iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067704

Ensembl Protein ID

ENSMLUP00000002843.2

UniProt Accession

G1NZF5; G1NZF5_MYOLU

Genbank Protein ID

ENSMLUP00000002843

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02059724

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003133.2	ENSMLUT00000003129.2	ENSMLUP00000002843.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-12	47.6	497	546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 497  VALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 546
           69***********************..9*********..9************97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MWKASAGHAV SISQDDGGAD DWETDPDFEN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVYQEHRSLK EKELATGPRA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGG CTTCGGCGGG CCACGCCGTG TCCATCAGCC AGGACGACGG CGGTGCCGAC 60
GACTGGGAAA CGGACCCCGA TTTCGAGGTG AGTCCCCGCT CCACCCCGCT TCCTTGTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	83.94	0.00e+00	841.00
IUUC-Apl-003745	Anas platyrhynchos	77.24	0.00e+00	706.00
IUUC-Aca-004438	Anolis carolinensis	74.07	0.00e+00	777.00
IUUC-Ame-011504	Astyanax mexicanus	54.55	6.00e-95	341.00
IUUC-Bta-013563	Bos taurus	82.88	0.00e+00	806.00
IUUC-Bci-013690	Botrytis cinerea	56.60	3.00e-12	67.40
IUUC-Cfa-020718	Canis familiaris	80.55	0.00e+00	833.00
IUUC-Cpo-022303	Cavia porcellus	80.40	0.00e+00	870.00
IUUC-Csa-023431	Chlorocebus sabaeus	84.21	0.00e+00	834.00
IUUC-Cin-025677	Ciona intestinalis	57.23	4.00e-104	372.00
IUUC-Csv-026140	Ciona savignyi	59.14	3.00e-94	339.00
IUUC-Dre-028012	Danio rerio	73.06	4.00e-147	514.00
IUUC-Dno-029332	Dasypus novemcinctus	79.71	0.00e+00	758.00
IUUC-Dse-031182	Dothistroma septosporum	51.79	4.00e-10	60.10
IUUC-Dme-031931	Drosophila melanogaster	62.17	8.00e-73	268.00
IUUC-Eca-033801	Equus caballus	87.07	0.00e+00	859.00
IUUC-Fca-035633	Felis catus	82.66	0.00e+00	689.00
IUUC-Fal-036775	Ficedula albicollis	76.44	0.00e+00	687.00
IUUC-Fox-037778	Fusarium oxysporum	61.40	6.00e-15	76.30
IUUC-Fso-038435	Fusarium solani	58.82	2.00e-12	67.80
IUUC-Gmo-038507	Gadus morhua	61.33	4.00e-21	95.90
IUUC-Gga-040568	Gallus gallus	77.30	0.00e+00	731.00
IUUC-Gac-042253	Gasterosteus aculeatus	55.83	7.00e-114	404.00
IUUC-Hsa-046818	Homo sapiens	84.57	0.00e+00	839.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	82.18	0.00e+00	803.00
IUUC-Lch-050199	Latimeria chalumnae	63.43	2.00e-122	432.00
IUUC-Loc-052855	Lepisosteus oculatus	73.46	3.00e-149	521.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	2.00e-12	67.80
IUUC-Laf-053866	Loxodonta africana	83.36	0.00e+00	891.00
IUUC-Mcc-055515	Macaca mulatta	84.75	0.00e+00	842.00
IUUC-Mor-057105	Magnaporthe oryzae	54.90	3.00e-11	63.90
IUUC-Mga-059791	Meleagris gallopavo	74.00	0.00e+00	727.00
IUUC-Mmr-061147	Microcebus murinus	84.63	0.00e+00	787.00
IUUC-Mdo-062660	Monodelphis domestica	60.14	5.00e-169	588.00
IUUC-Mmu-064023	Mus musculus	82.51	0.00e+00	816.00
IUUC-Mpu-065867	Mustela putorius furo	80.11	0.00e+00	772.00
IUUC-Ont-071873	Oreochromis niloticus	74.30	1.00e-148	520.00
IUUC-Oan-073528	Ornithorhynchus anatinus	73.63	2.00e-141	495.00
IUUC-Oga-088028	Otolemur garnettii	82.58	0.00e+00	818.00
IUUC-Oar-090203	Ovis aries	82.95	0.00e+00	738.00
IUUC-Pan-092594	Papio anubis	84.53	0.00e+00	837.00
IUUC-Psi-093389	Pelodiscus sinensis	76.15	0.00e+00	736.00
IUUC-Pma-094161	Petromyzon marinus	41.96	4.00e-79	288.00
IUUC-Pno-095096	Phaeosphaeria nodorum	58.18	1.00e-13	72.40
IUUC-Pfo-097391	Poecilia formosa	54.17	4.00e-110	391.00
IUUC-Pab-097913	Pongo abelii	82.40	0.00e+00	807.00
IUUC-Pgr-103652	Puccinia graminis	47.37	9.00e-10	58.90
IUUC-Rno-105489	Rattus norvegicus	81.60	0.00e+00	788.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	7.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	67.86	0.00e+00	655.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	75.77	0.00e+00	699.00
IUUC-Tru-118718	Takifugu rubripes	72.33	2.00e-151	529.00
IUUC-Tni-120535	Tetraodon nigroviridis	72.85	2.00e-145	508.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.50
IUUC-Tvi-122614	Trichoderma virens	59.18	8.00e-12	65.90
IUUC-Vda-129766	Verticillium dahliae	57.89	9.00e-14	72.40
IUUC-Xtr-131797	Xenopus tropicalis	69.08	4.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence