iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033438

Ensembl Protein ID

ENSECAP00000016004.1

UniProt Accession

F7AX25; F7AX25_HORSE

Protein Name

Uncharacterized protein

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018037.1	ENSECAT00000019546.1	ENSECAP00000016004.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.90e-66	219.1	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF  +++
   Q: 270  AKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWKG--ELNGKEGVFPDNFALQIS 329
           689***************************************..9************98876 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LVDYIVEYDY DAIHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEVKRE 60
TESKDDNLPI KRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKRKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTTGACT ATATTGTGGA GTATGACTAT GATGCTATAC ATGATGATGA ATTAACTATT 60
CGAGTTGGGG AAATCATCAG GAACGTGAAA AAATTACAGG AGGAAGGATG GCTAGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	90.80	0.00e+00	998.00
IUUC-Apl-003573	Anas platyrhynchos	64.12	5.00e-161	561.00
IUUC-Aca-005118	Anolis carolinensis	65.09	2.00e-173	602.00
IUUC-Acl-008295	Aspergillus clavatus	31.29	8.00e-15	75.90
IUUC-Ame-010657	Astyanax mexicanus	45.20	4.00e-115	408.00
IUUC-Bta-012577	Bos taurus	85.38	0.00e+00	880.00
IUUC-Cja-020010	Callithrix jacchus	89.05	0.00e+00	966.00
IUUC-Cfa-020040	Canis familiaris	92.16	0.00e+00	980.00
IUUC-Cpo-021906	Cavia porcellus	81.17	0.00e+00	828.00
IUUC-Csa-024008	Chlorocebus sabaeus	89.83	0.00e+00	928.00
IUUC-Cho-024359	Choloepus hoffmanni	73.21	2.00e-62	233.00
IUUC-Csv-026228	Ciona savignyi	40.99	4.00e-25	106.00
IUUC-Dre-027661	Danio rerio	43.47	4.00e-111	395.00
IUUC-Dno-029568	Dasypus novemcinctus	86.12	0.00e+00	872.00
IUUC-Dor-030286	Dipodomys ordii	76.65	0.00e+00	728.00
IUUC-Dme-032184	Drosophila melanogaster	40.24	8.00e-27	115.00
IUUC-Ete-032576	Echinops telfairi	66.24	0.00e+00	626.00
IUUC-Eeu-034588	Erinaceus europaeus	72.60	3.00e-153	534.00
IUUC-Fca-036597	Felis catus	90.95	0.00e+00	1004.00
IUUC-Fal-037305	Ficedula albicollis	63.58	3.00e-166	578.00
IUUC-Gmo-039516	Gadus morhua	45.16	1.00e-67	250.00
IUUC-Gga-040979	Gallus gallus	66.31	7.00e-178	617.00
IUUC-Gac-041945	Gasterosteus aculeatus	40.43	1.00e-90	327.00
IUUC-Ggo-044488	Gorilla gorilla	90.30	0.00e+00	960.00
IUUC-Hsa-045909	Homo sapiens	90.30	0.00e+00	962.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	90.46	2.00e-127	448.00
IUUC-Lch-049481	Latimeria chalumnae	54.43	2.00e-159	556.00
IUUC-Loc-052715	Lepisosteus oculatus	52.43	5.00e-149	521.00
IUUC-Laf-053444	Loxodonta africana	86.90	0.00e+00	936.00
IUUC-Mcc-054844	Macaca mulatta	89.98	0.00e+00	929.00
IUUC-Meu-056491	Macropus eugenii	66.94	0.00e+00	644.00
IUUC-Mga-060154	Meleagris gallopavo	66.67	3.00e-178	618.00
IUUC-Mmr-061099	Microcebus murinus	89.36	0.00e+00	924.00
IUUC-Mdo-062769	Monodelphis domestica	71.19	0.00e+00	783.00
IUUC-Mmu-063136	Mus musculus	84.82	0.00e+00	809.00
IUUC-Mpu-066509	Mustela putorius furo	90.71	0.00e+00	913.00
IUUC-Mlu-067174	Myotis lucifugus	86.58	0.00e+00	906.00
IUUC-Nle-070147	Nomascus leucogenys	90.77	0.00e+00	970.00
IUUC-Opr-070752	Ochotona princeps	82.33	1.00e-171	596.00
IUUC-Ont-071810	Oreochromis niloticus	54.36	8.00e-101	361.00
IUUC-Oan-072731	Ornithorhynchus anatinus	72.16	2.00e-172	598.00
IUUC-Ocu-074331	Oryctolagus cuniculus	88.94	0.00e+00	913.00
IUUC-Ola-086404	Oryzias latipes	44.70	2.00e-93	336.00
IUUC-Oga-088200	Otolemur garnettii	89.98	0.00e+00	1027.00
IUUC-Oar-090423	Ovis aries	84.60	0.00e+00	848.00
IUUC-Ptr-091230	Pan troglodytes	90.45	0.00e+00	964.00
IUUC-Pan-091823	Papio anubis	90.14	0.00e+00	926.00
IUUC-Psi-093127	Pelodiscus sinensis	63.68	5.00e-165	574.00
IUUC-Pfo-096539	Poecilia formosa	50.00	9.00e-90	324.00
IUUC-Pab-097666	Pongo abelii	90.45	0.00e+00	952.00
IUUC-Pca-100812	Procavia capensis	81.32	6.00e-132	464.00
IUUC-Pva-102260	Pteropus vampyrus	83.73	0.00e+00	811.00
IUUC-Rno-106038	Rattus norvegicus	84.35	0.00e+00	843.00
IUUC-Sha-106975	Sarcophilus harrisii	72.27	0.00e+00	730.00
IUUC-Sar-113386	Sorex araneus	87.80	3.00e-111	395.00
IUUC-Ssc-115569	Sus scrofa	93.03	6.00e-118	416.00
IUUC-Tgu-117104	Taeniopygia guttata	65.49	0.00e+00	638.00
IUUC-Tru-117649	Takifugu rubripes	50.00	2.00e-96	347.00
IUUC-Tsy-119258	Tarsius syrichta	81.66	0.00e+00	864.00
IUUC-Tni-120755	Tetraodon nigroviridis	46.20	3.00e-126	445.00
IUUC-Tbe-127842	Tupaia belangeri	71.27	0.00e+00	673.00
IUUC-Ttr-129205	Tursiops truncatus	90.24	0.00e+00	839.00
IUUC-Vpa-130434	Vicugna pacos	86.13	0.00e+00	787.00
IUUC-Xtr-132766	Xenopus tropicalis	58.55	9.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence