iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-086437

Ensembl Protein ID

ENSORLP00000023064.1

UniProt Accession

H2MW48; H2MW48_ORYLA

Protein Name

Uncharacterized protein

Gene Name

llgl2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000018426.1	ENSORLT00000023065.1	ENSORLP00000023064.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-06	27.4	431	448

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 13   d.tllvsGsdDgtikvWD 29
             +ll++G  Dgt++ WD
   Q: 431  QrDLLLTGHEDGTVRFWD 448
           4578************** PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MKRFRRTPDS QRDRIKQELF QFSKTVEHGF PHQPSALGHS SSLQLLAIGT RSGAIKLYGA 60
PGVEFMGLHD ENAAVTQVHF LPHQVELVTL LDDNSLHMWT LKGHKGVSEL LEIGRFVLTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAGAT TCAGAAGGAC TCCCGACTCC CAGAGAGACC GGATCAAACA GGAGCTCTTC 60
CAGTTCAGCA AGGCAAGTCC TGAACAAAAG ACATGCCTCA CCTGAACAGG TGCAGAGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08366--LLGL

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0031581--P:hemidesmosome assembly
GO:0070121--P:Kupffer's vesicle development
GO:0044458--P:motile cilium assembly
GO:0030336--P:negative regulation of cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0048919--P:posterior lateral line neuromast development
GO:0045682--P:regulation of epidermis development
GO:0098773--P:skin epidermis development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002413	Ailuropoda melanoleuca	65.87	0.00e+00	1237.00
IUUC-Apl-003619	Anas platyrhynchos	66.20	0.00e+00	1248.00
IUUC-Bta-013249	Bos taurus	65.97	0.00e+00	1241.00
IUUC-Cfa-020305	Canis familiaris	66.97	0.00e+00	1238.00
IUUC-Cpo-021354	Cavia porcellus	64.19	0.00e+00	1216.00
IUUC-Csa-024027	Chlorocebus sabaeus	65.04	0.00e+00	1236.00
IUUC-Dno-028910	Dasypus novemcinctus	64.64	0.00e+00	1206.00
IUUC-Dor-030976	Dipodomys ordii	63.01	0.00e+00	1159.00
IUUC-Ete-032938	Echinops telfairi	59.80	0.00e+00	658.00
IUUC-Eeu-035274	Erinaceus europaeus	66.11	0.00e+00	1148.00
IUUC-Fca-036585	Felis catus	66.24	0.00e+00	1227.00
IUUC-Fal-037603	Ficedula albicollis	65.91	0.00e+00	1246.00
IUUC-Gga-040222	Gallus gallus	65.51	0.00e+00	1232.00
IUUC-Ggo-045203	Gorilla gorilla	64.64	0.00e+00	1219.00
IUUC-Hsa-045870	Homo sapiens	66.24	0.00e+00	1243.00
IUUC-Lch-049973	Latimeria chalumnae	66.34	0.00e+00	1288.00
IUUC-Laf-053899	Loxodonta africana	66.37	0.00e+00	1239.00
IUUC-Mcc-055790	Macaca mulatta	65.14	0.00e+00	1235.00
IUUC-Mpo-057585	Magnaporthe poae	21.40	4.00e-10	60.50
IUUC-Mga-059850	Meleagris gallopavo	65.27	0.00e+00	1200.00
IUUC-Mmr-060930	Microcebus murinus	64.78	0.00e+00	1170.00
IUUC-Mdo-062588	Monodelphis domestica	64.90	0.00e+00	1261.00
IUUC-Mpu-065729	Mustela putorius furo	66.04	0.00e+00	1248.00
IUUC-Mlu-066984	Myotis lucifugus	65.88	0.00e+00	1239.00
IUUC-Nle-069136	Nomascus leucogenys	64.25	0.00e+00	1206.00
IUUC-Oan-073438	Ornithorhynchus anatinus	61.13	0.00e+00	1006.00
IUUC-Ocu-074863	Oryctolagus cuniculus	64.37	0.00e+00	1196.00
IUUC-Oba-075180	Oryza barthii	20.30	2.00e-10	61.60
IUUC-Ogu-079037	Oryza glumaepatula	20.00	5.00e-10	60.50
IUUC-Oin-079192	Oryza indica	20.30	2.00e-10	61.60
IUUC-Olo-080693	Oryza longistaminata	21.02	7.00e-12	66.20
IUUC-Oni-082885	Oryza nivara	20.30	1.00e-10	62.00
IUUC-Oru-084893	Oryza rufipogon	21.09	1.00e-12	68.60
IUUC-Osa-085916	Oryza sativa	20.11	2.00e-09	58.20
IUUC-Oga-088270	Otolemur garnettii	66.10	0.00e+00	1229.00
IUUC-Ptr-091452	Pan troglodytes	65.12	0.00e+00	1224.00
IUUC-Pan-092654	Papio anubis	65.24	0.00e+00	1239.00
IUUC-Psi-093341	Pelodiscus sinensis	65.44	0.00e+00	1252.00
IUUC-Pva-102373	Pteropus vampyrus	66.07	0.00e+00	1242.00
IUUC-Rno-104988	Rattus norvegicus	65.51	0.00e+00	1229.00
IUUC-Sha-106592	Sarcophilus harrisii	63.40	0.00e+00	1176.00
IUUC-Tgu-117381	Taeniopygia guttata	66.00	0.00e+00	1245.00
IUUC-Tca-121612	Theobroma cacao	20.45	4.00e-13	70.90
IUUC-Tbe-127984	Tupaia belangeri	59.74	2.00e-172	599.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence