iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134364

Ensembl Protein ID

CAG82294

UniProt Accession

Q6CBI8; CIAO1_YARLI

Genbank Protein ID

CAG82294.1

Protein Name

Probable cytosolic iron-sulfur protein assembly protein 1

Genbank Nucleotide ID

CR382129

Gene Name

CIA1; YALI0C18381g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_C18381g	CAG82294	CAG82294

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-40	133.3	188	221
UBD/Beta-Prp	1.60e-46	157.2	68	331

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvWD 29
           gH++ v+++af     sd +lvs+sdD+t+ vW 
   Q: 188  GHESTVWGCAFepsegSDLRLVSCSDDKTCIVWK 221
           8************9988888*************7 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsgdklvsGshdr 116
           ++ la gs d+t+ +w  ++     l+ ++ghe+ev+ v++s dg++l+t+s+D+ i vw+ +     ++c+++l+ h+++v  ++++ps  +++s+s d+
   Q: 68   SPSLALGSFDSTVSIWGKEDDEWqfLAAIEGHENEVKGVSWSCDGQLLATCSRDKSIWVWEADdmndEFECISVLQDHTQDVKHVAWHPSEMVFASASYDD 168
           567999**********998755445***********************************55555589********************************* PP
   S: 117  tirvwdletgqclee.tlsghdgvvncvvvhpdg...nllvsGslDrtvrlWdl.................ktgkllrtl......tgghtdsvyslsfds 190
           t+r+w  + + ++    l gh+++v++ ++ p++     lvs+s+D+t+ +W+                  + + l +++       ++ht+++ys+++++
   Q: 169  TVRLWREDDDDWICVaDLGGHESTVWGCAFEPSEgsdLRLVSCSDDKTCIVWKKegqvggtgdhsgirpafRADPLSEEWiqqatlPEAHTRAIYSVAWNK 269
           *****87777665433799**********99876533589*******************************888888888888888556************ PP
   S: 191  ngkelvsgsldgtvklwdlq......tgecvrtlnght..dnvksvrfspnderlvsgssDgsiriWd 250
           ng +++s + dg++ ++               ++++      v++v  +  d+ lv+ ++Dg+++iW 
   Q: 270  NG-RIASTGADGKLVVYKENgpgqwvV---ESEVENAHgvYEVNDVVWL--DDKLVTSGDDGVVNIWE 331
           *8.9999999*******9988653321...2222222234788888888..88899999********5 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MQLIKALKGH TDRAWAASVH PNLPLLATCS GDKTVRIYNT NNWELVTTIT EGHNRSVRSV 60
AWKPSGSSPS LALGSFDSTV SIWGKEDDEW QFLAAIEGHE NEVKGVSWSC DGQLLATCSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTGA TCAAGGCACT GAAAGGACAC ACGGACCGGG CGTGGGCAGC GTCCGTCCAC 60
CCCAACCTGC CTCTTCTGGC CACGTGCTCG GGCGACAAAA CTGTGCGAAT CTACAACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR023294--Tachylectin2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0005634--C:nucleus
GO:0016226--P:iron-sulfur cluster assembly
GO:0002098--P:tRNA wobble uridine modification

KEGG

yli:YALI0C18381g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	42.49	2.00e-48	185.00
IUUC-Aml-001317	Ailuropoda melanoleuca	43.10	6.00e-60	222.00
IUUC-Atr-003029	Amborella trichopoda	42.18	6.00e-67	245.00
IUUC-Apl-004042	Anas platyrhynchos	41.91	2.00e-20	88.60
IUUC-Aly-006458	Arabidopsis lyrata	38.76	1.00e-58	218.00
IUUC-Ath-006671	Arabidopsis thaliana	39.61	2.00e-59	220.00
IUUC-Ago-007820	Ashbya gossypii	51.61	1.00e-89	320.00
IUUC-Acl-008042	Aspergillus clavatus	39.21	3.00e-71	259.00
IUUC-Afl-008639	Aspergillus flavus	41.43	2.00e-77	281.00
IUUC-Afu-008899	Aspergillus fumigatus	39.22	5.00e-72	263.00
IUUC-Ani-009453	Aspergillus nidulans	39.81	3.00e-75	273.00
IUUC-Ang-009758	Aspergillus niger	42.08	2.00e-77	280.00
IUUC-Aor-010212	Aspergillus oryzae	41.43	2.00e-77	281.00
IUUC-Ate-010314	Aspergillus terreus	42.29	9.00e-79	285.00
IUUC-Ame-010676	Astyanax mexicanus	44.02	6.00e-71	258.00
IUUC-Bgr-012095	Blumeria graminis	36.92	3.00e-58	217.00
IUUC-Bta-012884	Bos taurus	42.73	3.00e-60	223.00
IUUC-Bci-013622	Botrytis cinerea	37.99	5.00e-59	219.00
IUUC-Bdi-014614	Brachypodium distachyon	40.00	5.00e-60	222.00
IUUC-Bol-016439	Brassica oleracea	41.29	2.00e-60	224.00
IUUC-Bra-016830	Brassica rapa	39.71	3.00e-59	220.00
IUUC-Cel-018709	Caenorhabditis elegans	35.29	2.00e-47	181.00
IUUC-Cja-019822	Callithrix jacchus	43.44	9.00e-61	224.00
IUUC-Cfa-020823	Canis familiaris	43.39	1.00e-60	224.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	40.57	1.00e-61	227.00
IUUC-Csa-023754	Chlorocebus sabaeus	43.15	8.00e-61	225.00
IUUC-Cin-025395	Ciona intestinalis	39.94	1.00e-62	231.00
IUUC-Csv-025943	Ciona savignyi	40.58	2.00e-64	237.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	38.10	2.00e-62	231.00
IUUC-Cne-026939	Cryptococcus neoformans	31.35	2.00e-50	191.00
IUUC-Cme-027239	Cyanidioschyzon merolae	37.32	4.00e-41	160.00
IUUC-Dre-028172	Danio rerio	42.57	2.00e-67	247.00
IUUC-Dno-029472	Dasypus novemcinctus	45.00	2.00e-55	206.00
IUUC-Dor-031134	Dipodomys ordii	37.43	6.00e-44	169.00
IUUC-Dse-031535	Dothistroma septosporum	38.72	5.00e-70	256.00
IUUC-Dme-032020	Drosophila melanogaster	41.74	5.00e-65	239.00
IUUC-Eca-033700	Equus caballus	43.44	1.00e-60	224.00
IUUC-Eeu-035010	Erinaceus europaeus	44.31	6.00e-59	219.00
IUUC-Fca-036309	Felis catus	38.97	8.00e-54	201.00
IUUC-Fal-037243	Ficedula albicollis	53.74	1.00e-51	193.00
IUUC-Fox-038058	Fusarium oxysporum	38.48	2.00e-58	218.00
IUUC-Fso-038459	Fusarium solani	39.06	9.00e-61	225.00
IUUC-Gmo-039375	Gadus morhua	39.65	3.00e-56	210.00
IUUC-Ggr-040002	Gaeumannomyces graminis	37.02	4.00e-62	229.00
IUUC-Gga-040294	Gallus gallus	42.90	1.00e-49	187.00
IUUC-Gac-042499	Gasterosteus aculeatus	40.70	1.00e-53	201.00
IUUC-Gma-043543	Glycine max	41.29	8.00e-65	238.00
IUUC-Ggo-045181	Gorilla gorilla	43.15	8.00e-61	225.00
IUUC-Hsa-046528	Homo sapiens	43.15	8.00e-61	225.00
IUUC-Hvu-047341	Hordeum vulgare	50.79	4.00e-46	175.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	43.44	1.00e-60	224.00
IUUC-Kpa-049353	Komagataella pastoris	50.73	2.00e-97	347.00
IUUC-Lch-049763	Latimeria chalumnae	43.15	2.00e-62	230.00
IUUC-Lpe-051500	Leersia perrieri	36.72	2.00e-54	204.00
IUUC-Loc-052021	Lepisosteus oculatus	43.27	5.00e-59	219.00
IUUC-Lma-053331	Leptosphaeria maculans	39.39	6.00e-74	270.00
IUUC-Laf-054558	Loxodonta africana	43.02	7.00e-60	222.00
IUUC-Mcc-055374	Macaca mulatta	42.82	2.00e-60	223.00
IUUC-Meu-056042	Macropus eugenii	49.12	5.00e-49	185.00
IUUC-Mor-057187	Magnaporthe oryzae	39.09	7.00e-67	245.00
IUUC-Mtr-058072	Medicago truncatula	42.13	6.00e-67	245.00
IUUC-Mla-059108	Melampsora laricipopulina	30.54	1.00e-47	182.00
IUUC-Mga-059370	Meleagris gallopavo	39.10	8.00e-36	141.00
IUUC-Mvi-060495	Microbotryum violaceum	37.99	1.00e-58	218.00
IUUC-Mmr-060902	Microcebus murinus	43.60	6.00e-62	228.00
IUUC-Mdo-062510	Monodelphis domestica	41.69	4.00e-57	212.00
IUUC-Mmu-063575	Mus musculus	43.60	9.00e-61	224.00
IUUC-Mac-065322	Musa acuminata	41.64	5.00e-65	239.00
IUUC-Mpu-065925	Mustela putorius furo	43.39	2.00e-60	224.00
IUUC-Mlu-067755	Myotis lucifugus	43.60	8.00e-62	228.00
IUUC-Nfi-068327	Neosartorya fischeri	39.41	4.00e-75	273.00
IUUC-Ncr-068845	Neurospora crassa	36.01	8.00e-53	199.00
IUUC-Nle-069406	Nomascus leucogenys	41.98	6.00e-57	212.00
IUUC-Opr-070416	Ochotona princeps	48.45	1.00e-31	128.00
IUUC-Ont-071936	Oreochromis niloticus	41.28	1.00e-56	211.00
IUUC-Oan-073452	Ornithorhynchus anatinus	51.41	2.00e-37	146.00
IUUC-Ocu-074791	Oryctolagus cuniculus	43.15	3.00e-61	226.00
IUUC-Oba-075636	Oryza barthii	40.69	3.00e-61	226.00
IUUC-Obr-076742	Oryza brachyantha	40.33	5.00e-53	199.00
IUUC-Ogl-077766	Oryza glaberrima	40.69	3.00e-61	226.00
IUUC-Ogu-079039	Oryza glumaepatula	40.40	2.00e-60	223.00
IUUC-Oin-079315	Oryza indica	40.66	3.00e-53	200.00
IUUC-Olo-080669	Oryza longistaminata	35.88	8.00e-53	199.00
IUUC-Ome-081490	Oryza meridionalis	40.69	2.00e-61	227.00
IUUC-Oni-082572	Oryza nivara	40.69	3.00e-61	226.00
IUUC-Opu-083732	Oryza punctata	40.97	7.00e-62	228.00
IUUC-Oru-084763	Oryza rufipogon	40.69	3.00e-61	226.00
IUUC-Osa-085372	Oryza sativa	40.69	3.00e-61	226.00
IUUC-Ola-087379	Oryzias latipes	39.60	3.00e-55	206.00
IUUC-Olu-087801	Ostreococcus lucimarinus	38.31	4.00e-42	162.00
IUUC-Oga-089076	Otolemur garnettii	44.02	8.00e-61	224.00
IUUC-Oar-090022	Ovis aries	42.86	7.00e-60	221.00
IUUC-Ptr-090809	Pan troglodytes	43.15	8.00e-61	225.00
IUUC-Pan-091685	Papio anubis	43.15	1.00e-60	225.00
IUUC-Psi-093046	Pelodiscus sinensis	43.15	2.00e-59	220.00
IUUC-Pma-094181	Petromyzon marinus	44.19	5.00e-70	255.00
IUUC-Pno-094882	Phaeosphaeria nodorum	39.56	5.00e-74	269.00
IUUC-Ppa-095172	Physcomitrella patens	39.66	8.00e-60	221.00
IUUC-Pfo-096396	Poecilia formosa	40.99	2.00e-57	213.00
IUUC-Pab-098427	Pongo abelii	42.98	4.00e-61	226.00
IUUC-Pop-100016	Populus trichocarpa	42.82	4.00e-65	239.00
IUUC-Pca-101048	Procavia capensis	43.31	2.00e-60	223.00
IUUC-Ppe-102050	Prunus persica	41.00	2.00e-64	237.00
IUUC-Pva-103117	Pteropus vampyrus	43.31	4.00e-60	223.00
IUUC-Pgr-103307	Puccinia graminis	32.80	1.00e-53	202.00
IUUC-Ptt-103938	Puccinia triticina	36.23	3.00e-44	170.00
IUUC-Pte-104315	Pyrenophora teres	39.80	2.00e-75	274.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	39.30	2.00e-75	274.00
IUUC-Rno-105523	Rattus norvegicus	43.60	9.00e-61	224.00
IUUC-Sce-106297	Saccharomyces cerevisiae	49.42	8.00e-84	301.00
IUUC-Sha-106981	Sarcophilus harrisii	41.67	2.00e-50	190.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	45.27	8.00e-81	292.00
IUUC-Spo-108214	Schizosaccharomyces pombe	48.10	2.00e-81	294.00
IUUC-Smo-109034	Selaginella moellendorffii	38.46	9.00e-55	204.00
IUUC-Sit-110663	Setaria italica	40.06	1.00e-59	221.00
IUUC-Sly-110898	Solanum lycopersicum	41.29	2.00e-57	213.00
IUUC-Stu-112647	Solanum tuberosum	42.76	1.00e-53	201.00
IUUC-Sbi-114288	Sorghum bicolor	41.26	3.00e-61	226.00
IUUC-Sre-115065	Sporisorium reilianum	37.60	7.00e-62	229.00
IUUC-Ssc-115960	Sus scrofa	40.99	2.00e-61	227.00
IUUC-Tru-118382	Takifugu rubripes	41.57	3.00e-67	246.00
IUUC-Tsy-119585	Tarsius syrichta	40.18	3.00e-52	196.00
IUUC-Tni-120133	Tetraodon nigroviridis	40.99	2.00e-59	220.00
IUUC-Tca-121167	Theobroma cacao	40.06	1.00e-58	218.00
IUUC-Tre-122119	Trichoderma reesei	36.00	1.00e-58	218.00
IUUC-Tvi-122407	Trichoderma virens	37.95	3.00e-63	233.00
IUUC-Tae-124928	Triticum aestivum	40.69	3.00e-58	216.00
IUUC-Tur-126682	Triticum urartu	42.86	1.00e-48	184.00
IUUC-Tme-127095	Tuber melanosporum	41.36	1.00e-81	294.00
IUUC-Tbe-128004	Tupaia belangeri	43.60	2.00e-61	226.00
IUUC-Ttr-129284	Tursiops truncatus	42.07	5.00e-55	206.00
IUUC-Uma-129527	Ustilago maydis	38.18	2.00e-61	227.00
IUUC-Vda-129854	Verticillium dahliae	37.62	7.00e-60	222.00
IUUC-Vpa-130681	Vicugna pacos	53.39	3.00e-25	106.00
IUUC-Vvi-131004	Vitis vinifera	42.86	2.00e-64	236.00
IUUC-Xtr-131928	Xenopus tropicalis	41.86	5.00e-59	219.00
IUUC-Xma-134290	Xiphophorus maculatus	40.23	3.00e-54	203.00
IUUC-Zma-135658	Zea mays	40.11	4.00e-59	219.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence