iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065872

Ensembl Protein ID

ENSMPUP00000001537.1

UniProt Accession

M3XR37; M3XR37_MUSPF

Genbank Protein ID

ENSMPUP00000001537

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01055017

Gene Name

UBE2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000001552.1	ENSMPUT00000001569.1	ENSMPUP00000001537.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.80e-47	160.6	2	109

Active Site

Position(s)	Description	Evidence
55	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 29   ewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesp 117
            w+++i+Gpe+tp+e+g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  ++Wsp+++v+s+l+siqsll+epnp+sp
   Q: 2    VWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ--NRWSPTYDVSSILTSIQSLLDEPNPNSP 88
           6*********************************************************9..**************************** PP
   S: 118  lneeaaellkknreeykkkvr 138
           +n++aa+l+++n++ey+k+v+
   Q: 89   ANSQAAQLYQENKREYEKRVS 109
           ******************996 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVWNAVIFGP EGTPFEDGTF KLTIEFTEEY PNKPPTVRFV SKMFHPNVYA DGSICLDILQ 60
NRWSPTYDVS SILTSIQSLL DEPNPNSPAN SQAAQLYQEN KREYEKRVSA IVEQSWRDC 119

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NCGGCCCGGA GCGGACGCGG GTGCCGGACC GCGGGGCCCC TGTCTGTTCC CCTGAAGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0001701--P:in utero embryonic development
GO:0060135--P:maternal process involved in female pregnancy
GO:0008284--P:positive regulation of cell proliferation
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-025061	Choloepus hoffmanni	98.18	1.00e-59	220.00
IUUC-Fal-037474	Ficedula albicollis	100.00	2.00e-68	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence