iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068626

Ensembl Protein ID

ESA43901

UniProt Accession

V5IRG0; V5IRG0_NEUCR

Genbank Protein ID

ESA43901.1

Protein Name

NEDD8-activating enzyme E1 catalytic subunit

Genbank Nucleotide ID

CM002236

Gene Name

NCU02532

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU02532	ESA43901	ESA43901

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.00e-86	289.8	36	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 9    GeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkk 109
           G++  e++ + k+l++GagglGcE+lKnL+l+G++ i v+Dmdt+++snlnrqFLfr  dvgk KAevaa+++ +++  v++++++++i++ +e+  F+++
   Q: 36   GSTVVENMNKIKILVIGAGGLGCEILKNLALSGFKDISVIDMDTIDISNLNRQFLFRHADVGKFKAEVAAKFVERRVKGVKITPYNCKIQDFDED--FYQQ 134
           66677999***************************************************************************************..**** PP
   S: 110  fdvVvlaldnrearrkvnrlclna........rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewavlf 193
           f++Vv++ld++earr++n  ++n+         +pli++gt+G++Gq+rvi++ +  c++c+     p+  +P+ctl++ p+++eh+iewa+++
   Q: 135  FQIVVCGLDSIEARRWINATLVNMascenpdsMKPLIDGGTEGFKGQARVILPTMGSCIECQLdmHAPRAAVPLCTLASIPRQPEHCIEWAHVI 228
           ***************************************************************999*************************443 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MSSPEVLPDS EAKRWKYLNN VRTRPGAFVD PEEFDGSTVV ENMNKIKILV IGAGGLGCEI 60
LKNLALSGFK DISVIDMDTI DISNLNRQFL FRHADVGKFK AEVAAKFVER RVKGVKITPY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACTATGGA AGCTTCCCTC CTCCAGTTCC GTTTGTTTGT TGTCCCGTCA ACTCACCCCT 60
CGGATTGTAC ATTCAACCTG CAACAATTTG TGAGCCGCGA CTAATCAGCA AATATTATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	49.42	4.00e-83	299.00
IUUC-Aml-001578	Ailuropoda melanoleuca	51.95	3.00e-127	446.00
IUUC-Atr-002591	Amborella trichopoda	48.89	9.00e-90	322.00
IUUC-Apl-003671	Anas platyrhynchos	53.57	5.00e-130	455.00
IUUC-Aca-004749	Anolis carolinensis	52.03	1.00e-126	444.00
IUUC-Aly-005747	Arabidopsis lyrata	48.07	3.00e-99	353.00
IUUC-Ath-006623	Arabidopsis thaliana	47.83	4.00e-98	349.00
IUUC-Ago-007934	Ashbya gossypii	40.26	4.00e-66	243.00
IUUC-Acl-008047	Aspergillus clavatus	65.80	1.00e-163	567.00
IUUC-Afl-008615	Aspergillus flavus	55.93	4.00e-108	382.00
IUUC-Afu-008996	Aspergillus fumigatus	65.34	1.00e-156	543.00
IUUC-Ani-009281	Aspergillus nidulans	58.96	5.00e-126	442.00
IUUC-Ang-009539	Aspergillus niger	67.06	2.00e-152	530.00
IUUC-Aor-010151	Aspergillus oryzae	63.93	3.00e-148	516.00
IUUC-Ate-010502	Aspergillus terreus	66.98	1.00e-154	537.00
IUUC-Ame-011837	Astyanax mexicanus	52.89	2.00e-121	427.00
IUUC-Bgr-012068	Blumeria graminis	64.16	3.00e-165	572.00
IUUC-Bta-013003	Bos taurus	53.33	3.00e-128	450.00
IUUC-Bci-013983	Botrytis cinerea	70.99	2.00e-174	603.00
IUUC-Bdi-014429	Brachypodium distachyon	46.95	8.00e-88	315.00
IUUC-Bol-015490	Brassica oleracea	45.23	8.00e-88	315.00
IUUC-Bra-018023	Brassica rapa	44.83	7.00e-87	312.00
IUUC-Cel-018684	Caenorhabditis elegans	45.95	8.00e-106	375.00
IUUC-Cja-019200	Callithrix jacchus	53.32	2.00e-125	440.00
IUUC-Cfa-021038	Canis familiaris	53.33	3.00e-128	449.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	46.63	5.00e-100	355.00
IUUC-Csa-024079	Chlorocebus sabaeus	53.10	7.00e-128	448.00
IUUC-Cho-025052	Choloepus hoffmanni	46.90	3.00e-111	393.00
IUUC-Cin-025113	Ciona intestinalis	50.36	3.00e-115	406.00
IUUC-Csv-026231	Ciona savignyi	48.38	5.00e-121	426.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	72.30	0.00e+00	630.00
IUUC-Cne-026850	Cryptococcus neoformans	58.03	8.00e-130	454.00
IUUC-Cme-027275	Cyanidioschyzon merolae	36.48	2.00e-70	258.00
IUUC-Dre-028751	Danio rerio	52.76	9.00e-121	425.00
IUUC-Dno-029571	Dasypus novemcinctus	52.86	7.00e-128	448.00
IUUC-Dor-030395	Dipodomys ordii	53.11	9.00e-124	434.00
IUUC-Dse-031329	Dothistroma septosporum	62.10	4.00e-147	512.00
IUUC-Dme-031776	Drosophila melanogaster	51.52	1.00e-112	398.00
IUUC-Ete-032894	Echinops telfairi	48.48	1.00e-37	149.00
IUUC-Eca-034389	Equus caballus	53.33	3.00e-128	449.00
IUUC-Eeu-035152	Erinaceus europaeus	47.56	8.00e-99	352.00
IUUC-Fca-036032	Felis catus	53.10	4.00e-128	449.00
IUUC-Fal-037506	Ficedula albicollis	52.51	1.00e-128	451.00
IUUC-Fox-037871	Fusarium oxysporum	76.49	2.00e-163	566.00
IUUC-Fso-038350	Fusarium solani	73.77	0.00e+00	628.00
IUUC-Gmo-039647	Gadus morhua	51.79	3.00e-119	420.00
IUUC-Ggr-039859	Gaeumannomyces graminis	71.72	0.00e+00	640.00
IUUC-Gga-040843	Gallus gallus	50.60	5.00e-121	425.00
IUUC-Gac-042601	Gasterosteus aculeatus	52.18	1.00e-119	421.00
IUUC-Gma-043031	Glycine max	48.63	8.00e-91	325.00
IUUC-Ggo-044788	Gorilla gorilla	53.21	1.00e-126	444.00
IUUC-Hsa-045849	Homo sapiens	53.33	4.00e-128	449.00
IUUC-Hvu-047819	Hordeum vulgare	50.42	6.00e-80	288.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	52.86	8.00e-128	448.00
IUUC-Kpa-049393	Komagataella pastoris	62.79	1.00e-106	377.00
IUUC-Lch-049471	Latimeria chalumnae	52.62	2.00e-120	424.00
IUUC-Lpe-051297	Leersia perrieri	47.32	2.00e-101	360.00
IUUC-Loc-052910	Lepisosteus oculatus	53.55	3.00e-121	426.00
IUUC-Lma-053181	Leptosphaeria maculans	71.43	1.00e-167	580.00
IUUC-Laf-054314	Loxodonta africana	52.94	6.00e-127	445.00
IUUC-Mcc-054870	Macaca mulatta	53.33	3.00e-128	449.00
IUUC-Meu-056574	Macropus eugenii	45.31	6.00e-67	246.00
IUUC-Mor-056919	Magnaporthe oryzae	70.66	0.00e+00	627.00
IUUC-Mpo-057614	Magnaporthe poae	73.93	8.00e-179	617.00
IUUC-Mtr-058110	Medicago truncatula	49.72	1.00e-88	318.00
IUUC-Mla-058949	Melampsora laricipopulina	56.40	5.00e-125	439.00
IUUC-Mga-059455	Meleagris gallopavo	52.98	2.00e-129	453.00
IUUC-Mvi-060270	Microbotryum violaceum	55.68	3.00e-132	462.00
IUUC-Mmr-061155	Microcebus murinus	54.76	5.00e-124	435.00
IUUC-Mdo-062037	Monodelphis domestica	53.33	5.00e-128	449.00
IUUC-Mmu-063670	Mus musculus	53.33	7.00e-128	448.00
IUUC-Mac-064711	Musa acuminata	49.88	5.00e-92	329.00
IUUC-Mpu-066734	Mustela putorius furo	53.08	1.00e-127	447.00
IUUC-Mlu-067068	Myotis lucifugus	53.33	6.00e-128	449.00
IUUC-Nfi-068349	Neosartorya fischeri	65.34	2.00e-156	543.00
IUUC-Nle-069366	Nomascus leucogenys	48.94	2.00e-112	397.00
IUUC-Opr-070993	Ochotona princeps	52.24	7.00e-37	146.00
IUUC-Ont-072196	Oreochromis niloticus	53.35	3.00e-120	423.00
IUUC-Oan-073511	Ornithorhynchus anatinus	52.03	3.00e-127	446.00
IUUC-Ocu-073773	Oryctolagus cuniculus	53.57	5.00e-128	449.00
IUUC-Oba-075726	Oryza barthii	44.18	6.00e-88	315.00
IUUC-Obr-076286	Oryza brachyantha	46.34	5.00e-97	346.00
IUUC-Ogu-078473	Oryza glumaepatula	44.18	5.00e-88	316.00
IUUC-Oin-079393	Oryza indica	47.55	2.00e-100	357.00
IUUC-Olo-080446	Oryza longistaminata	45.34	5.00e-93	332.00
IUUC-Ome-081737	Oryza meridionalis	45.59	7.00e-91	325.00
IUUC-Oni-082853	Oryza nivara	44.18	6.00e-88	315.00
IUUC-Opu-083590	Oryza punctata	47.06	6.00e-101	358.00
IUUC-Oru-084184	Oryza rufipogon	44.18	6.00e-88	315.00
IUUC-Osa-085402	Oryza sativa	47.55	2.00e-100	357.00
IUUC-Ola-086671	Oryzias latipes	51.30	6.00e-100	355.00
IUUC-Olu-087738	Ostreococcus lucimarinus	46.12	4.00e-84	303.00
IUUC-Oga-088101	Otolemur garnettii	53.33	2.00e-127	447.00
IUUC-Oar-090293	Ovis aries	52.94	6.00e-127	445.00
IUUC-Ptr-090503	Pan troglodytes	53.33	4.00e-128	449.00
IUUC-Pan-092477	Papio anubis	51.90	1.00e-122	431.00
IUUC-Psi-093442	Pelodiscus sinensis	52.51	4.00e-126	442.00
IUUC-Pma-094247	Petromyzon marinus	52.63	2.00e-121	427.00
IUUC-Pno-094780	Phaeosphaeria nodorum	71.12	2.00e-163	566.00
IUUC-Ppa-095961	Physcomitrella patens	49.64	2.00e-115	407.00
IUUC-Pfo-097137	Poecilia formosa	52.66	7.00e-122	428.00
IUUC-Pab-098060	Pongo abelii	53.10	7.00e-120	422.00
IUUC-Pop-099914	Populus trichocarpa	50.51	3.00e-98	350.00
IUUC-Pca-100500	Procavia capensis	49.00	1.00e-92	331.00
IUUC-Ppe-102008	Prunus persica	50.28	2.00e-88	317.00
IUUC-Pva-103095	Pteropus vampyrus	58.16	6.00e-62	229.00
IUUC-Pgr-103666	Puccinia graminis	56.59	2.00e-129	453.00
IUUC-Ptt-103901	Puccinia triticina	56.46	2.00e-130	457.00
IUUC-Pte-104198	Pyrenophora teres	71.19	2.00e-167	580.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	69.98	7.00e-163	564.00
IUUC-Rno-105446	Rattus norvegicus	53.33	1.00e-127	447.00
IUUC-Sce-106355	Saccharomyces cerevisiae	39.40	2.00e-63	233.00
IUUC-Sha-106664	Sarcophilus harrisii	53.57	9.00e-129	451.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	47.36	4.00e-107	379.00
IUUC-Spo-108345	Schizosaccharomyces pombe	44.49	2.00e-105	374.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	67.45	2.00e-157	546.00
IUUC-Smo-109098	Selaginella moellendorffii	48.42	3.00e-115	406.00
IUUC-Sit-109724	Setaria italica	47.24	4.00e-91	326.00
IUUC-Sly-110916	Solanum lycopersicum	48.28	3.00e-96	343.00
IUUC-Stu-112236	Solanum tuberosum	48.28	3.00e-96	343.00
IUUC-Sar-113044	Sorex araneus	54.50	4.00e-124	436.00
IUUC-Sbi-114276	Sorghum bicolor	47.24	3.00e-91	327.00
IUUC-Sre-114963	Sporisorium reilianum	58.25	4.00e-136	475.00
IUUC-Ssc-116301	Sus scrofa	52.94	1.00e-126	444.00
IUUC-Tgu-117265	Taeniopygia guttata	52.51	1.00e-128	451.00
IUUC-Tru-117526	Takifugu rubripes	52.42	6.00e-117	412.00
IUUC-Tsy-119483	Tarsius syrichta	55.53	4.00e-126	442.00
IUUC-Tni-120363	Tetraodon nigroviridis	52.78	6.00e-119	419.00
IUUC-Tca-121731	Theobroma cacao	49.62	8.00e-90	322.00
IUUC-Tre-122221	Trichoderma reesei	74.86	2.00e-161	560.00
IUUC-Tvi-122352	Trichoderma virens	71.59	3.00e-180	622.00
IUUC-Tae-123864	Triticum aestivum	49.39	9.00e-91	325.00
IUUC-Tur-126070	Triticum urartu	47.13	2.00e-72	264.00
IUUC-Tme-127199	Tuber melanosporum	64.30	1.00e-139	487.00
IUUC-Tbe-128076	Tupaia belangeri	53.33	8.00e-128	448.00
IUUC-Ttr-128695	Tursiops truncatus	42.53	1.00e-49	188.00
IUUC-Uma-129638	Ustilago maydis	57.92	4.00e-135	472.00
IUUC-Vda-129963	Verticillium dahliae	71.98	3.00e-171	592.00
IUUC-Vpa-130637	Vicugna pacos	47.49	9.00e-108	381.00
IUUC-Vvi-131613	Vitis vinifera	49.72	2.00e-87	314.00
IUUC-Xtr-132924	Xenopus tropicalis	51.26	1.00e-116	411.00
IUUC-Xma-133356	Xiphophorus maculatus	52.66	1.00e-121	427.00
IUUC-Yli-134365	Yarrowia lipolytica	59.06	4.00e-126	442.00
IUUC-Zma-135941	Zea mays	44.35	1.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence