iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120404

Ensembl Protein ID

ENSTNIP00000019044.1

UniProt Accession

H3DEV0; H3DEV0_TETNG

Protein Name

Uncharacterized protein

Gene Name

TLE4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000015956.1	ENSTNIT00000019272.1	ENSTNIP00000019044.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-23	80.2	616	654
UBD/Beta-Prp	4.70e-41	141.1	485	653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 616  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 654
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetl 133
           +h + v av++s+ +   v ++  + +kvwd+s   + ++v+ l   + +++++s+++ p+g +l++G++ +t+ +wdl t   +++ l
   Q: 485  SHGEVVCAVTISNPTR-HVYTGGKGCVKVWDIShpgNKTPVSQLDclNRDNYIRSCRLLPDGRTLIVGGERSTLSIWDLATTPRIKAEL 572
           4555788899999985.555555579*******999888888888889**************************************999 PP
   S: 134  sghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           +    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 573  TSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 653
           999999*************************************9.********************************99754 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MIRDLSKMYP PARHPVPHQP GQSLKFTVNE SCDRIKEEFH FLQAQYHSLK LECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVVP FLSQEHQQQV VQAVERAKQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTCGTG ATCTGAGCAA GATGTACCCC CCGGCGCGGC ATCCGGTAAG TAGAGAGCCG 60
AAGCAGCGCG TCCAATGGCA CGGGAACCAG CGCGCGTCTG ACGCGTAATC GCTTTGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005279	Anolis carolinensis	84.47	0.00e+00	1171.00
IUUC-Bta-012646	Bos taurus	83.31	0.00e+00	1193.00
IUUC-Cel-018361	Caenorhabditis elegans	55.32	5.00e-122	431.00
IUUC-Cja-019079	Callithrix jacchus	83.83	0.00e+00	1217.00
IUUC-Cfa-020987	Canis familiaris	84.13	0.00e+00	1178.00
IUUC-Cpo-021606	Cavia porcellus	82.75	0.00e+00	1159.00
IUUC-Csa-023445	Chlorocebus sabaeus	84.08	0.00e+00	1196.00
IUUC-Cho-024590	Choloepus hoffmanni	73.05	0.00e+00	1046.00
IUUC-Dno-028979	Dasypus novemcinctus	83.62	0.00e+00	1149.00
IUUC-Dor-030533	Dipodomys ordii	79.78	0.00e+00	1008.00
IUUC-Ete-032887	Echinops telfairi	74.65	0.00e+00	1045.00
IUUC-Eeu-035237	Erinaceus europaeus	71.92	0.00e+00	986.00
IUUC-Fca-036030	Felis catus	84.14	0.00e+00	1197.00
IUUC-Fal-037460	Ficedula albicollis	84.40	0.00e+00	1176.00
IUUC-Gga-040416	Gallus gallus	84.47	0.00e+00	1202.00
IUUC-Gac-041739	Gasterosteus aculeatus	78.18	0.00e+00	1112.00
IUUC-Ggo-045633	Gorilla gorilla	80.75	0.00e+00	1164.00
IUUC-Hsa-046461	Homo sapiens	80.76	0.00e+00	1192.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	84.21	0.00e+00	1202.00
IUUC-Lch-049943	Latimeria chalumnae	83.90	0.00e+00	1110.00
IUUC-Loc-052835	Lepisosteus oculatus	85.02	0.00e+00	1159.00
IUUC-Laf-053425	Loxodonta africana	84.27	0.00e+00	1193.00
IUUC-Mcc-055766	Macaca mulatta	80.76	0.00e+00	1192.00
IUUC-Meu-056209	Macropus eugenii	80.10	0.00e+00	1186.00
IUUC-Mmr-061317	Microcebus murinus	81.16	0.00e+00	1192.00
IUUC-Mdo-062956	Monodelphis domestica	84.21	0.00e+00	1202.00
IUUC-Mmu-063576	Mus musculus	84.21	0.00e+00	1189.00
IUUC-Mlu-067456	Myotis lucifugus	82.48	0.00e+00	1136.00
IUUC-Nle-069495	Nomascus leucogenys	84.14	0.00e+00	1167.00
IUUC-Ont-071419	Oreochromis niloticus	87.63	0.00e+00	1205.00
IUUC-Oan-072842	Ornithorhynchus anatinus	82.00	0.00e+00	1178.00
IUUC-Ocu-074453	Oryctolagus cuniculus	83.06	0.00e+00	1178.00
IUUC-Ola-087090	Oryzias latipes	86.71	0.00e+00	1198.00
IUUC-Oga-087939	Otolemur garnettii	84.21	0.00e+00	1202.00
IUUC-Ptr-091048	Pan troglodytes	84.08	0.00e+00	1196.00
IUUC-Pan-091973	Papio anubis	79.59	0.00e+00	1141.00
IUUC-Pfo-097518	Poecilia formosa	87.28	0.00e+00	1146.00
IUUC-Pva-103037	Pteropus vampyrus	79.01	0.00e+00	1189.00
IUUC-Rno-105314	Rattus norvegicus	83.74	0.00e+00	1125.00
IUUC-Sar-113585	Sorex araneus	76.26	0.00e+00	634.00
IUUC-Ssc-116408	Sus scrofa	84.02	0.00e+00	1217.00
IUUC-Tgu-117068	Taeniopygia guttata	84.26	0.00e+00	1183.00
IUUC-Tru-118782	Takifugu rubripes	88.99	0.00e+00	1216.00
IUUC-Tsy-118884	Tarsius syrichta	71.62	0.00e+00	936.00
IUUC-Ttr-129285	Tursiops truncatus	79.62	0.00e+00	1179.00
IUUC-Vpa-130577	Vicugna pacos	68.45	5.00e-155	541.00
IUUC-Xtr-132974	Xenopus tropicalis	82.74	0.00e+00	1147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence