnae	36.19	3.00e-41	161.00
IUUC-Lpe-050879	Leersia perrieri	69.48	2.00e-127	447.00
IUUC-Loc-052191	Lepisosteus oculatus	34.72	2.00e-41	162.00
IUUC-Laf-053668	Loxodonta africana	36.19	3.00e-41	161.00
IUUC-Mcc-054640	Macaca mulatta	36.19	3.00e-41	161.00
IUUC-Meu-055922	Macropus eugenii	35.74	3.00e-36	144.00
IUUC-Mtr-058699	Medicago truncatula	86.64	1.00e-142	498.00
IUUC-Mga-059503	Meleagris gallopavo	36.19	4.00e-41	160.00
IUUC-Mmr-060794	Microcebus murinus	36.19	3.00e-41	161.00
IUUC-Mdo-061971	Monodelphis domestica	35.74	2.00e-37	148.00
IUUC-Mmu-064129	Mus musculus	36.19	2.00e-41	161.00
IUUC-Mac-065670	Musa acuminata	88.01	2.00e-144	504.00
IUUC-Mpu-066488	Mustela putorius furo	36.19	3.00e-41	161.00
IUUC-Mlu-067207	Myotis lucifugus	34.84	2.00e-41	162.00
IUUC-Nle-069706	Nomascus leucogenys	36.19	3.00e-41	160.00
IUUC-Opr-070341	Ochotona princeps	28.31	2.00e-13	68.90
IUUC-Ont-071849	Oreochromis niloticus	35.82	4.00e-41	160.00
IUUC-Oan-073701	Ornithorhynchus anatinus	25.50	2.00e-12	65.90
IUUC-Ocu-074876	Oryctolagus cuniculus	36.19	4.00e-41	160.00
IUUC-Oba-075789	Oryza barthii	78.47	2.00e-138	484.00
IUUC-Obr-076037	Oryza brachyantha	83.33	1.00e-137	481.00
IUUC-Ogl-077148	Oryza glaberrima	78.47	2.00e-138	484.00
IUUC-Ogu-078042	Oryza glumaepatula	78.47	1.00e-138	484.00
IUUC-Oin-079325	Oryza indica	83.33	6.00e-138	482.00
IUUC-Olo-080244	Oryza longistaminata	78.47	1.00e-138	485.00
IUUC-Ome-081318	Oryza meridionalis	70.13	1.00e-127	447.00
IUUC-Oni-082163	Oryza nivara	78.47	2.00e-138	484.00
IUUC-Opu-084065	Oryza punctata	69.81	3.00e-127	447.00
IUUC-Oru-084833	Oryza rufipogon	83.33	6.00e-138	482.00
IUUC-Osa-085316	Oryza sativa	83.33	6.00e-138	482.00
IUUC-Ola-086814	Oryzias latipes	35.82	4.00e-41	160.00
IUUC-Oga-088114	Otolemur garnettii	36.82	6.00e-43	166.00
IUUC-Oar-089323	Ovis aries	36.19	3.00e-41	161.00
IUUC-Ptr-090692	Pan troglodytes	36.19	4.00e-41	160.00
IUUC-Pan-092012	Papio anubis	36.19	3.00e-41	161.00
IUUC-Psi-093687	Pelodiscus sinensis	36.19	2.00e-41	161.00
IUUC-Pma-094387	Petromyzon marinus	34.32	8.00e-41	159.00
IUUC-Pfo-097134	Poecilia formosa	35.82	4.00e-41	160.00
IUUC-Pab-097555	Pongo abelii	36.19	3.00e-41	161.00
IUUC-Pop-100033	Populus trichocarpa	86.92	3.00e-140	490.00
IUUC-Pca-100328	Procavia capensis	35.74	1.00e-35	142.00
IUUC-Ppe-101960	Prunus persica	83.27	2.00e-143	501.00
IUUC-Pva-103132	Pteropus vampyrus	25.15	1.00e-11	62.80
IUUC-Rno-104866	Rattus norvegicus	36.19	2.00e-41	161.00
IUUC-Sha-106547	Sarcophilus harrisii	35.02	2.00e-41	161.00
IUUC-Smo-109412	Selaginella moellendorffii	81.35	1.00e-152	531.00
IUUC-Sit-110245	Setaria italica	83.33	1.00e-135	475.00
IUUC-Sly-111259	Solanum lycopersicum	85.27	3.00e-137	480.00
IUUC-Stu-112474	Solanum tuberosum	85.98	1.00e-139	488.00
IUUC-Sbi-114035	Sorghum bicolor	83.33	2.00e-136	478.00
IUUC-Ssc-116441	Sus scrofa	36.14	6.00e-38	150.00
IUUC-Tgu-116579	Taeniopygia guttata	36.19	3.00e-41	161.00
IUUC-Tru-118250	Takifugu rubripes	35.07	3.00e-39	154.00
IUUC-Tsy-119548	Tarsius syrichta	26.50	3.00e-07	47.80
IUUC-Tni-120488	Tetraodon nigroviridis	36.29	7.00e-39	153.00
IUUC-Tca-121517	Theobroma cacao	87.79	5.00e-142	496.00
IUUC-Tae-123647	Triticum aestivum	67.73	5.00e-125	439.00
IUUC-Tur-126259	Triticum urartu	79.93	3.00e-134	470.00
IUUC-Ttr-129166	Tursiops truncatus	36.18	3.00e-38	151.00
IUUC-Vpa-130799	Vicugna pacos	32.16	6.00e-18	82.80
IUUC-Vvi-131233	Vitis vinifera	75.49	1.00e-137	481.00
IUUC-Xtr-132553	Xenopus tropicalis	36.19	3.00e-41	161.00
IUUC-Xma-133670	Xiphophorus maculatus	35.82	4.00e-41	160.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence