iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026850

Ensembl Protein ID

AAW42150

UniProt Accession

Q5KKS5; Q55VG1; Q5KKS5_CRYNJ

Genbank Protein ID

AAW42150.1

Protein Name

NEDD8 activating enzyme, putative

Genbank Nucleotide ID

AE017343

Gene Name

CNC02000

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNC02000	AAW42150	AAW42150

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.80e-87	290.7	46	226

Active Site

Position(s)	Description	Evidence
210	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 17   ksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlal 117
            +ak+l++GagglGcE+l nL+l+G+  i+v+Dmdt+++snlnrqFLfr+ dvgksKA vaae++ +++p + v++++ +i++  ++  F+++fdv+v++l
   Q: 46   TKAKILVIGAGGLGCEILQNLALSGFNDIHVIDMDTIDISNLNRQFLFREADVGKSKALVAAEFVMKRVPGCTVTPYHGRIQDHPTS--FYSTFDVIVAGL 144
           479************************************************************************************..************ PP
   S: 118  dnrearrkvnrlclna.......rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewa 190
           d+++arr++n  ++++        +pl+++gt+G++Gq+rvi++ +t cy+cs     p + +P+ct+++tp+ +eh+iewa
   Q: 145  DSISARRWINATLVQMaqedeenIKPLVDGGTEGFKGQARVILPTITSCYECSIdmLTPPTAFPICTIANTPRLPEHCIEWA 226
           **********************99******************************888999********************** PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MTAAHIQSYH SDPTRYAAVD NLLHRKGPWT DERFQGGTET ANFLRTKAKI LVIGAGGLGC 60
EILQNLALSG FNDIHVIDMD TIDISNLNRQ FLFREADVGK SKALVAAEFV MKRVPGCTVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACAACAAA ATACTGTTCC GCCACGATTC GTCCGTTGTG CGCGATTTTT GACACTCACC 60
ATGACAGCAG CTCACATACA GTCCTATCAC TCAGATCCAA CCCGCTATGC TGCCGTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

cne:CNC02000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	46.55	1.00e-76	277.00
IUUC-Aml-001578	Ailuropoda melanoleuca	47.76	3.00e-116	409.00
IUUC-Atr-002591	Amborella trichopoda	50.50	8.00e-92	328.00
IUUC-Apl-003671	Anas platyrhynchos	48.83	9.00e-120	421.00
IUUC-Aca-004749	Anolis carolinensis	48.71	1.00e-118	418.00
IUUC-Aly-005747	Arabidopsis lyrata	48.21	3.00e-95	340.00
IUUC-Ath-006623	Arabidopsis thaliana	48.21	9.00e-95	338.00
IUUC-Ago-007934	Ashbya gossypii	45.07	2.00e-75	273.00
IUUC-Acl-008047	Aspergillus clavatus	58.78	9.00e-138	481.00
IUUC-Afl-008615	Aspergillus flavus	48.05	3.00e-90	323.00
IUUC-Afu-008996	Aspergillus fumigatus	54.78	2.00e-125	440.00
IUUC-Ani-009281	Aspergillus nidulans	53.80	3.00e-90	323.00
IUUC-Ang-009539	Aspergillus niger	56.25	1.00e-125	440.00
IUUC-Aor-010151	Aspergillus oryzae	53.60	4.00e-120	422.00
IUUC-Ate-010502	Aspergillus terreus	56.83	5.00e-127	445.00
IUUC-Ame-011837	Astyanax mexicanus	48.94	1.00e-109	387.00
IUUC-Bgr-012068	Blumeria graminis	51.70	1.00e-117	414.00
IUUC-Bta-013003	Bos taurus	48.24	3.00e-117	413.00
IUUC-Bci-013983	Botrytis cinerea	56.46	3.00e-130	456.00
IUUC-Bdi-014429	Brachypodium distachyon	46.84	5.00e-81	292.00
IUUC-Bol-015813	Brassica oleracea	47.70	1.00e-84	304.00
IUUC-Bra-018023	Brassica rapa	47.45	4.00e-84	303.00
IUUC-Cel-018684	Caenorhabditis elegans	48.23	2.00e-108	384.00
IUUC-Cja-019200	Callithrix jacchus	48.24	2.00e-114	404.00
IUUC-Cfa-021038	Canis familiaris	48.24	3.00e-117	413.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	49.88	5.00e-106	375.00
IUUC-Csa-024079	Chlorocebus sabaeus	48.00	6.00e-117	412.00
IUUC-Cho-025052	Choloepus hoffmanni	42.12	1.00e-97	347.00
IUUC-Cin-025113	Ciona intestinalis	46.82	1.00e-106	377.00
IUUC-Csv-026231	Ciona savignyi	46.12	2.00e-108	383.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	56.09	6.00e-129	452.00
IUUC-Cme-027275	Cyanidioschyzon merolae	38.07	3.00e-74	270.00
IUUC-Dre-028751	Danio rerio	47.65	3.00e-108	383.00
IUUC-Dno-029571	Dasypus novemcinctus	48.00	7.00e-117	412.00
IUUC-Dor-030395	Dipodomys ordii	49.41	1.00e-117	414.00
IUUC-Dse-031329	Dothistroma septosporum	54.23	3.00e-126	442.00
IUUC-Dme-031776	Drosophila melanogaster	46.37	6.00e-106	375.00
IUUC-Ete-032894	Echinops telfairi	48.80	6.00e-39	153.00
IUUC-Eca-034389	Equus caballus	48.24	5.00e-117	412.00
IUUC-Eeu-035152	Erinaceus europaeus	45.48	1.00e-88	318.00
IUUC-Fca-036032	Felis catus	48.24	4.00e-117	412.00
IUUC-Fal-037506	Ficedula albicollis	48.71	1.00e-119	421.00
IUUC-Fox-037871	Fusarium oxysporum	58.20	4.00e-115	405.00
IUUC-Fso-038350	Fusarium solani	56.80	3.00e-127	446.00
IUUC-Gmo-039246	Gadus morhua	46.58	1.00e-108	384.00
IUUC-Ggr-039859	Gaeumannomyces graminis	56.43	7.00e-124	435.00
IUUC-Gga-040843	Gallus gallus	47.76	3.00e-114	403.00
IUUC-Gac-042610	Gasterosteus aculeatus	48.58	1.00e-109	387.00
IUUC-Gma-042744	Glycine max	49.22	4.00e-87	313.00
IUUC-Ggo-044788	Gorilla gorilla	48.12	7.00e-116	408.00
IUUC-Hsa-045849	Homo sapiens	48.24	3.00e-117	412.00
IUUC-Hvu-047819	Hordeum vulgare	48.72	8.00e-78	281.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	48.00	4.00e-117	412.00
IUUC-Kpa-049393	Komagataella pastoris	63.09	2.00e-115	407.00
IUUC-Lch-049471	Latimeria chalumnae	47.84	1.00e-107	381.00
IUUC-Lpe-051297	Leersia perrieri	46.88	2.00e-94	337.00
IUUC-Loc-052910	Lepisosteus oculatus	49.64	1.00e-108	384.00
IUUC-Lma-053181	Leptosphaeria maculans	56.64	2.00e-134	470.00
IUUC-Laf-054314	Loxodonta africana	47.91	1.00e-115	407.00
IUUC-Mcc-054870	Macaca mulatta	48.24	3.00e-117	412.00
IUUC-Meu-056574	Macropus eugenii	38.13	6.00e-49	186.00
IUUC-Mor-056919	Magnaporthe oryzae	54.52	1.00e-117	414.00
IUUC-Mpo-057614	Magnaporthe poae	56.90	2.00e-121	426.00
IUUC-Mtr-058110	Medicago truncatula	48.41	2.00e-86	311.00
IUUC-Mla-058949	Melampsora laricipopulina	66.33	1.00e-150	523.00
IUUC-Mga-059455	Meleagris gallopavo	48.94	4.00e-119	419.00
IUUC-Mvi-060270	Microbotryum violaceum	61.98	5.00e-155	538.00
IUUC-Mmr-061155	Microcebus murinus	47.85	1.00e-111	394.00
IUUC-Mdo-062037	Monodelphis domestica	48.24	1.00e-117	414.00
IUUC-Mmu-063670	Mus musculus	48.94	2.00e-117	414.00
IUUC-Mac-064711	Musa acuminata	50.75	3.00e-91	327.00
IUUC-Mpu-066734	Mustela putorius furo	48.24	2.00e-117	414.00
IUUC-Mlu-067068	Myotis lucifugus	48.24	3.00e-117	413.00
IUUC-Nfi-068349	Neosartorya fischeri	55.26	5.00e-127	445.00
IUUC-Ncr-068626	Neurospora crassa	59.64	7.00e-126	441.00
IUUC-Nle-069366	Nomascus leucogenys	53.52	5.00e-112	395.00
IUUC-Ont-072196	Oreochromis niloticus	49.06	1.00e-109	387.00
IUUC-Oan-073511	Ornithorhynchus anatinus	47.06	3.00e-114	403.00
IUUC-Ocu-073773	Oryctolagus cuniculus	48.47	2.00e-117	413.00
IUUC-Oba-075726	Oryza barthii	42.66	1.00e-79	288.00
IUUC-Obr-076286	Oryza brachyantha	46.35	4.00e-91	326.00
IUUC-Ogu-078473	Oryza glumaepatula	42.66	1.00e-79	288.00
IUUC-Oin-079393	Oryza indica	47.70	7.00e-93	332.00
IUUC-Olo-080446	Oryza longistaminata	44.14	2.00e-83	300.00
IUUC-Ome-081737	Oryza meridionalis	45.11	6.00e-83	299.00
IUUC-Oni-082853	Oryza nivara	42.66	1.00e-79	288.00
IUUC-Opu-083590	Oryza punctata	46.63	2.00e-93	334.00
IUUC-Oru-084184	Oryza rufipogon	42.66	1.00e-79	288.00
IUUC-Osa-085402	Oryza sativa	47.70	7.00e-93	332.00
IUUC-Ola-086671	Oryzias latipes	51.64	6.00e-98	348.00
IUUC-Olu-087738	Ostreococcus lucimarinus	49.87	1.00e-89	321.00
IUUC-Oga-088101	Otolemur garnettii	48.47	8.00e-117	411.00
IUUC-Oar-090293	Ovis aries	47.91	6.00e-116	409.00
IUUC-Ptr-090503	Pan troglodytes	48.24	3.00e-117	412.00
IUUC-Pan-092477	Papio anubis	49.37	7.00e-112	395.00
IUUC-Psi-093442	Pelodiscus sinensis	48.94	2.00e-118	417.00
IUUC-Pma-094247	Petromyzon marinus	49.41	9.00e-111	391.00
IUUC-Pno-094780	Phaeosphaeria nodorum	56.54	2.00e-130	456.00
IUUC-Ppa-095338	Physcomitrella patens	49.14	5.00e-112	395.00
IUUC-Pfo-097137	Poecilia formosa	47.94	1.00e-109	388.00
IUUC-Pab-098060	Pongo abelii	48.00	2.00e-108	384.00
IUUC-Pop-099470	Populus trichocarpa	48.58	1.00e-94	338.00
IUUC-Pca-100500	Procavia capensis	42.86	7.00e-78	282.00
IUUC-Ppe-102008	Prunus persica	48.99	6.00e-86	309.00
IUUC-Pva-103095	Pteropus vampyrus	57.73	4.00e-63	233.00
IUUC-Pgr-103666	Puccinia graminis	64.83	6.00e-156	541.00
IUUC-Ptt-103901	Puccinia triticina	64.07	1.00e-157	547.00
IUUC-Pte-104198	Pyrenophora teres	56.91	7.00e-136	474.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	56.44	3.00e-133	466.00
IUUC-Rno-105446	Rattus norvegicus	48.94	1.00e-117	414.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.52	2.00e-70	257.00
IUUC-Sha-106664	Sarcophilus harrisii	48.24	2.00e-117	414.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	48.10	2.00e-113	400.00
IUUC-Spo-108345	Schizosaccharomyces pombe	50.59	1.00e-121	427.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	54.07	4.00e-118	416.00
IUUC-Smo-109133	Selaginella moellendorffii	47.27	2.00e-110	390.00
IUUC-Sit-109724	Setaria italica	46.88	1.00e-85	308.00
IUUC-Sly-110916	Solanum lycopersicum	48.28	5.00e-95	339.00
IUUC-Stu-112236	Solanum tuberosum	48.28	1.00e-95	341.00
IUUC-Sar-113044	Sorex araneus	48.87	6.00e-111	392.00
IUUC-Sbi-114276	Sorghum bicolor	47.26	1.00e-85	308.00
IUUC-Sre-114963	Sporisorium reilianum	66.18	8.00e-158	547.00
IUUC-Ssc-116301	Sus scrofa	47.91	7.00e-116	408.00
IUUC-Tgu-117265	Taeniopygia guttata	48.71	2.00e-119	420.00
IUUC-Tru-117526	Takifugu rubripes	49.30	5.00e-111	392.00
IUUC-Tsy-119483	Tarsius syrichta	49.03	4.00e-115	406.00
IUUC-Tni-120363	Tetraodon nigroviridis	49.65	1.00e-112	398.00
IUUC-Tca-121731	Theobroma cacao	48.99	1.00e-90	324.00
IUUC-Tre-122221	Trichoderma reesei	56.56	1.00e-113	400.00
IUUC-Tvi-122352	Trichoderma virens	54.14	4.00e-124	436.00
IUUC-Tae-123864	Triticum aestivum	46.10	5.00e-83	300.00
IUUC-Tur-126070	Triticum urartu	44.34	2.00e-66	244.00
IUUC-Tme-127199	Tuber melanosporum	63.47	9.00e-140	488.00
IUUC-Tbe-128076	Tupaia belangeri	48.47	3.00e-117	413.00
IUUC-Ttr-128695	Tursiops truncatus	60.84	4.00e-48	183.00
IUUC-Uma-129638	Ustilago maydis	64.66	5.00e-157	545.00
IUUC-Vda-129963	Verticillium dahliae	56.45	2.00e-119	420.00
IUUC-Vpa-130637	Vicugna pacos	43.63	4.00e-99	352.00
IUUC-Vvi-131613	Vitis vinifera	49.35	2.00e-86	310.00
IUUC-Xtr-132924	Xenopus tropicalis	47.89	1.00e-107	381.00
IUUC-Xma-133356	Xiphophorus maculatus	48.17	1.00e-110	391.00
IUUC-Yli-134365	Yarrowia lipolytica	62.47	2.00e-132	463.00
IUUC-Zma-135941	Zea mays	43.33	1.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence