iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-094034

Ensembl Protein ID

ENSPSIP00000015442.1

UniProt Accession

K7G581; K7G581_PELSI

Genbank Protein ID

ENSPSIP00000015442

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AGCU01204843

Gene Name

PRKAA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000013615.1	ENSPSIT00000015514.1	ENSPSIP00000015442.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	51.59	4.00e-114	409.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	40.35	5.00e-97	349.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MRRLGSWLKM AAADKQKHEH GRVKIGHYIL GDTLGVGTFG KVKVGKHELT GHKVAVKILN 60
RQKIRSLDVV GKIRREIQNL KLFRHPHIIK LYQVISTPSD IFMVMEYVSG GELFDYICKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGCAGAC TCGGCTCCTG GCTCAAGATG GCGGCGGCGG ATAAACAGAA ACATGAACAC 60
GGGCGGGTGA AGATCGGGCA CTACATCCTG GGGGACACGC TGGGCGTCGG CACCTTCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005623--C:cell
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0061762--P:CAMKK-AMPK signaling cascade
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0019395--P:fatty acid oxidation
GO:0042593--P:glucose homeostasis
GO:0006006--P:glucose metabolic process
GO:0031649--P:heat generation
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0050995--P:negative regulation of lipid catabolic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0010628--P:positive regulation of gene expression
GO:0048643--P:positive regulation of skeletal muscle tissue development
GO:0042752--P:regulation of circadian rhythm
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1904101--P:response to acadesine
GO:1901563--P:response to camptothecin
GO:0010332--P:response to gamma radiation
GO:0042542--P:response to hydrogen peroxide
GO:0009411--P:response to UV

KEGG

pss:102444277

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	46.76	2.00e-119	422.00
IUUC-Aml-001907	Ailuropoda melanoleuca	93.58	0.00e+00	1006.00
IUUC-Atr-002770	Amborella trichopoda	48.27	1.00e-124	439.00
IUUC-Apl-003395	Anas platyrhynchos	73.61	0.00e+00	792.00
IUUC-Aca-004480	Anolis carolinensis	78.94	0.00e+00	808.00
IUUC-Aly-006289	Arabidopsis lyrata	51.14	4.00e-122	431.00
IUUC-Ath-007014	Arabidopsis thaliana	51.59	2.00e-123	435.00
IUUC-Ago-007957	Ashbya gossypii	41.31	1.00e-112	399.00
IUUC-Acl-008103	Aspergillus clavatus	58.99	8.00e-99	354.00
IUUC-Afl-008555	Aspergillus flavus	58.27	4.00e-99	355.00
IUUC-Afu-008949	Aspergillus fumigatus	44.85	2.00e-99	357.00
IUUC-Ani-009408	Aspergillus nidulans	59.27	4.00e-99	355.00
IUUC-Ang-009551	Aspergillus niger	58.99	5.00e-100	358.00
IUUC-Aor-010176	Aspergillus oryzae	58.27	5.00e-99	355.00
IUUC-Ate-010287	Aspergillus terreus	60.45	1.00e-98	353.00
IUUC-Ame-011019	Astyanax mexicanus	73.57	0.00e+00	824.00
IUUC-Bgr-012045	Blumeria graminis	57.91	9.00e-99	354.00
IUUC-Bta-012786	Bos taurus	93.23	0.00e+00	1004.00
IUUC-Bci-013774	Botrytis cinerea	45.75	6.00e-101	361.00
IUUC-Bdi-014319	Brachypodium distachyon	47.17	2.00e-120	425.00
IUUC-Bol-016242	Brassica oleracea	51.77	3.00e-124	438.00
IUUC-Bra-016750	Brassica rapa	52.47	2.00e-124	439.00
IUUC-Cel-018518	Caenorhabditis elegans	57.29	3.00e-176	611.00
IUUC-Cja-019386	Callithrix jacchus	74.19	0.00e+00	844.00
IUUC-Cfa-020177	Canis familiaris	94.03	0.00e+00	962.00
IUUC-Cpo-021805	Cavia porcellus	74.19	0.00e+00	843.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	55.76	1.00e-95	342.00
IUUC-Csa-024267	Chlorocebus sabaeus	74.37	0.00e+00	844.00
IUUC-Cho-024859	Choloepus hoffmanni	91.54	0.00e+00	950.00
IUUC-Cin-025550	Ciona intestinalis	58.79	0.00e+00	654.00
IUUC-Csv-026139	Ciona savignyi	57.95	0.00e+00	650.00
IUUC-Cne-027044	Cryptococcus neoformans	46.51	9.00e-104	370.00
IUUC-Cme-027289	Cyanidioschyzon merolae	46.35	4.00e-112	398.00
IUUC-Dre-027749	Danio rerio	84.99	0.00e+00	943.00
IUUC-Dno-030006	Dasypus novemcinctus	93.40	0.00e+00	1003.00
IUUC-Dor-030578	Dipodomys ordii	74.19	0.00e+00	842.00
IUUC-Dse-031507	Dothistroma septosporum	60.14	9.00e-104	371.00
IUUC-Dme-031704	Drosophila melanogaster	56.38	1.00e-175	609.00
IUUC-Ete-033055	Echinops telfairi	90.65	0.00e+00	1008.00
IUUC-Eca-034239	Equus caballus	94.21	0.00e+00	962.00
IUUC-Fca-035754	Felis catus	90.40	0.00e+00	988.00
IUUC-Fal-037363	Ficedula albicollis	96.61	0.00e+00	1025.00
IUUC-Fox-038073	Fusarium oxysporum	58.25	6.00e-101	361.00
IUUC-Fso-038236	Fusarium solani	57.54	2.00e-97	350.00
IUUC-Gmo-039633	Gadus morhua	81.24	0.00e+00	963.00
IUUC-Ggr-039987	Gaeumannomyces graminis	50.00	4.00e-101	362.00
IUUC-Gga-040546	Gallus gallus	74.32	0.00e+00	843.00
IUUC-Gac-041822	Gasterosteus aculeatus	71.81	0.00e+00	793.00
IUUC-Gma-042712	Glycine max	48.06	3.00e-124	438.00
IUUC-Ggo-044797	Gorilla gorilla	93.76	0.00e+00	1007.00
IUUC-Hsa-045867	Homo sapiens	93.58	0.00e+00	1006.00
IUUC-Hvu-047406	Hordeum vulgare	46.69	1.00e-121	429.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	74.37	0.00e+00	846.00
IUUC-Kpa-049190	Komagataella pastoris	43.59	1.00e-115	409.00
IUUC-Lch-049623	Latimeria chalumnae	89.31	0.00e+00	949.00
IUUC-Lpe-051392	Leersia perrieri	52.47	3.00e-125	441.00
IUUC-Loc-052362	Lepisosteus oculatus	90.37	0.00e+00	925.00
IUUC-Lma-053054	Leptosphaeria maculans	58.42	1.00e-105	377.00
IUUC-Laf-053799	Loxodonta africana	93.40	0.00e+00	1038.00
IUUC-Mcc-055862	Macaca mulatta	74.37	0.00e+00	847.00
IUUC-Mor-057170	Magnaporthe oryzae	49.73	1.00e-101	363.00
IUUC-Mpo-057302	Magnaporthe poae	50.00	2.00e-101	363.00
IUUC-Mtr-058309	Medicago truncatula	48.02	6.00e-123	434.00
IUUC-Mla-059058	Melampsora laricipopulina	41.42	5.00e-105	374.00
IUUC-Mga-059206	Meleagris gallopavo	74.14	0.00e+00	791.00
IUUC-Mvi-060337	Microbotryum violaceum	50.28	1.00e-99	357.00
IUUC-Mmr-061761	Microcebus murinus	93.40	0.00e+00	1004.00
IUUC-Mdo-062160	Monodelphis domestica	73.87	0.00e+00	837.00
IUUC-Mmu-063406	Mus musculus	74.01	0.00e+00	839.00
IUUC-Mac-064518	Musa acuminata	49.25	1.00e-117	416.00
IUUC-Mpu-066326	Mustela putorius furo	73.80	0.00e+00	792.00
IUUC-Mlu-068227	Myotis lucifugus	94.40	0.00e+00	963.00
IUUC-Nfi-068493	Neosartorya fischeri	45.16	6.00e-99	355.00
IUUC-Ncr-068665	Neurospora crassa	58.16	2.00e-103	370.00
IUUC-Nle-070158	Nomascus leucogenys	74.37	0.00e+00	848.00
IUUC-Opr-070272	Ochotona princeps	89.39	0.00e+00	989.00
IUUC-Ont-072027	Oreochromis niloticus	82.66	0.00e+00	922.00
IUUC-Oan-073322	Ornithorhynchus anatinus	86.83	0.00e+00	952.00
IUUC-Ocu-074188	Oryctolagus cuniculus	90.99	0.00e+00	974.00
IUUC-Oba-075436	Oryza barthii	48.03	7.00e-126	443.00
IUUC-Obr-076507	Oryza brachyantha	48.36	9.00e-127	446.00
IUUC-Ogl-077718	Oryza glaberrima	52.20	2.00e-121	429.00
IUUC-Ogu-078349	Oryza glumaepatula	48.03	1.00e-125	443.00
IUUC-Oin-079889	Oryza indica	47.43	7.00e-122	430.00
IUUC-Olo-080521	Oryza longistaminata	48.03	7.00e-126	443.00
IUUC-Ome-081630	Oryza meridionalis	47.83	2.00e-125	442.00
IUUC-Oni-082211	Oryza nivara	48.03	5.00e-126	444.00
IUUC-Opu-083617	Oryza punctata	47.93	4.00e-125	441.00
IUUC-Oru-084252	Oryza rufipogon	48.03	6.00e-126	444.00
IUUC-Osa-085548	Oryza sativa	48.03	6.00e-126	444.00
IUUC-Ola-086366	Oryzias latipes	83.30	0.00e+00	945.00
IUUC-Olu-087861	Ostreococcus lucimarinus	48.52	3.00e-116	411.00
IUUC-Oga-088003	Otolemur garnettii	93.58	0.00e+00	1006.00
IUUC-Oar-089933	Ovis aries	93.23	0.00e+00	1004.00
IUUC-Ptr-090718	Pan troglodytes	93.58	0.00e+00	1006.00
IUUC-Pan-092526	Papio anubis	93.76	0.00e+00	1006.00
IUUC-Pno-095030	Phaeosphaeria nodorum	58.48	2.00e-104	372.00
IUUC-Ppa-095615	Physcomitrella patens	51.15	7.00e-122	430.00
IUUC-Pfo-097050	Poecilia formosa	82.19	0.00e+00	927.00
IUUC-Pab-098519	Pongo abelii	93.58	0.00e+00	1006.00
IUUC-Pop-100042	Populus trichocarpa	51.98	6.00e-126	444.00
IUUC-Pca-101104	Procavia capensis	93.05	0.00e+00	744.00
IUUC-Ppe-101642	Prunus persica	49.26	3.00e-123	434.00
IUUC-Pva-102470	Pteropus vampyrus	74.19	0.00e+00	837.00
IUUC-Pgr-103406	Puccinia graminis	56.45	4.00e-90	325.00
IUUC-Ptt-103713	Puccinia triticina	48.47	8.00e-72	264.00
IUUC-Pte-104259	Pyrenophora teres	60.51	6.00e-104	371.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	60.87	2.00e-104	373.00
IUUC-Rno-104960	Rattus norvegicus	74.01	0.00e+00	843.00
IUUC-Sce-106290	Saccharomyces cerevisiae	40.86	8.00e-112	397.00
IUUC-Sha-107603	Sarcophilus harrisii	94.12	0.00e+00	1009.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	51.54	5.00e-109	388.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.35	5.00e-106	378.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	43.82	2.00e-100	359.00
IUUC-Smo-109309	Selaginella moellendorffii	46.25	4.00e-123	434.00
IUUC-Sit-109745	Setaria italica	52.93	2.00e-126	445.00
IUUC-Sly-110890	Solanum lycopersicum	52.09	1.00e-123	436.00
IUUC-Stu-112144	Solanum tuberosum	46.17	8.00e-117	413.00
IUUC-Sar-113521	Sorex araneus	84.53	0.00e+00	831.00
IUUC-Sbi-114764	Sorghum bicolor	48.16	2.00e-127	448.00
IUUC-Sre-115141	Sporisorium reilianum	66.18	2.00e-112	399.00
IUUC-Ssc-115732	Sus scrofa	94.02	0.00e+00	961.00
IUUC-Tgu-117190	Taeniopygia guttata	96.26	0.00e+00	1020.00
IUUC-Tru-118735	Takifugu rubripes	72.81	0.00e+00	811.00
IUUC-Tsy-119503	Tarsius syrichta	70.88	0.00e+00	746.00
IUUC-Tni-119833	Tetraodon nigroviridis	83.39	0.00e+00	934.00
IUUC-Tca-121386	Theobroma cacao	47.95	2.00e-124	438.00
IUUC-Tre-122070	Trichoderma reesei	57.67	2.00e-103	369.00
IUUC-Tvi-122305	Trichoderma virens	56.95	2.00e-101	362.00
IUUC-Tae-123515	Triticum aestivum	48.04	9.00e-126	443.00
IUUC-Tur-126416	Triticum urartu	46.60	6.00e-121	427.00
IUUC-Tme-127174	Tuber melanosporum	41.47	2.00e-68	253.00
IUUC-Tbe-127791	Tupaia belangeri	76.96	9.00e-102	363.00
IUUC-Ttr-129224	Tursiops truncatus	90.80	0.00e+00	993.00
IUUC-Uma-129372	Ustilago maydis	65.09	2.00e-111	396.00
IUUC-Vda-129819	Verticillium dahliae	52.98	7.00e-85	308.00
IUUC-Vpa-130220	Vicugna pacos	73.37	0.00e+00	784.00
IUUC-Vvi-131649	Vitis vinifera	47.96	2.00e-124	438.00
IUUC-Xtr-132954	Xenopus tropicalis	74.59	0.00e+00	842.00
IUUC-Xma-134082	Xiphophorus maculatus	89.29	0.00e+00	856.00
IUUC-Yli-134422	Yarrowia lipolytica	43.15	8.00e-116	410.00
IUUC-Zma-135621	Zea mays	54.99	2.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence