iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062850

UUCD1 version

UUC-MoD-00759

Ensembl Protein ID

ENSMODP00000020411.3

UniProt Accession

F7FKY1; F7FKY1_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016334.3	ENSMODT00000020770.3	ENSMODP00000020411.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-06	27.9	401	429
E3 activity/RING/RING	3.80e-09	37.1	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 401  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 429
           99*********9978888887.689*9999 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++      ++  +  +   +CP Cr
   Q: 10   CSICYSIFED-PRVLPCSHTFCRNCLENVlqasgnFYVRRALRIPLTCPNCR 60
           **********.***************999677777666666777777****8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MHNFEEELTC SICYSIFEDP RVLPCSHTFC RNCLENVLQA SGNFYVRRAL RIPLTCPNCR 60
RTVEIPPPGI ESLPINFALR AIIEKYEQEE HSDVITCPEH SSQPLNIYCL QDRQPVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATAATT TTGAGGAGGA ACTTACATGC TCCATTTGTT ATAGCATATT TGAGGATCCT 60
CGAGTCCTGC CATGCTCCCA TACGTTTTGC AGAAATTGTC TGGAAAATGT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0008270--F:zinc ion binding
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0060271--P:cilium assembly
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	96.63	6.00e-175	607.00
IUUC-Apl-003721	Anas platyrhynchos	87.83	0.00e+00	1141.00
IUUC-Aca-004488	Anolis carolinensis	86.69	0.00e+00	1129.00
IUUC-Ame-011402	Astyanax mexicanus	74.86	6.00e-167	580.00
IUUC-Bta-013037	Bos taurus	83.36	0.00e+00	1054.00
IUUC-Cel-018360	Caenorhabditis elegans	39.90	2.00e-152	533.00
IUUC-Cja-019076	Callithrix jacchus	84.12	0.00e+00	1647.00
IUUC-Cfa-020999	Canis familiaris	95.25	0.00e+00	1227.00
IUUC-Cpo-021333	Cavia porcellus	83.98	0.00e+00	1015.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.59	3.00e-157	548.00
IUUC-Csa-023699	Chlorocebus sabaeus	95.13	0.00e+00	1226.00
IUUC-Cho-024904	Choloepus hoffmanni	76.86	1.00e-157	550.00
IUUC-Cin-025399	Ciona intestinalis	58.01	0.00e+00	783.00
IUUC-Csv-026186	Ciona savignyi	56.70	0.00e+00	768.00
IUUC-Dre-028276	Danio rerio	74.68	0.00e+00	1038.00
IUUC-Dno-029824	Dasypus novemcinctus	94.90	0.00e+00	1250.00
IUUC-Dor-031141	Dipodomys ordii	90.65	0.00e+00	1162.00
IUUC-Dme-031620	Drosophila melanogaster	34.62	2.00e-111	396.00
IUUC-Ete-033028	Echinops telfairi	77.13	0.00e+00	809.00
IUUC-Eca-033339	Equus caballus	95.11	0.00e+00	1203.00
IUUC-Eeu-034909	Erinaceus europaeus	92.26	0.00e+00	989.00
IUUC-Fca-035780	Felis catus	94.93	0.00e+00	1218.00
IUUC-Fal-037447	Ficedula albicollis	79.38	0.00e+00	1018.00
IUUC-Gmo-038657	Gadus morhua	56.35	0.00e+00	1061.00
IUUC-Gga-040689	Gallus gallus	87.01	0.00e+00	1140.00
IUUC-Gac-041586	Gasterosteus aculeatus	63.44	0.00e+00	1332.00
IUUC-Hsa-046264	Homo sapiens	85.04	0.00e+00	1658.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	97.11	0.00e+00	1106.00
IUUC-Lch-050459	Latimeria chalumnae	80.70	0.00e+00	1101.00
IUUC-Loc-052774	Lepisosteus oculatus	68.84	0.00e+00	1403.00
IUUC-Laf-053765	Loxodonta africana	93.81	0.00e+00	1196.00
IUUC-Mcc-055052	Macaca mulatta	95.13	0.00e+00	1226.00
IUUC-Meu-056368	Macropus eugenii	93.45	0.00e+00	868.00
IUUC-Mga-059488	Meleagris gallopavo	86.53	0.00e+00	1147.00
IUUC-Mmr-061527	Microcebus murinus	95.26	0.00e+00	1229.00
IUUC-Mmu-063117	Mus musculus	93.66	0.00e+00	1212.00
IUUC-Mpu-066550	Mustela putorius furo	95.09	0.00e+00	1263.00
IUUC-Mlu-067772	Myotis lucifugus	90.70	0.00e+00	1118.00
IUUC-Nle-069215	Nomascus leucogenys	93.83	0.00e+00	1211.00
IUUC-Opr-070725	Ochotona princeps	72.22	0.00e+00	905.00
IUUC-Ont-072147	Oreochromis niloticus	69.00	0.00e+00	1022.00
IUUC-Ocu-073896	Oryctolagus cuniculus	84.21	0.00e+00	1641.00
IUUC-Ola-086767	Oryzias latipes	59.72	0.00e+00	1217.00
IUUC-Oga-088113	Otolemur garnettii	93.49	0.00e+00	1243.00
IUUC-Oar-089683	Ovis aries	90.94	0.00e+00	1167.00
IUUC-Ptr-091563	Pan troglodytes	95.13	0.00e+00	1227.00
IUUC-Pan-092042	Papio anubis	95.13	0.00e+00	1226.00
IUUC-Psi-093306	Pelodiscus sinensis	88.71	0.00e+00	1191.00
IUUC-Pma-094162	Petromyzon marinus	38.27	4.00e-46	178.00
IUUC-Ppa-095694	Physcomitrella patens	43.30	7.00e-169	587.00
IUUC-Pfo-096800	Poecilia formosa	71.36	0.00e+00	1007.00
IUUC-Pab-098356	Pongo abelii	95.13	0.00e+00	1228.00
IUUC-Pva-102246	Pteropus vampyrus	88.75	0.00e+00	1134.00
IUUC-Rno-105195	Rattus norvegicus	93.02	0.00e+00	1214.00
IUUC-Sha-107056	Sarcophilus harrisii	98.26	0.00e+00	1257.00
IUUC-Smo-109240	Selaginella moellendorffii	43.87	4.00e-146	511.00
IUUC-Sar-113301	Sorex araneus	85.03	5.00e-147	514.00
IUUC-Tgu-117127	Taeniopygia guttata	82.00	0.00e+00	1075.00
IUUC-Tru-118663	Takifugu rubripes	68.19	0.00e+00	966.00
IUUC-Tsy-119207	Tarsius syrichta	94.06	0.00e+00	863.00
IUUC-Tni-120705	Tetraodon nigroviridis	65.15	0.00e+00	956.00
IUUC-Tbe-127434	Tupaia belangeri	80.47	0.00e+00	1347.00
IUUC-Ttr-128937	Tursiops truncatus	94.61	0.00e+00	1224.00
IUUC-Vpa-130518	Vicugna pacos	88.43	0.00e+00	1105.00
IUUC-Xtr-131879	Xenopus tropicalis	77.83	0.00e+00	1050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence