iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117964

UUCD1 version

UUC-TaR-00308

Ensembl Protein ID

ENSTRUP00000013348.1

UniProt Accession

H2SLR2; H2SLR2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

traf3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005547.1	ENSTRUT00000013410.1	ENSTRUP00000013348.1
ENSTRUG00000005547.1	ENSTRUT00000013411.1	ENSTRUP00000013349.1
ENSTRUG00000005547.1	ENSTRUT00000013412.1	ENSTRUP00000013350.1
ENSTRUG00000005547.1	ENSTRUT00000013413.1	ENSTRUP00000013351.1
ENSTRUG00000005547.1	ENSTRUT00000013414.1	ENSTRUP00000013352.1
ENSTRUG00000005547.1	ENSTRUT00000013415.1	ENSTRUP00000013353.1
ENSTRUG00000005547.1	ENSTRUT00000013416.1	ENSTRUP00000013354.1
ENSTRUG00000005547.1	ENSTRUT00000013417.1	ENSTRUP00000013355.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	57.54	3.00e-179	625.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSAGRSTDGR EVQIPLQQAA PSLAMPLSVA PLLTSHCVPA GFLPLHGGFR DHFVEALEAK 60
YCCESCRLVL CQPRQTECGH RFCQSCINDI LSHPNPVCPA DTEPLFKDKV FRDVCCHREI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGCAG GGAGGAGCAC TGATGGGAGG GAGGTGCAGA TTCCCCTCCA GCAGGCAGCA 60
CCTTCTTTGG CCATGCCCCT CTCAGTGGCA CCGCTCCTCA CGTCACACTC GCACCGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0001817--P:regulation of cytokine production
GO:0050688--P:regulation of defense response to virus
GO:0001878--P:response to yeast
GO:0008063--P:Toll signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	57.17	0.00e+00	645.00
IUUC-Apl-004189	Anas platyrhynchos	58.29	0.00e+00	665.00
IUUC-Aca-004540	Anolis carolinensis	57.12	0.00e+00	655.00
IUUC-Ath-007062	Arabidopsis thaliana	29.17	9.00e-09	55.10
IUUC-Ang-009779	Aspergillus niger	22.54	6.00e-13	68.60
IUUC-Ame-010645	Astyanax mexicanus	73.10	0.00e+00	833.00
IUUC-Bgr-012191	Blumeria graminis	25.46	3.00e-16	79.70
IUUC-Bta-013140	Bos taurus	57.41	0.00e+00	651.00
IUUC-Cja-019436	Callithrix jacchus	57.73	0.00e+00	648.00
IUUC-Cfa-021072	Canis familiaris	57.17	0.00e+00	646.00
IUUC-Cpo-022472	Cavia porcellus	58.10	0.00e+00	655.00
IUUC-Csa-024217	Chlorocebus sabaeus	56.55	0.00e+00	648.00
IUUC-Cho-025066	Choloepus hoffmanni	50.11	1.00e-136	479.00
IUUC-Csv-026078	Ciona savignyi	67.24	6.00e-77	279.00
IUUC-Dre-028208	Danio rerio	74.14	0.00e+00	843.00
IUUC-Dno-028868	Dasypus novemcinctus	57.73	0.00e+00	650.00
IUUC-Dor-031056	Dipodomys ordii	57.97	3.00e-167	581.00
IUUC-Ete-033005	Echinops telfairi	50.33	6.00e-135	474.00
IUUC-Eca-033717	Equus caballus	57.33	0.00e+00	645.00
IUUC-Eeu-035172	Erinaceus europaeus	37.94	6.00e-64	238.00
IUUC-Fca-035688	Felis catus	57.25	0.00e+00	642.00
IUUC-Fal-037176	Ficedula albicollis	58.10	0.00e+00	663.00
IUUC-Gmo-038931	Gadus morhua	73.13	0.00e+00	752.00
IUUC-Gga-040519	Gallus gallus	41.37	6.00e-119	421.00
IUUC-Gac-042019	Gasterosteus aculeatus	84.08	0.00e+00	931.00
IUUC-Ggo-044424	Gorilla gorilla	57.73	0.00e+00	647.00
IUUC-Hsa-046957	Homo sapiens	57.54	0.00e+00	645.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	58.10	0.00e+00	654.00
IUUC-Lch-050680	Latimeria chalumnae	55.30	0.00e+00	630.00
IUUC-Lpe-050771	Leersia perrieri	25.98	2.00e-08	55.10
IUUC-Loc-052093	Lepisosteus oculatus	71.63	0.00e+00	850.00
IUUC-Laf-054573	Loxodonta africana	55.96	0.00e+00	626.00
IUUC-Mcc-055049	Macaca mulatta	56.37	0.00e+00	644.00
IUUC-Mga-059244	Meleagris gallopavo	58.10	0.00e+00	665.00
IUUC-Mmr-061469	Microcebus murinus	56.71	0.00e+00	653.00
IUUC-Mdo-063049	Monodelphis domestica	54.85	0.00e+00	650.00
IUUC-Mmu-063763	Mus musculus	57.73	0.00e+00	649.00
IUUC-Mpu-065956	Mustela putorius furo	57.36	0.00e+00	645.00
IUUC-Mlu-067482	Myotis lucifugus	56.80	0.00e+00	634.00
IUUC-Nle-069941	Nomascus leucogenys	57.73	0.00e+00	649.00
IUUC-Opr-071027	Ochotona princeps	75.89	3.00e-105	375.00
IUUC-Ont-071914	Oreochromis niloticus	83.65	0.00e+00	979.00
IUUC-Oan-072802	Ornithorhynchus anatinus	56.98	0.00e+00	647.00
IUUC-Ocu-074075	Oryctolagus cuniculus	57.51	0.00e+00	645.00
IUUC-Oba-075596	Oryza barthii	25.76	5.00e-08	53.90
IUUC-Ogl-077360	Oryza glaberrima	25.76	3.00e-08	53.50
IUUC-Ogu-078462	Oryza glumaepatula	25.76	5.00e-08	53.90
IUUC-Oin-079887	Oryza indica	25.76	1.00e-07	52.80
IUUC-Ome-082014	Oryza meridionalis	25.76	3.00e-08	54.70
IUUC-Oni-083105	Oryza nivara	25.76	6.00e-08	53.50
IUUC-Oru-084831	Oryza rufipogon	25.76	5.00e-08	53.90
IUUC-Ola-086783	Oryzias latipes	36.03	3.00e-96	345.00
IUUC-Oga-088149	Otolemur garnettii	56.78	0.00e+00	650.00
IUUC-Oar-089922	Ovis aries	54.95	2.00e-174	605.00
IUUC-Ptr-091412	Pan troglodytes	57.54	0.00e+00	645.00
IUUC-Pan-092789	Papio anubis	56.55	0.00e+00	648.00
IUUC-Psi-093603	Pelodiscus sinensis	58.12	0.00e+00	666.00
IUUC-Pma-094463	Petromyzon marinus	49.48	2.00e-140	491.00
IUUC-Pfo-096518	Poecilia formosa	82.20	0.00e+00	979.00
IUUC-Pab-097664	Pongo abelii	57.73	0.00e+00	647.00
IUUC-Pca-100821	Procavia capensis	54.75	1.00e-157	549.00
IUUC-Pva-103201	Pteropus vampyrus	54.26	2.00e-169	588.00
IUUC-Rno-105505	Rattus norvegicus	57.17	0.00e+00	644.00
IUUC-Sha-107416	Sarcophilus harrisii	57.17	0.00e+00	650.00
IUUC-Ssc-115351	Sus scrofa	57.41	0.00e+00	648.00
IUUC-Tgu-116608	Taeniopygia guttata	58.10	0.00e+00	664.00
IUUC-Tsy-119571	Tarsius syrichta	38.71	2.00e-106	379.00
IUUC-Tni-120211	Tetraodon nigroviridis	93.32	0.00e+00	1016.00
IUUC-Tbe-127412	Tupaia belangeri	41.89	6.00e-110	390.00
IUUC-Vpa-130074	Vicugna pacos	57.63	3.00e-148	518.00
IUUC-Xtr-132563	Xenopus tropicalis	54.50	0.00e+00	650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence